Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sandra Bien"'
Autor:
Céline Tolksdorf, Eileen Moritz, Robert Wolf, Ulrike Meyer, Sascha Marx, Sandra Bien-Möller, Ulrike Garscha, Gabriele Jedlitschky, Bernhard H. Rauch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10278 (2022)
Sphingosine-1-phosphate (S1P) is a versatile signaling lipid involved in the regulation of numerous cellular processes. S1P regulates cellular proliferation, migration, and apoptosis as well as the function of immune cells. S1P is generated from sphi
Externí odkaz:
https://doaj.org/article/2d29686402d546d0811a460abe515fdf
Autor:
Carolin Seifert, Ellen Balz, Susann Herzog, Anna Korolev, Sebastian Gaßmann, Heiko Paland, Matthias A. Fink, Markus Grube, Sascha Marx, Gabriele Jedlitschky, Mladen V. Tzvetkov, Bernhard H. Rauch, Henry W. S. Schroeder, Sandra Bien-Möller
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11126 (2021)
Despite comprehensive therapy and extensive research, glioblastoma (GBM) still represents the most aggressive brain tumor in adults. Glioma stem cells (GSCs) are thought to play a major role in tumor progression and resistance of GBM cells to radioch
Externí odkaz:
https://doaj.org/article/84b52da1c50b4d37b01a635ce11459f2
Autor:
Sandra Bien-Möller, Ellen Balz, Susann Herzog, Laura Plantera, Silke Vogelgesang, Kerstin Weitmann, Carolin Seifert, Matthias A. Fink, Sascha Marx, Angela Bialke, Chitra Venugopal, Sheila K. Singh, Wolfgang Hoffmann, Bernhard H. Rauch, Henry W. S. Schroeder
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Patients with glioblastoma multiforme (GBM) are at high risk to develop a relapse despite multimodal therapy. Assumedly, glioma stem cells (GSCs) are responsible for treatment resistance of GBM. Identification of specific GSC markers may help to deve
Externí odkaz:
https://doaj.org/article/218f53324488424fa91fe360416fe654
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2448 (2017)
The multifunctional sphingosine-1-phosphate (S1P) is a lipid signaling molecule and central regulator in the development of several cancer types. In recent years, intriguing information has become available regarding the role of S1P in the progressio
Externí odkaz:
https://doaj.org/article/7b106d275cce41279c64680eb6cae219
Autor:
Tobias Gröβl, Elke Hammer, Sandra Bien-Möller, Anja Geisler, Sandra Pinkert, Carsten Röger, Wolfgang Poller, Jens Kurreck, Uwe Völker, Roland Vetter, Henry Fechner
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92188 (2014)
In failing rat hearts, post-transcriptonal inhibition of phospholamban (PLB) expression by AAV9 vector-mediated cardiac delivery of short hairpin RNAs directed against PLB (shPLBr) improves both impaired SERCA2a controlled Ca2+ cycling and contractil
Externí odkaz:
https://doaj.org/article/24d6328119ec46e1af5b1e45c5db6072
Autor:
Sebastian, Lehmann, Sandra, Bien-Möller, Sascha, Marx, Sander, Bekeschus, Henry W S, Schroeder, Alexander, Mustea, Matthias B, Stope
Publikováno v:
Anticancer Research. 43:7-18
Glioblastoma (GBM) is the most common and most lethal type of cancer of the central nervous system in adults. Despite aggressive treatment, which is based on surgical resection, if possible, followed by radiation and chemotherapy, a high recurrence r
Autor:
Sandra Bien-Möller, Henry W.S. Schroeder, Bernhard H. Rauch, Wolfgang Hoffmann, Angela Bialke, Kerstin Weitmann, Silke Vogelgesang, Markus Grube, Susann Herzog, Heiko Paland, Matthias A. Fink
Purpose:Apoptotic dysregulation, redox adaptive mechanisms, and resilience to hypoxia are major causes of glioblastoma (GBM) resistance to therapy. Commonly known as crucial factors in energy metabolism, OCTN2 (SLC22A5) and its substrate L-carnitine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c0d11a9243b176e0b6ac9be2ba1f18
https://doi.org/10.1158/1078-0432.c.6527738
https://doi.org/10.1158/1078-0432.c.6527738
Autor:
Sandra Bien-Möller, Henry W.S. Schroeder, Bernhard H. Rauch, Wolfgang Hoffmann, Angela Bialke, Kerstin Weitmann, Silke Vogelgesang, Markus Grube, Susann Herzog, Heiko Paland, Matthias A. Fink
Expression and survival analyses of CPT1A and CPT1C in GBM specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b08599f9604aa85ca5794539ad8068
https://doi.org/10.1158/1078-0432.22470941
https://doi.org/10.1158/1078-0432.22470941
Autor:
Sascha Marx, Fabian Wilken, Lea Miebach, Mikael Ispirjan, Frederik Kinnen, Sebastian Paul, Sandra Bien-Möller, Eric Freund, Jörg Baldauf, Steffen Fleck, Nikolai Siebert, Holger Lode, Andreas Stahl, Bernhard H. Rauch, Stephan Singer, Christoph Ritter, Henry W. S. Schroeder, Sander Bekeschus
Publikováno v:
Cancers; Volume 14; Issue 23; Pages: 5751
Glioblastoma is the most common and lethal primary brain malignancy that almost inevitably recurs as therapy-refractory cancer. While the success of immune checkpoint blockade (ICB) revealed the immense potential of immune-targeted therapies in sever
Autor:
Bernhard H. Rauch, Susann Herzog, Henry W. S. Schroeder, Angela Bialke, Silke Vogelgesang, Matthias A. Fink, Heiko Paland, Kerstin Weitmann, Markus Grube, Wolfgang Hoffmann, Sandra Bien-Möller
Publikováno v:
Clinical Cancer Research. 25:2874-2886
Purpose: Apoptotic dysregulation, redox adaptive mechanisms, and resilience to hypoxia are major causes of glioblastoma (GBM) resistance to therapy. Commonly known as crucial factors in energy metabolism, OCTN2 (SLC22A5) and its substrate L-carnitine