Výsledky vyhledávání - "Sandra Bernat-Fabre"

Akademický článek

Inducible degradation of the Drosophila Mediator subunit Med19 reveals its role in regulating developmental but not constitutively-expressed genes.

Autor: Denis Jullien, Emmanuelle Guillou, Sandra Bernat-Fabre, Adeline Payet, Henri-Marc G Bourbon, Muriel Boube

Publikováno v: PLoS ONE, Vol 17, Iss 11, p e0275613 (2022)

The multi-subunit Mediator complex plays a critical role in gene expression by bridging enhancer-bound transcription factors and the RNA polymerase II machinery. Although experimental case studies suggest differential roles of Mediator subunits, a co

Externí odkaz: https://doaj.org/article/ee12978a4fd347a5b1720d033303d601

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Tissue-specific enhancer repression through molecular integration of cell signaling inputs.

Autor: Luis Humberto Mojica-Vázquez, Mikhail H Benetah, Aissette Baanannou, Sandra Bernat-Fabre, Bart Deplancke, David L Cribbs, Henri-Marc Bourbon, Muriel Boube

Publikováno v: PLoS Genetics, Vol 13, Iss 4, p e1006718 (2017)

Drosophila leg morphogenesis occurs under the control of a relatively well-known genetic cascade, which mobilizes both cell signaling pathways and tissue-specific transcription factors. However, their cross-regulatory interactions, deployed to refine

Externí odkaz: https://doaj.org/article/f7c0b5bc6a1143ada089daef13085055

Zobrazit plný text záznamu

Akademický článek

Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19.

Autor: Muriel Boube, Bruno Hudry, Clément Immarigeon, Yannick Carrier, Sandra Bernat-Fabre, Samir Merabet, Yacine Graba, Henri-Marc Bourbon, David L Cribbs

Publikováno v: PLoS Genetics, Vol 10, Iss 5, p e1004303 (2014)

Hox genes in species across the metazoa encode transcription factors (TFs) containing highly-conserved homeodomains that bind target DNA sequences to regulate batteries of developmental target genes. DNA-bound Hox proteins, together with other TF par

Externí odkaz: https://doaj.org/article/6cf71a12860b445a90ba3a0cddc92f60

Zobrazit plný text záznamu

Tissue-specific versus pleiotropic enhancers within thebric-a-bractandem gene duplicates display differential regulatory activity and evolutionary conservation

Autor: Emmanuelle Guillou, Muriel Boube, Loubiere, Giacomo Cavalli, Mojica-Vazquez Lh, Henri-Marc Bourbon, Benetah Mh, Baanannou A, Sandra Bernat-Fabre, Frédéric Bantignies

During animal evolution, de novo emergence and modifications of pre-existing transcriptional enhancers have contributed to biological innovations, by implementing gene regulatory networks. TheDrosophila melanogaster bric-a-brac(bab) complex, comprisi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0f4325b8993c9d81c9053657706457c
https://doi.org/10.1101/2021.03.25.436949

Zobrazit plný text záznamu

A shared ancient enhancer element differentially regulates the bric-a-brac tandem gene duplicates in the developing Drosophila leg

Autor: Henri-Marc G. Bourbon, Mikhail H. Benetah, Emmanuelle Guillou, Luis Humberto Mojica-Vazquez, Aissette Baanannou, Sandra Bernat-Fabre, Vincent Loubiere, Frédéric Bantignies, Giacomo Cavalli, Muriel Boube

Publikováno v: PLOS Genetics. 18:e1010083

Gene duplications and transcriptional enhancer emergence/modifications are thought having greatly contributed to phenotypic innovations during animal evolution. Nevertheless, little is known about how enhancers evolve after gene duplication and how r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9c8f0c39c062922c98d17b64cafa54
https://doi.org/10.1371/journal.pgen.1010083

Zobrazit plný text záznamu

Mediator complex subunit Med19 binds directly GATA DNA-binding zinc finger and functions with Med1 in GATA-driven gene regulationin vivo

Autor: Marie Couralet, Clément Immarigeon, Sandra Bernat-Fabre, Alexis Verger, Adeline Payet, Muriel Boube, Emmanuelle Guillou, Henri-Marc Bourbon, Elodie Prince, Vincent Villeret, Didier Monté, Mohamed A. Benmedjahed

The evolutionarily-conserved multiprotein Mediator complex (MED) serves as an interface between DNA-bound transcription factors (TFs) and the RNA Polymerase II machinery. It has been proposed that each TF interacts with a dedicated MED subunit to ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576040ff0389069d879bbf215e26d9f0
https://doi.org/10.1101/2020.04.03.023895

Zobrazit plný text záznamu

Mediator complex subunit Med19 binds directly GATA transcription factors and is required with Med1 for GATA-driven gene regulation in vivo

Autor: Adeline Payet, Muriel Boube, Alexis Verger, Emmanuelle Guillou, Mohamed A. Benmedjahed, Clément Immarigeon, Marie Couralet, Didier Monté, Elodie Prince, Henri-Marc Bourbon, Vincent Villeret, Sandra Bernat-Fabre

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2020, 295 (39), pp.13617-13629. ⟨10.1074/jbc.RA120.013728⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (39), pp.13617-13629. ⟨10.1074/jbc.RA120.013728⟩
J Biol Chem

International audience; The evolutionarily conserved multiprotein Mediator complex (MED) serves as an interface between DNA-bound transcription factors (TFs) and the RNA Pol II machinery. It has been proposed that each TF interacts with a dedicated M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c64a199a135ae15bdf2e462a699a4a4
https://hal.science/hal-02987861v2/file/1-s2.0-S0021925817500174-main.pdf

Zobrazit plný text záznamu

Drosophila Mediator Subunit Med1 Is Required for GATA-Dependent Developmental Processes: Divergent Binding Interfaces for Conserved Coactivator Functions

Autor: Vanessa Gobert, David L. Cribbs, Adeline Payet, Muriel Boube, Sandra Bernat-Fabre, Henri-Marc Bourbon, Clément Immarigeon, Benoit Augé, Christian Faucher, Lucas Waltzer, Marc Haenlin

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2019, 39 (7), pp.e1009641. ⟨10.1128/MCB.00477-18⟩
Molecular and Cellular Biology, American Society for Microbiology, 2019, 39 (7), ⟨10.1128/MCB.00477-18⟩
Molecular and Cellular Biology, 2019, 39 (7), pp.e1009641. ⟨10.1128/MCB.00477-18⟩

International audience; DNA-bound transcription factors (TFs) governing developmental gene regulation have been proposed to recruit polymerase II machinery at gene promoters through specific interactions with dedicated subunits of the evolutionarily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1b81c111bdbe2bfdbd9b583453e985
https://hal.archives-ouvertes.fr/hal-03365096

Zobrazit plný text záznamu

Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19

Autor: Yannick Carrier, David L. Cribbs, Sandra Bernat-Fabre, Muriel Boube, Clément Immarigeon, Samir Merabet, Yacine Graba, Henri-Marc Bourbon, Bruno Hudry

Publikováno v: PLoS Genetics, Vol 10, Iss 5, p e1004303 (2014)
PLoS Genetics
PLoS Genetics, Public Library of Science, 2014, 10 (5), pp.e1004303. ⟨10.1371/journal.pgen.1004303⟩
PLoS Genetics, 2014, 10 (5), pp.e1004303. ⟨10.1371/journal.pgen.1004303⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043f21da961ed3b096e9c7056ce4c978
http://europepmc.org/articles/PMC4006704?pdf=render

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání