Výsledky vyhledávání - "Sandra Constantin"

Akademický článek

New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile

Autor: Ioana-Mirela Vasincu, Maria Apotrosoaei, Sandra Constantin, Maria Butnaru, Liliana Vereștiuc, Cătălina-Elena Lupușoru, Frederic Buron, Sylvain Routier, Dan Lupașcu, Roxana-Georgiana Taușer, Lenuța Profire

Publikováno v: BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-9 (2021)

Abstract Background Aryl-propionic acid derivatives with ibuprofen as representative drug are very important for therapy, being recommended especially for anti-inflammatory and analgesic effects. On other hand 1,3-thiazolidine-4-one scaffold is an im

Externí odkaz: https://doaj.org/article/91fa028830c14ab09b53ec6e3561c605

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Akademický článek

Chitosan-Based Delivery Systems Loaded with Glibenclamide and Lipoic Acid: Formulation, Characterization, and Kinetic Release Studies

Autor: Luminita-Georgeta Confederat, Iuliana Motrescu, Mihaela Iustina Condurache, Sandra Constantin, Alexandra Bujor, Cristina Gabriela Tuchilus, Lenuta Profire

Publikováno v: Applied Sciences, Vol 10, Iss 21, p 7532 (2020)

Glibenclamide and lipoic acid are two drugs frequently recommended for the management of diabetes mellitus, and so, the development of a new formulation containing both substances has a great benefit in terms of efficiency and compliance, acting also

Externí odkaz: https://doaj.org/article/810cd5da1b6f4d84bb8807557505cd59

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Didactic mediations of professors of Communication: a case study at the Federal University of Bahia

Autor: Popoff, Sandra Constantin

Publikováno v: Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA

Submitted by Sandra Constantin Popoff (contamais1000@gmail.com) on 2022-04-28T13:08:18Z No. of bitstreams: 1 Mediações Didáticas de Professores de Comunicação [TESE POPOFF 2022].pdf: 2007195 bytes, checksum: 3fdb2779f38283bf85b0b60328dde6fc (MD5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::3cffa092a038a031853569dd502fc957
https://repositorio.ufba.br/handle/ri/35139

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Optimization of the Synthesis of Diclofenac Derivatives with Hydrazone Structure and In Vitro Evaluation of the Anti-Inflammatory Potential

Autor: Alin Viorel Focsa, Andreea Teodora Iacob, Loredana Andriescu, Maria Apotrosoaei, Lenuta Profire, Sylvain Routier, Alexandru Sava, Ioana Vasincu, Frédéric Buron, Sandra Constantin

Publikováno v: Revista de Chimie. 71:305-314

The aim of the study was to optimize the synthesis of diclofenac derivative with hydrazones structure in order to obtain higher yields and purity by variation of different parameters such as: ratio between reactants, solvent, catalyst, temperature, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9998213c5fe6b5f5789172acd9d5f7b
https://doi.org/10.37358/rc.20.5.8138

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Design, Synthesis, In Silico and In Vitro Studies for New Nitric Oxide-Releasing Indomethacin Derivatives with 1,3,4-Oxadiazole-2-thiol Scaffold

Autor: Nela Bibire, Florentina Lupașcu, Sylvain Routier, Frédéric Buron, Sandra Constantin, Alexandru Sava, Alin Viorel Focșa, Lenuţa Profire, Alina Panainte

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 7079, p 7079 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13

Starting from indomethacin (IND), one of the most prescribed non-steroidal anti-inflammatory drugs (NSAIDs), new nitric oxide-releasing indomethacin derivatives with 1,3,4-oxadiazole-2-thiol scaffold (NO-IND-OXDs, 8a–p) have been developed as a saf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1543a93fb6927e9886f070b2c3fd81
https://www.mdpi.com/1422-0067/22/13/7079

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Chitosan-Based Delivery Systems Loaded with Glibenclamide and Lipoic Acid: Formulation, Characterization, and Kinetic Release Studies

Autor: Lenuta Profire, Luminita-Georgeta Confederat, Cristina Tuchilus, Sandra Constantin, Iuliana Motrescu, Mihaela Iustina Condurache, Alexandra Bujor

Publikováno v: Applied Sciences, Vol 10, Iss 7532, p 7532 (2020)
Applied Sciences
Volume 10
Issue 21

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaba12792b2cbd73e2ff8f3e66eec23
https://www.mdpi.com/2076-3417/10/21/7532

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Synthesis of [1,3,4]Thiadiazolo[3′,2′:1,2]imidazo[4,5-c]quinolines including Pictet–Spengler Reaction and Exploration of Their C-2 Reactivity through SNAr

Autor: Sandra Constantin, Matthieu Place, Maria Apotrosoaei, Frédéric Buron, Chloé Copin, Ioana Vasincu, Lenuta Profire, Sylvain Routier

Publikováno v: The Journal of Organic Chemistry. 82:13700-13707

This work reports the design of [1,3,4]thiadiazolo[3′,2′:1,2]imidazo[4,5-c]quinolines using a Pictet–Spengler reaction. The scope of the reaction was achieved from 6-(2-aminophenyl)imidazo[2,1-b][1,3,4]thiadiazole derivatives and available alde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b325a995c7e301d06f7334c1fa3d35c
https://doi.org/10.1021/acs.joc.7b02565

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Formulation and Characterization of New Polymeric Systems Based on Chitosan and Xanthine Derivatives with Thiazolidin-4-One Scaffold

Autor: Frédéric Buron, Sylvain Routier, Alexandru Sava, Sandra Constantin, Maria Apotrosoaei, Lenuţa Profire, Florentina Lupașcu, Cristina Tuchilus, Luminița Confederat, Marta Teodora Constantin, Ioana Vasincu

Publikováno v: Materials, Vol 12, Iss 4, p 558 (2019)
Materials
Volume 12
Issue 4

In the past many research studies have focused on the thiazolidine-4-one scaffold, due to the important biological effects associated with its heterocycle. This scaffold is present in the structure of many synthetic compounds, which showed significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3f68b578a4b6274d108b1edbcedeec
https://www.mdpi.com/1996-1944/12/4/558

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Antidiabetic effects and safety profile of chitosan delivery systems loaded with new xanthine-thiazolidine-4-one derivatives: in vivo studies

Autor: Lenuta Profire, Ioana Vasincu, Gabriel Dimitriu, Luminita Confederat, Sandra Constantin, Catalina Elena Lupusoru, Alin Viorel Focsa, Frédéric Buron, Sylvain Routier, Florentina Lupascu, Maria Apotrosoaei

Publikováno v: Journal of Drug Delivery Science and Technology. 60:102091

Based on important biological effects associated with xanthine and thiazolidine-4-one moieties, especially hypoglycemic and antioxidant, new xanthine derivatives with thiazolidine-4-one scaffold (XTDs, 6a-k) have been synthesized and reported by our

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f6fd7b85b062f31ebe4f03f914033f2
https://doi.org/10.1016/j.jddst.2020.102091

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A construção do perfil do professor e a mediação didática lúdica no Ensino Fundamental II

Autor: Sandra Constantin Popoff, Cristina d'Ávila

Publikováno v: Revista entreideias: educação, cultura e sociedade. 7

RESUMO O artigo traz resultados de pesquisa realizada em 2016 com professores que tiveram uma história de vida marcada pela leitura literária e estabelecem mediações de leitura em ambiente escolar no ensino fundamental II. A pesquisa foi realizad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::913d38e39a0d0c7f7df2a42cf91d4044
https://doi.org/10.9771/re.v7i1.22082

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