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pro vyhledávání: '"Sandra C. Garrett"'
Autor:
Sandra C. Garrett
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated genes) is a type of prokaryotic immune system that is unique in its ability to provide sequence-specific adaptive protection, which can be updated in response
Externí odkaz:
https://doaj.org/article/fa13d20c79d644d7b54a6fa2b1895379
Autor:
Sandra C. Garrett, Cecile Philippe, Jenny G. Kim, Yunzhou Wei, Katie A. Johnson, Sara Olson, Brenton R. Graveley, Michael P. Terns
Publikováno v:
Journal of Bacteriology.
Streptococcus thermophilus is an important organism for production of cultured dairy foods, but it is susceptible to lytic phages which can lead to failed products. Consequently, mechanisms for phage resistance are an active area of research.
Autor:
Walter T. Woodside, Nikita Vantsev, Ryan J. Catchpole, Sandra C. Garrett, Sara Olson, Brenton R. Graveley, Michael P. Terns
Publikováno v:
RNA. 28:1074-1088
CRISPR-Cas systems are functionally diverse prokaryotic antiviral defense systems, which encompass six distinct types (I–VI) that each encode different effector Cas nucleases with distinct nucleic acid cleavage specificities. By harnessing the uniq
Autor:
Elizabeth A. Watts, Sandra C. Garrett, Ryan J. Catchpole, Landon M. Clark, Brenton R. Graveley, Michael P. Terns
Publikováno v:
Extremophiles
Pyrococcus furiosus is a hyperthermophilic archaeon with three effector CRISPR complexes (types I-A, I-B, and III-B) that each employ crRNAs derived from seven CRISPR arrays. Here, we investigate the CRISPR adaptation response to a newly discovered a
Autor:
Michael P. Terns, Elizabeth A. Watts, Landon Clark, Sandra C. Garrett, Brenton R. Graveley, Masami Shiimori
Publikováno v:
Nucleic Acids Research
CRISPR-Cas adaptive immune systems are used by prokaryotes to defend against invaders like viruses and other mobile genetic elements. Immune memories are stored in the form of ‘spacers’ which are short DNA sequences that are captured from invader
Autor:
Shahar Alon, Sandra C Garrett, Erez Y Levanon, Sara Olson, Brenton R Graveley, Joshua J C Rosenthal, Eli Eisenberg
Publikováno v:
eLife, Vol 4 (2015)
RNA editing by adenosine deamination alters genetic information from the genomic blueprint. When it recodes mRNAs, it gives organisms the option to express diverse, functionally distinct, protein isoforms. All eumetazoans, from cnidarians to humans,
Externí odkaz:
https://doaj.org/article/8c30e23d10bf44a8b235ce30ebf7a6e1
Publikováno v:
Microbiology Resource Announcements
We report here the complete genome sequence of Streptococcus ratti strain JH145. Streptococcus ratti is a cariogenic species of mutans streptococcus that has been isolated from rat and human teeth. The strain JH145, derived from strain BHT-2, is inte
Autor:
Michael P. Terns, Masami Shiimori, Sandra C. Garrett, Brenton R. Graveley, Dwain P. Chambers, Claiborne V.C. Glover
Publikováno v:
Nucleic Acids Research
To acquire CRISPR–Cas immunity against invasive mobile genetic elements, prokaryotes must first integrate fragments of foreign DNA into their genomic CRISPR arrays for use in future invader silencing. Here, we found that the hyperthermophilic archa
Publikováno v:
Nucleic Acids Research
CRISPR–Cas systems provide heritable immunity against viruses by capturing short invader DNA sequences, termed spacers, and incorporating them into the CRISPR loci of the prokaryotic host genome. Here, we investigate DNA elements that control accur
Autor:
E Anne, Hatmaker, Lauren A, Riley, Kaela B, O'Dell, Beth, Papanek, Brenton R, Graveley, Sandra C, Garrett, Yunzhou, Wei, Michael P, Terns, Adam M, Guss
Publikováno v:
Genome Announcements
We report here the complete genome sequence of Streptococcus thermophilus DGCC 7710. S. thermophilus is widely used in industrial dairy production.