Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sandra Dreisigacker"'
Autor:
Bettina Hinkelmann, Christopher Knopf, Sandra Dreisigacker, Dirk Menche, Paul R. Wosniok, J. Manuel Orozco-Rodriguez, Peter P. Mueller, Mark Brönstrup
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany)
Germany
Chemistry (Weinheim an Der Bergstrasse, Germany)
Germany
Chemistry (Weinheim an Der Bergstrasse, Germany)
Leupyrrins are highly potent antifungal agents. A structure–activity‐relationship study of natural and synthetic derivatives is reported which reveals important insights into the biological relevance of several structural subunits leading to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35086b93710d5f1f1e32777de047338a
https://pubmed.ncbi.nlm.nih.gov/33174290
https://pubmed.ncbi.nlm.nih.gov/33174290
Autor:
Christopher Knopf, J. Manuel Orozco-Rodriguez, Paul R. Wosniok, Peter P. Mueller, Sandra Dreisigacker, Mark Brönstrup, Dirk Menche, Bettina Hinkelmann
Publikováno v:
Chemistry – A European Journal. 26:15047-15047
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332f634a773d32687f78f55374bbfc8e
https://doi.org/10.1002/chem.202003844
https://doi.org/10.1002/chem.202003844
Autor:
Daniel Herkommer, Holger Gohlke, Dirk Menche, Galina Sergeev, Sandra Dreisigacker, Florenz Sasse
Publikováno v:
ChemMedChem. 10:470-489
The natural products rhizopodin and bistramide belong to an elite class of highly potent actin binding agents. They show powerful antiproliferative activities against a range of tumor cell lines, with IC50 values in the low-nanomolar range. At the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576eacf76ec2e906f9d965f23953794b
https://doi.org/10.1002/cmdc.201402508
https://doi.org/10.1002/cmdc.201402508
Autor:
Edith Neu, Sandra Dreisigacker, Stefan Kehraus, Till F. Schäberle, Stephan Felder, Gabriele M. König, Gabriele Bierbaum, Patrick R. Wright, Dirk Menche
Publikováno v:
Chemistry - A European Journal. 19:9319-9324
Marine myxobacteria (Enhygromyxa, Plesiocystis, Pseudoenhygromyxa, Haliangium) are phylogenetically distant from their terrestrial counterparts. Salimabromide is the first natural product from the Plesiocystis/Enhygromyxa clade of obligatory marine m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9926cdf6bad25ba5219128e741b9571
https://doi.org/10.1002/chem.201301379
https://doi.org/10.1002/chem.201301379
Publikováno v:
The Journal of Organic Chemistry. 77:10782-10788
A highly convergent synthesis of the central dimeric core of the potent antibiotic macrolide rhizopodin is reported. Notable features of the highly concise route include an effective preparation of the key C8-C22 building block based on an iridium-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ba97c63e0d6517a5208a106de970a3
https://doi.org/10.1021/jo302134y
https://doi.org/10.1021/jo302134y
Autor:
Sandra Dreisigacker, Dirk Menche
Publikováno v:
Modeling of Molecular Properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc6ff7b6cd5f3153a6d66d8592752286
https://doi.org/10.1002/9783527636402.ch24
https://doi.org/10.1002/9783527636402.ch24
Autor:
Sebastian Thiede, Sandra Dreisigacker, Herbert Irschik, Maoqun Tian, Dirk Menche, Thomas Debnar, Daniel Herkommer, Paul R. Wosniok
Publikováno v:
ChemInform. 46
The relative and absolute configurations of potent antifungal agents leupyrrin A1 (I) and B1 (II) are determined by a combination of high field NMR studies, molecular modeling, and chemical derivatization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c158ff51f5448db56094a79434f353d
https://doi.org/10.1002/chin.201535239
https://doi.org/10.1002/chin.201535239
Autor:
Herbert Irschik, Maoqun Tian, Sebastian Thiede, Sandra Dreisigacker, Paul R. Wosniok, Daniel Herkommer, Dirk Menche, Thomas Debnar
Publikováno v:
Journal of the American Chemical Society. 137(12)
The stereochemical determination of the potent antifungal agents leupyrrin A1 and B1 and the total synthesis of leupyrrin A1 are reported. The relative and absolute configuration was determined by a combination of high field NMR studies, molecular mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af5974bdd264802ddd7eb54b7b837e9
https://pubmed.ncbi.nlm.nih.gov/25769018
https://pubmed.ncbi.nlm.nih.gov/25769018
Publikováno v:
ChemInform. 44
An efficient method for the highly regioselective opening of aliphatic zirconacyclopentadienes based on a novel concept of remote stereorelay is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2dedb79bccf7b78eb8375f231fe0c3c
https://doi.org/10.1002/chin.201320115
https://doi.org/10.1002/chin.201320115
Publikováno v:
Chemical communications (Cambridge, England). 49(7)
An efficient protocol for the highly regioselective opening of aliphatic zirconacyclopentadienes is reported. The one-pot process involves a zirconocene-mediated cyclization of 1,6-diynes and highly selective cleavage of the metallacycles with NBS an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7487b0c628f75f4336fdf2fcf4f5ebc
https://pubmed.ncbi.nlm.nih.gov/23230573
https://pubmed.ncbi.nlm.nih.gov/23230573