Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Sandra Citi"'
Publikováno v:
Cells, Vol 12, Iss 15, p 2004 (2023)
Cingulin (CGN) and paracingulin (CGNL1) are cytoplasmic proteins of tight junctions (TJs), where they play a role in tethering ZO-1 to the actomyosin and microtubule cytoskeletons. The role of CGN and CGNL1 in the barrier function of epithelia is not
Externí odkaz:
https://doaj.org/article/83ba493373054e84aec8d6b4ed257a67
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
PLEKHA5, PLEKHA6, and PLEKHA7 (WW-PLEKHAs) are members of the PLEKHA family of proteins that interact with PDZD11 through their tandem WW domains. WW-PLEKHAs contribute to the trafficking and retention of transmembrane proteins, including nectins, Ts
Externí odkaz:
https://doaj.org/article/1b51ff394f3847219f63468f51452a64
Autor:
Martina Rossi, Gabriele Bucci, Dario Rizzotto, Domenico Bordo, Matteo J. Marzi, Margherita Puppo, Arielle Flinois, Domenica Spadaro, Sandra Citi, Laura Emionite, Michele Cilli, Francesco Nicassio, Alberto Inga, Paola Briata, Roberto Gherzi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Several lncRNAs are regulated by TGF-β. Here the authors report that an intergenic lncRNA —EPR— is a component of the TGF-β signaling pathway and controls epithelial cell proliferation by altering transcription and mRNA decay of Cdkn1a. EPR ove
Externí odkaz:
https://doaj.org/article/d6f7e15deb314cbf950c9b2234270de8
Publikováno v:
Cells, Vol 11, Iss 4, p 627 (2022)
Transmembrane proteins of adherens and tight junctions are known targets for viruses and bacterial toxins. The coronavirus receptor ACE2 has been localized at the apical surface of epithelial cells, but it is not clear whether ACE2 is localized at ap
Externí odkaz:
https://doaj.org/article/f23625556fbe4dabba761aa568f8e28e
Autor:
Jimit Shah, Florian Rouaud, Diego Guerrera, Ekaterina Vasileva, Lauren M. Popov, William L. Kelley, Eric Rubinstein, Jan E. Carette, Manuel R. Amieva, Sandra Citi
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2132-2147.e7 (2018)
Summary: We previously identified PLEKHA7 and other junctional proteins as host factors mediating death by S. aureus α-toxin, but the mechanism through which junctions promote toxicity was unclear. Using cell biological and biochemical methods, we n
Externí odkaz:
https://doaj.org/article/1cb104ff748d4600b32198434a057298
Autor:
Anthony J. Mangan, Daniel V. Sietsema, Dongying Li, Jeffrey K. Moore, Sandra Citi, Rytis Prekeris
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Polarisation of epithelial cells causes lumen formation, which is mediated by apical membrane initiation site (AMIS) and FIP5, but how this is regulated is unclear. Here, the authors identify cingulin as a FIP-5 interacting protein, recruiting the Ra
Externí odkaz:
https://doaj.org/article/845014529cdd4857ab83d3e6c1694918
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135442 (2015)
PLEKHA7 is a junctional protein, which participates in a complex that stabilizes E-cadherin at the zonula adhaerens. Since E-cadherin is involved in epithelial morphogenesis, signaling, and tumor progression, we explored PLEKHA7 expression in cancer.
Externí odkaz:
https://doaj.org/article/14de4c6718644d5880074cb4c2f75dc2
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55873 (2013)
The cytoplamic junctional proteins cingulin and paracingulin have been implicated in the regulation of gene expression in different cultured cell models. In renal epithelial MDCK cells, depletion of either protein results in a Rho-dependent increase
Externí odkaz:
https://doaj.org/article/8e4ab20d256442878aed21d1a8b161af
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12207 (2010)
The pleckstrin-homology-domain-containing protein PLEKHA7 was recently identified as a protein linking the E-cadherin-p120 ctn complex to the microtubule cytoskeleton. Here we characterize the expression, tissue distribution and subcellular localizat
Externí odkaz:
https://doaj.org/article/77c2b89145c24dae899881f4474bc47f
Autor:
Florian Rouaud, Wenmao Huang, Arielle Flinois, Kunalika Jain, Ekaterina Vasileva, Thomas Di Mattia, Marine Mauperin, David A.D. Parry, Vera Dugina, Christine Chaponnier, Isabelle Méan, Sylvie Montessuit, Annick Mutero-Maeda, Jie Yan, Sandra Citi
Publikováno v:
Journal of Cell Biology. 222
The mechanisms that regulate the spatial sorting of nonmuscle myosins-2 (NM2) isoforms and couple them mechanically to the plasma membrane are unclear. Here we show that the cytoplasmic junctional proteins cingulin (CGN) and paracingulin (CGNL1) inte