Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sandra D. O'Dell"'
Autor:
Maryam Al-Hilal, Aseel AlSaleh, Zoitsa Maniou, Fiona J. Lewis, Wendy L. Hall, Thomas A.B. Sanders, Sandra D. O'Dell
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 2, Pp 542-551 (2013)
Delta-5 and delta-6 desaturases (D5D and D6D) are key enzymes in endogenous synthesis of long-chain PUFAs. In this sample of healthy subjects (n = 310), genotypes of single nucleotide polymorphisms (SNPs) rs174537, rs174561, and rs3834458 in the FADS
Externí odkaz:
https://doaj.org/article/504d23bd81464782a12b50bb96f837d2
Autor:
Aseel AlSaleh, Sandra D. O'Dell, Gary S. Frost, Bruce A. Griffin, Julie A. Lovegrove, Susan A. Jebb, Thomas A.B. Sanders
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2298-2303 (2011)
The PPARγ2 gene single nucleotide polymorphism (SNP) Pro12Ala has shown variable association with metabolic syndrome traits in healthy subjects. The RISCK Study investigated the effect of interaction between genotype and the ratio of polyunsaturated
Externí odkaz:
https://doaj.org/article/e034c1f3f1fe4931838a181b5ab04727
Publikováno v:
BioTechniques, Vol 32, Iss 5, Pp 1080-1089 (2002)
After PCR amplification, we have achieved precise sizing of trinucleotide and tetranucleotide microsatellite alleles on 96-well open-faced polyacrylamide microplate array diagonal gel electrophoresis (MADGE) gels: two tetranucleotide repeats, HUMTH01
Externí odkaz:
https://doaj.org/article/f13c99b044f8490eae08229212b3482e
Publikováno v:
BioTechniques, Vol 29, Iss 3, Pp 500-506 (2000)
A new modification of the microplate array diagonal gel electrophoresis (MADGE) system accommodates the dual amplification refractory mutation system (ARMSTM) products of 96 samples on one 192-well gel. Simultaneous electrophoresis of a number of hor
Externí odkaz:
https://doaj.org/article/578f14e8ce6141bcb84b9a3b5c546219
Autor:
Thomas A. B. Sanders, Sandra D. O'Dell, Aseel AlSaleh, Wendy L. Hall, Zoitsa Maniou, Fiona Lewis
Publikováno v:
The Journal of Nutrition. 144:267-272
Blood pressure is a heritable determinant of cardiovascular disease (CVD) risk. Recent genome-wide association studies have identified several single-nucleotide polymorphisms (SNPs) associated with blood pressure, including rs1378942 in the c-Src tyr
Autor:
Wendy L. Hall, Thomas A. B. Sanders, Zoitsa Maniou, Sandra D. O'Dell, Aseel AlSaleh, Marina study team, Fiona Lewis, Daria Crepostnaia
Publikováno v:
The Journal of Nutrition. 143:1021-1027
Marine n3 polyunsaturated fatty acids (PUFAs) activate the transcription factor peroxisome proliferator-activated receptor (PPARγ), which modulates the expression of adiponectin. We investigated the interaction of dietary n3 PUFAs with adiponectin g
Autor:
Sandra D. O'Dell, Thomas A. B. Sanders, Aseel AlSaleh, Wendy L. Hall, Fiona Lewis, Zoitsa Maniou, Maryam Al-Hilal
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 2, Pp 542-551 (2013)
Delta-5 and delta-6 desaturases (D5D and D6D) are key enzymes in endogenous synthesis of long-chain PUFAs. In this sample of healthy subjects (n = 310), genotypes of single nucleotide polymorphisms (SNPs) rs174537, rs174561, and rs3834458 in the FADS
Autor:
Sandra D. O'Dell, Cyrus Cooper, Elaine M. Dennison, Avan Aihie Sayer, David I. W. Phillips, Tom R. Gaunt, Patricia J. Briggs, Ian N.M. Day, Holly E. Syddall, Caroline H.D. Fall
Ciliary neurotrophic factor (CNTF) administration reduces weight in leptin-resistant mice via the signalling pathway normally activated by leptin. A G>A null mutation in the CNTF gene results in complete absence of protein. We hypothesised that absen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9c163b8dd6b7249c39e12d6748d8ce
https://ora.ox.ac.uk/objects/uuid:fa6bd539-3dc2-4ae7-8671-9d1debac25d6
https://ora.ox.ac.uk/objects/uuid:fa6bd539-3dc2-4ae7-8671-9d1debac25d6
Autor:
Aseel, AlSaleh, Sandra D, O'Dell, Gary S, Frost, Bruce A, Griffin, Julie A, Lovegrove, Susan A, Jebb, Thomas A B, Sanders, Margaret, Griffin
Background: Adiponectin gene expression is modulated by peroxisome proliferator–activated receptor γ, which is a transcription factor activated by unsaturated fatty acids. Objective: We investigated the effect of the interaction between variants a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ac6187cb29fb6c2096992ab7f26861
https://ora.ox.ac.uk/objects/uuid:7b89e515-5a35-4625-bbdc-e042c87e81bc
https://ora.ox.ac.uk/objects/uuid:7b89e515-5a35-4625-bbdc-e042c87e81bc
Publikováno v:
Loonam, C R, O’Dell, S D, Sharp, P & Mullen, A 2017, ' Conjugated linoleic acid isomers exert differential effects on an adipocyte model of HIV-associated lipodystrophy ', CURRENT HIV RESEARCH, vol. 15, no. 1, pp. 46-55 . https://doi.org/10.2174/1570162X14666161207125948
Background: HIV-associated lipodystrophy is associated with decreased expression of PPAR-γ in adipose tissue. Conjugated linoleic acid (CLA) isomers (cis9, trans11 and trans10, cis12) are putative PPAR-γ agonists, but have not previously been inves