Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Sandra Aung"'
Autor:
Joseph I. Clark, Jatinder Singh, Marc S. Ernstoff, Christopher D. Lao, Lawrence E. Flaherty, Theodore F. Logan, Brendan Curti, Sanjiv S. Agarwala, Bret Taback, Lee Cranmer, Jose Lutzky, Theresa L. Luna, Sandra Aung, David H. Lawson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)
Abstract Background Preclinical studies suggest that BRAF inhibitors enhance anti-tumor immunity and antigen presentation. Combination BRAF inhibition with immunotherapy is an appealing therapeutic approach. We sequenced vemurafenib with HD IL-2 in p
Externí odkaz:
https://doaj.org/article/5cdc7070ed8046e696ecf169baa8612b
Autor:
Rachel E. Sanborn, Helen J. Ross, Sandra Aung, Anupama Acheson, Tarsem Moudgil, Sachin Puri, Traci Hilton, Brenda Fisher, Todd Coffey, Christopher Paustian, Michael Neuberger, Edwin Walker, Hong-Ming Hu, Walter J. Urba, Bernard A. Fox
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-14 (2017)
Abstract Background Tumor-derived autophagosome vaccines (DRibbles) have the potential to broaden immune response to poorly immunogenic tumors. Methods Autologous vaccine generated from tumor cells harvested from pleural effusions was administered to
Externí odkaz:
https://doaj.org/article/51a617bc9e0947b2b40212ed699e06aa
Autor:
Rieneke van de Ven, Traci L. Hilton, Hong-Ming Hu, Christopher J. Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter J. Urba, Brendan D. Curti, Sandra Aung, Bernard A. Fox
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
The immune system plays an essential role in eradicating cancer in concert with various treatment modalities. In the absence of autologous tumor material, no standardized method exists to assess T cell responses against the many antigens that may ser
Externí odkaz:
https://doaj.org/article/15aac23d293c4430b29aebe45cba10a7
Autor:
Howard L. Kaufman, Michael K. Wong, Gregory A. Daniels, David F. McDermott, Sandra Aung, James N. Lowder, Michael A. Morse
Publikováno v:
Journal of Personalized Medicine, Vol 4, Iss 1, Pp 52-64 (2014)
Registries evaluating un-randomized patients have provided valuable information with respect to a therapy’s utility, treatment practices, and evolution over time. While immunotherapy for cancer has been around for more than three decades, data coll
Externí odkaz:
https://doaj.org/article/f594a5b7baa546769787ce5d1c773f60
Autor:
Sandra Aung, Sigrun Hallmeyer, David F. McDermott, Joseph I. Clark, Howard L. Kaufman, Gregory A. Daniels, Sapna P. Patel, John M. Kirkwood, Ryan J. Sullivan, Marc S. Ernstoff, Brendan D. Curti, Elizabeth I. Buchbinder, Rene Gonzalez, John M. Richart, Anasuya Gunturi, Jessica Perritt, Janice Dutcher, Girald P. Miletello, Joe Lutzky, Michael A. Morse
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)
Background High dose interleukin-2 (HD IL-2) can induce durable responses in a subset of patients leading to long-term survival. Immune checkpoint blockade (ICB) has demonstrated similarly durable responses in a larger proportion of patients. However
Externí odkaz:
https://doaj.org/article/44e74afcb6e54cb58b9c7f23eb3b71b5
Autor:
Daniel C. Cho, Michael E. Hurwitz, Chantale Bernatchez, Yijie Liao, Ernesto Iacucci, Ahsan Rizwan, Christie Fanton, Sandra Aung, Ute Hoch, Alison L. Hannah, Jonathan Zalevsky, Mary A. Tagliaferri, Brendan D. Curti, Scott S. Tykodi, Mario Sznol, Scott N. Gettinger, Harriet M. Kluger, Cara Haymaker, Vassiliki Papadimitrakopoulou, Patrick Hwu, Salah-Eddine Bentebibel, Nizar M. Tannir, Adi Diab
This single-arm, phase I dose-escalation trial (NCT02983045) evaluated bempegaldesleukin (NKTR-214/BEMPEG), a CD122-preferential IL2 pathway agonist, plus nivolumab in 38 patients with selected immunotherapy-naïve advanced solid tumors (melanoma, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d9b8ad447190ee9c1740fd458386d6
https://doi.org/10.1158/2159-8290.c.6547937.v1
https://doi.org/10.1158/2159-8290.c.6547937.v1
Autor:
Adi Diab, Mario Sznol, Nizar M. Tannir, Brendan D. Curti, Patrick Hwu, Sandra Aung, Christie Fanton, Ute Hoch, Jonathan Zalevsky, Mary A. Tagliaferri, Michael T. Tetzlaff, Harriet M. Kluger, Courtney W. Hudgens, Cara Haymaker, Chantale Bernatchez, Michael E. Hurwitz, Salah-Eddine Bentebibel
NKTR-214 (bempegaldesleukin) is a novel IL2 pathway agonist, designed to provide sustained signaling through heterodimeric IL2 receptor βγ to drive increased proliferation and activation of CD8+ T and natural killer cells without unwanted expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a901caa74c185ea40858f0a92cea503c
https://doi.org/10.1158/2159-8290.c.6548036.v1
https://doi.org/10.1158/2159-8290.c.6548036.v1
Autor:
Daniel C. Cho, Michael E. Hurwitz, Chantale Bernatchez, Yijie Liao, Ernesto Iacucci, Ahsan Rizwan, Christie Fanton, Sandra Aung, Ute Hoch, Alison L. Hannah, Jonathan Zalevsky, Mary A. Tagliaferri, Brendan D. Curti, Scott S. Tykodi, Mario Sznol, Scott N. Gettinger, Harriet M. Kluger, Cara Haymaker, Vassiliki Papadimitrakopoulou, Patrick Hwu, Salah-Eddine Bentebibel, Nizar M. Tannir, Adi Diab
Consolidated supplementary appendix: tables, figures, text plus legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18296821a0fd4a3f57f085659726850a
https://doi.org/10.1158/2159-8290.22535747.v1
https://doi.org/10.1158/2159-8290.22535747.v1
Autor:
Adi Diab, Mario Sznol, Nizar M. Tannir, Brendan D. Curti, Patrick Hwu, Sandra Aung, Christie Fanton, Ute Hoch, Jonathan Zalevsky, Mary A. Tagliaferri, Michael T. Tetzlaff, Harriet M. Kluger, Courtney W. Hudgens, Cara Haymaker, Chantale Bernatchez, Michael E. Hurwitz, Salah-Eddine Bentebibel
Supplementary Figures, Tables, and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3feb14f936bdc8c827175965516fc153
https://doi.org/10.1158/2159-8290.22536062.v1
https://doi.org/10.1158/2159-8290.22536062.v1
Autor:
Hong-Ming Hu, Walter J. Urba, Bernard A. Fox, Daniel Haley, Sandra Aung, Zhihua Cui, Puiyi Pang, Li-Xin Wang, Yuhuan Li
PDF file - 613K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fa8a0864ef36e0b13f969b8f2042c4
https://doi.org/10.1158/1078-0432.22445027.v1
https://doi.org/10.1158/1078-0432.22445027.v1