Výsledky vyhledávání - "Sandra Autran"

Akademický článek

Autor: Bowen Dempsey, Selvee Sungeelee, Phillip Bokiniec, Zoubida Chettouh, Séverine Diem, Sandra Autran, Evan R. Harrell, James F. A. Poulet, Carmen Birchmeier, Harry Carey, Auguste Genovesio, Simon McMullan, Christo Goridis, Gilles Fortin, Jean-François Brunet

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Orofacial movements for feeding can be triggered, coordinated and rhythmically organised at the level of the brainstem. Here, the authors show two nuclei can organise the stereotyped movements for ingesting fluids in mammals, these neuronal groups ar

Externí odkaz: https://doaj.org/article/83f986e85b8244b2abbabd0c7d2789df

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Akademický článek

The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2

Autor: Pierre-Louis Ruffault, Fabien D'Autréaux, John A Hayes, Marc Nomaksteinsky, Sandra Autran, Tomoyuki Fujiyama, Mikio Hoshino, Martin Hägglund, Ole Kiehn, Jean-François Brunet, Gilles Fortin, Christo Goridis

Publikováno v: eLife, Vol 4 (2015)

Maintaining constant CO2 and H+ concentrations in the arterial blood is critical for life. The principal mechanism through which this is achieved in mammals is the respiratory chemoreflex whose circuitry is still elusive. A candidate element of this

Externí odkaz: https://doaj.org/article/be6e0678773e4ee880644e9459d90648

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An executive center for the intake of liquids

Autor: Sandra Autran, Séverine Diem, Christo Goridis, Bowen Dempsey, Auguste Genovesio, James F.A. Poulet, Selvee Sungeelee, Jean-François Brunet, Simon McMullan, Philip Bokiniec, Harry Carrey, Gilles Fortin, Carmen Birchmeier, Zoubida Chettouh, Evan R. Harrell

It has long been known that orofacial movements for feeding can be triggered, coordinated, and often rhythmically organized at the level of the brainstem, without input from higher centers. We uncover two nuclei that can organize the movements for in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aaf88edf6c4e3c19e5986c3495763fea
https://doi.org/10.1101/2021.07.02.450862

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Abnormal inspiratory depth in Phox2a haploinsufficient mice

Autor: Ludovic Wrobel, Jean Champagnat, Fabrice Chatonnet, M. Ogier, Sandra Autran, Valérie Mézières, C. Taeron, Muriel Thoby-Brisson, Heather McLean

Publikováno v: Neuroscience. 145:384-392

Mutations of genes encoding Phox2a or Phox2b transcription factors induce modifications of different brainstem neuronal networks. Such modifications are associated with defects in breathing behavior at birth. In particular, an abnormal breathing freq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d908cfb9f7d8e5bac5509579efbc1bd4
https://doi.org/10.1016/j.neuroscience.2006.11.055

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Author response: The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2

Autor: Sandra Autran, Pierre-Louis Ruffault, Tomoyuki Fujiyama, Christo Goridis, Fabien D'Autréaux, Ole Kiehn, Gilles Fortin, Jean-François Brunet, Martin Hägglund, John A. Hayes, Mikio Hoshino, Marc Nomaksteinsky

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08b95369a4892160ecf93953b1e90dc6
https://doi.org/10.7554/elife.07051.017

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Emergence of sigh rhythmogenesis in the embryonic mouse

Autor: Sandra Autran, John Simmers, Gilles Fortin, Muriel Thoby-Brisson, Coralie Chapuis

Publikováno v: The Journal of Physiology
The Journal of Physiology, Wiley, 2014, 592 (Pt 10), pp.2169-81. ⟨10.1113/jphysiol.2013.268730⟩

International audience; In mammals, eupnoeic breathing is periodically interrupted by spontaneous augmented breaths (sighs) that include a larger-amplitude inspiratory effort, typically followed by a post-sigh apnoea. Previous in vitro studies in new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb21a751c8b253a7af51940545aa0a8
https://pubmed.ncbi.nlm.nih.gov/24591570

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The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues

Autor: Peter Lorenz, Gaiping Wen, Dirk Koczan, Yixue Li, Sabine Dietmann, Guohui Ding, H.-J. Thiesen, Marie Françoise Rousseau-Merck, Sophie Gad, Sandra Autran, Thomas Wilhelm

Publikováno v: BMC Genomics
BMC Genomics, BioMed Central, 2010, 11 (1), pp.206. ⟨10.1186/1471-2164-11-206⟩
BMC Genomics, BioMed Central, 2010, 11 (1), pp.206. 〈10.1186/1471-2164-11-206〉
BMC Genomics, Vol 11, Iss 1, p 206 (2010)
BMC Genomics 11:206 (2010)

Background Expansion of multi-C2H2 domain zinc finger (ZNF) genes, including the Krüppel-associated box (KRAB) subfamily, paralleled the evolution of tetrapodes, particularly in mammalian lineages. Advances in their cataloging and characterization s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914fd4fb4ae07a4621035c3f2a5dc59b
https://doi.org/10.1186/1471-2164-11-206

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Brain-derived neurotrophic factor enhances fetal respiratory rhythm frequency in the mouse preBötzinger complex in vitro

Autor: Sandra Autran, Nathalie Dehorter, Gilles Fortin, Muriel Thoby-Brisson, Julien Bouvier, David M. Katz, Jean Champagnat

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2008, 28 (3), pp.510-20. ⟨10.1111/j.1460-9568.2008.06345.x⟩

International audience; Brain-derived neurotrophic factor (BDNF) is required during the prenatal period for normal development of the respiratory central command; however, the underlying mechanisms remain unknown. To approach this issue, the present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b1aea6086a50fe955d158f34d23c5a
https://hal.archives-ouvertes.fr/hal-02394544

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The pre-Bötzinger oscillator in the mouse embryo

Autor: Gilles Fortin, Carine Vias, Muriel Thoby-Brisson, Jean Champagnat, Caroline Borday, Sandra Autran

Publikováno v: Journal of physiology, Paris. 100(5-6)

Studies of the sites and mechanisms involved in mammalian respiratory rhythm generation point to two clusters of rhythmic neurons forming a coupled oscillator network within the brainstem. The location of these oscillators, the pre-Botzinger complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1308ade6f30e32c53edf32942d035b08
https://pubmed.ncbi.nlm.nih.gov/17628453

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Acute role of the brain-derived neurotrophic factor (BDNF) on the respiratory neural network activity in mice in vitro

Autor: Sandra Autran, Julien Bouvier, Muriel Thoby-Brisson, Gilles Fortin, Jean Champagnat

Publikováno v: Journal of Physiology-Paris
Journal of Physiology-Paris, Elsevier, 2007, 100 (5-6), pp.290-6. ⟨10.1016/j.jphysparis.2007.05.008⟩

In humans, several pathologies are associated with disturbances of the respiratory control, some of them including alteration in the brain-derived neurotrophic factor (BDNF) signalling pathway. BDNF has long been known as a neurotrophic factor involv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ffbd837b34e20514bba93a2f99aceb
https://hal.archives-ouvertes.fr/hal-02394562

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