Výsledky vyhledávání - "Sandra Dietschy"

Abstract CT149: MP0250, a VEGF- and HGF-blocking multi-DARPin drug candidate, in combination with tyrosine-kinase-inhibitors targeting EGFR-mutated NSCLC: Preclinical rationale and phase Ib/II study outline

Autor: Keith M. Dawson, Frank Hermann, Andreas Harstrick, Michael T. Stumpp, Joachim Kiemle-Kallee, Jutta Haunschild, Ulrike Fiedler, Sandra Dietschy

Publikováno v: Cancer Research. 78:CT149-CT149

Background: Relapse of patients with EGFR-mutated NSCLC treated with TKI regimens is most often due to TK mutation but also in a significant number of cases due to upregulation of bypass pathways, the most common being the HGF/cMET signaling pathway.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f8cd323aa997dfc981304ea494f9146
https://doi.org/10.1158/1538-7445.am2018-ct149

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