Influence of pro-obesogenic dietary habits on stress-induced cognitive alterations in healthy adult volunteers

Autor: Inês Delgado, Sandra Dexpert, Julie Sauvant, John F. Cryan, Lucile Capuron

Publikováno v: Neurobiology of Stress, Vol 15, Iss , Pp 100353- (2021)

Stress is a fundamental biological response that can be associated with alterations in cognitive processes. Unhealthy dietary habits are proposed to modulate this effect, notably through their pro-inflammatory potential. This cross-sectional study ai

Externí odkaz: https://doaj.org/article/8f545b967ad340e5840b05d90e377d8f

Low omega-3 polyunsaturated fatty acids predict reduced response to standard antidepressants in patients with major depressive disorder

Autor: Sofia Cussotto, Inês Delgado, Giovanni Oriolo, Jonas Kemper, Diane Begarie, Sandra Dexpert, Julie Sauvant, Marion Leboyer, Bruno Aouizerate, Rocío Martin‐Santos, Martin Schaefer, Lucile Capuron

Publikováno v: Depression and anxietyREFERENCES. 39(5)

Major depressive disorder (MDD) is characterized by a high rate of treatment resistance. Omega (ω)-3 polyunsaturated fatty acids (PUFAs) were shown to correlate with depressive phenotype both in rodents and in humans. However, few studies to date ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d9188a28340e9fdb1a722389f6bb25
https://pubmed.ncbi.nlm.nih.gov/35357051

Transcriptomic signaling pathways involved in a naturalistic model of inflammation-related depression and its remission

Autor: Sandra Dexpert, Marie-Pierre Moisan, Cédric Beau, Patrick Ledaguenel, Eric Magne, Lucile Capuron, Steve W. Cole, Aline Foury, Damien Forestier

Publikováno v: Translational Psychiatry
Translational Psychiatry, Nature Pub. Group, 2021, 11, pp.203. ⟨10.1038/s41398-021-01323-9⟩
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)

This study aimed at identifying molecular biomarkers of inflammation-related depression in order to improve diagnosis and treatment. We performed whole-genome expression profiling from peripheral blood in a naturalistic model of inflammation-associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20d063c30481920b2cb8c54e819bdf3
https://hal.archives-ouvertes.fr/hal-03190850

Reward-related brain activity and behavior are associated with peripheral ghrelin levels in obesity

Autor: Volodymyr B. Bogdanov, Helen Beyer, Giuseppe Pagnoni, Bruno Aouizerate, Guillaume Ferreira, Lucile Capuron, Bixente Dilharreguy, Sandra Dexpert, Jennifer C. Felger, Ines Delgado, Cédric Beau, Patrick Ledaguenel, Damien Forestier, Olena V. Bogdanova, Eric Magne, Sophie Layé, Agnès Aubert

Publikováno v: Psychoneuroendocrinology
Psychoneuroendocrinology, Elsevier, 2020, 112, pp.1-8. ⟨10.1016/j.psyneuen.2019.104520⟩
Psychoneuroendocrinology, 2020, 112, pp.1-8. ⟨10.1016/j.psyneuen.2019.104520⟩

International audience; Background/objectives: While excessive food consumption represents a key factor in the development of obesity, the underlying mechanisms are still unclear. Ghrelin, a gut-brain hormone involved in the regulation of appetite, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a62e1d7a7e359a9169c3ec694a3b4a
http://hdl.handle.net/20.500.12278/112067

Depressive symptoms in obesity: Relative contribution of low-grade inflammation and metabolic health

Autor: Patrick Ledaguenel, Bruno Aouizerate, Cédric Beau, Lison Huet, Ines Delgado, Agnès Aubert, Lucile Capuron, Sandra Dexpert, Julie Sauvant, Damien Forestier, Eric Magne

Publikováno v: Psychoneuroendocrinology
Psychoneuroendocrinology, Elsevier, 2018, 91, pp.55-61. ⟨10.1016/j.psyneuen.2018.02.030⟩

International audience; Background Recent reports suggest that the risk of depressive symptoms in obesity is potentiated in subjects presenting a metabolically unhealthy phenotype. Inflammation is often considered a defining criteria of metabolic hea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8646bec821ff38e74b896e3560bc08
https://hal.inrae.fr/hal-02626878