Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome

Autor: Debora Bresciani, Elisabetta Grillo, Francesco Missale, Benedetta Zanetti, Claudio Simeone, Sara Licini, Luca Cristinelli, Sandra Belotti, Luisa Benerini Gatta, Stefano Calza, Szeman Ruby Chan, Mattia Bugatti, William Vermi, Roberto Ronca, Emanuele Giurisato, Regina Tardanico, Laura Melocchi, Silvia Lonardi

Publikováno v: Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1219 (2019)
Gatta, L B, Melocchi, L, Bugatti, M, Missale, F, Lonardi, S, Zanetti, B, Cristinelli, L, Belotti, S, Simeone, C, Ronca, R, Grillo, E, Licini, S, Bresciani, D, Tardanico, R, Chan, S R, Giurisato, E, Calza, S & Vermi, W 2019, ' Hyper-activation of STAT3 sustains progression of non-papillary basal-type bladder cancer via FOSL1 regulome ', Cancers, vol. 11, no. 9, 1219 . https://doi.org/10.3390/cancers11091219

Urothelial bladder cancer (UBC) are classified into luminal and basal subtypes showing distinct molecular features and clinical behaviour. Recent in silico data have proposed the activation on the Signal Transducer and Activator of Transcription 3 (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4655bdaf86519abebb493d5a788fa799

The impact of completeness of last transurethral resection of bladder tumors on the outcomes of radical cystectomy

Autor: Sandra Belotti, Stefania Zamboni, Alessandro Antonelli, Agostino Mattei, Philipp Baumeister, Andrea Salonia, Luca Cristinelli, Alberto Briganti, Claudio Simeone, Andrea Gallina, Renzo Colombo, Francesco Montorsi, Marco Moschini

Purpose: To evaluate the role of a complete transurethral resection of bladder tumors (c-TURBT) on oncological outcomes after radical cystectomy (RC) and its relationship with adverse pathological features. Methods: We retrospectively analyzed data o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f063c48c52da1bd6819849df3726bf07
http://springerlink.metapress.com/app/home/journal.asp?wasp=m1gnpkuglrd1e6tvxceg&referrer=parent&backto=browsepublicationsresults,515,533

Prognostic role of delay before radical cystectomy: Retrospective analysis of a single-center cohort with 376 patients

Autor: Alessandro Antonelli, Stefania Zamboni, Marco Lattarulo, Maria Furlan, Claudio Simeone, Carlotta Palumbo, Luca Cristinelli, Sandra Belotti, Maria Cristina Marconi

BACKGROUND According to International Guidelines radical cystectomy (RC) should not be delayed over 90 days to prevent the risk of intercurrent progression and worse survival. Nevertheless, such a recommendation relies on a few retrospective studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c009b7238061def2b1ac2cb89598db9
http://hdl.handle.net/11379/513960

Tumor Infiltrating Neutrophils Are Enriched in Basal-Type Urothelial Bladder Cancer

Autor: Elena Caveggion, Matilde Monti, Sandra Belotti, Claudio Simeone, Luca Cristinelli, Luisa Benerini Gatta, Giulio Eugenio Mandelli, Stefano Calza, William Vermi, Laura Melocchi, Patrizia Scapini, Mattia Bugatti, Francesco Missale, Debora Bresciani, Elisa Roca

Publikováno v: Cells
Cells, Vol 9, Iss 2, p 291 (2020)
Volume 9
Issue 2

Background: Urothelial bladder cancers (UBCs) are distinct in two main molecular subtypes, namely basal and luminal type. Subtypes are also diverse in term of immune contexture, providing a rationale for patient selection to immunotherapy. Methods: B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd98b90c470fe3cb8eb23d3626450fb
https://doi.org/10.3390/cells9020291

[Differences in morbidity of neobladder versus ileal conduit: a matched pair analysis on 134 patients]

Autor: Alessandro Antonelli, Luca Cristinelli, Sandra Belotti, Stefania Zamboni, Claudio Simeone, Vincenzo De Luca

Publikováno v: Urologia. 82(2)

Objective The objective of this study is to evaluate whether performing an ileal conduit (IC) versus a neobladder (NB) during radical cystectomy (RC) can play a role on the morbidity of the surgical procedure. Materials and Methods At our institution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fff21e8e26ffbe65141188853ee711
https://pubmed.ncbi.nlm.nih.gov/27660848