Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sandra Arriens"'
Autor:
Sabine Specht, Kenneth M Pfarr, Sandra Arriens, Marc P Hübner, Ute Klarmann-Schulz, Marianne Koschel, Sonja Sternberg, Coralie Martin, Louise Ford, Mark J Taylor, Achim Hoerauf
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006116 (2018)
Filarial parasites can be targeted by antibiotic treatment due to their unique endosymbiotic relationship with Wolbachia bacteria. This finding has led to successful treatment strategies in both, human onchocerciasis and lymphatic filariasis. A 4-6 w
Externí odkaz:
https://doaj.org/article/6980e7b8ae6245a286ea69f8f6cf2598
Autor:
Ute Klarmann-Schulz, Sabine Specht, Alexander Yaw Debrah, Linda Batsa, Nana Kwame Ayisi-Boateng, Jubin Osei-Mensah, Yusif Mubarik, Peter Konadu, Arcangelo Ricchiuto, Rolf Fimmers, Sandra Arriens, Bettina Dubben, Louise Ford, Mark Taylor, Achim Hoerauf
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 1, p e0005156 (2017)
The search for new macrofilaricidal drugs against onchocerciasis that can be administered in shorter regimens than required for doxycycline (DOX, 200mg/d given for 4-6 weeks), identified minocycline (MIN) with superior efficacy to DOX. Further reduct
Externí odkaz:
https://doaj.org/article/7e05df65a5f2493cba57b00fb500101a
Autor:
Tayseer Elamin Mohamed Elfaki, Kathrin Arndts, Anna Wiszniewsky, Manuel Ritter, Ibtisam A Goreish, Misk El Yemen A Atti El Mekki, Sandra Arriens, Kenneth Pfarr, Rolf Fimmers, Mike Doenhoff, Achim Hoerauf, Laura E Layland
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 5, p e0004629 (2016)
BACKGROUND:In the Sudan, Schistosoma mansoni infections are a major cause of morbidity in school-aged children and infection rates are associated with available clean water sources. During infection, immune responses pass through a Th1 followed by Th
Externí odkaz:
https://doaj.org/article/814b43ba1681432790f344fec0a5689c
Autor:
Gnatoulma Katawa, Laura E Layland, Alex Y Debrah, Charlotte von Horn, Linda Batsa, Alexander Kwarteng, Sandra Arriens, David W Taylor, Sabine Specht, Achim Hoerauf, Tomabu Adjobimey
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 1, p e3414 (2015)
Clinical manifestations in onchocerciasis range from generalized onchocerciasis (GEO) to the rare but severe hyperreactive (HO)/sowda form. Since disease pathogenesis is associated with host inflammatory reactions, we investigated whether Th17 respon
Externí odkaz:
https://doaj.org/article/f2da924f6cba47eaa0e98b3bbc948e8c
Autor:
Simone Kann, Thomas Dandekar, Meik Kunz, Jose J. Crespo, Jürgen Sievertsen, Sandra Arriens, Aristides Loperena, Jessica Hansen
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 1517, p 1517 (2020)
Volume 9
Issue 5
Journal of Clinical Medicine, Vol 9, Iss 1517, p 1517 (2020)
Volume 9
Issue 5
Background: Chagas disease (CD) is a major burden in Latin America, expanding also to non-endemic countries. A gold standard to detect the CD causing pathogen Trypanosoma cruzi is currently not available. Existing real time polymerase chain reactions
Autor:
Mark J. Taylor, Marianne Koschel, Ute Klarmann-Schulz, Sonja Sternberg, Louise Ford, Coralie Martin, Sabine Specht, Achim Hoerauf, Sandra Arriens, Kenneth Pfarr, Marc P. Hübner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006116 (2018)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2018, 12 (1), pp.e0006116. ⟨10.1371/journal.pntd.0006116⟩
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2018, 12 (1), pp.e0006116. ⟨10.1371/journal.pntd.0006116⟩
Filarial parasites can be targeted by antibiotic treatment due to their unique endosymbiotic relationship with Wolbachia bacteria. This finding has led to successful treatment strategies in both, human onchocerciasis and lymphatic filariasis. A 4–6
Autor:
Julia M. Sattler, Sabine Specht, Ann-Kristin Mueller, Michael Famulok, Simon Gottwalt, Kenneth Pfarr, Christian S. Lentz, Silke Strassel, Achim Hoerauf, Jeffrey S. Hannam, Victoria S. Halls, Martina Fendler, Sandra Arriens
Publikováno v:
Antimicrobial Agents and Chemotherapy
wALADin1 benzimidazoles are specific inhibitors of δ-aminolevulinic acid dehydratase from Wolbachia endobacteria of filarial nematodes. We report that wALADin1 and two derivatives killed blood stage Plasmodium falciparum in vitro (50% inhibitory con
Autor:
Laura E. Layland, Kathrin Arndts, Anna Wiszniewsky, Mike Doenhoff, Misk El Yemen A. Atti El Mekki, Manuel Ritter, Tayseer Elamin Mohamed Elfaki, Rolf Fimmers, Achim Hoerauf, Sandra Arriens, Ibtisam A. Goreish, Kenneth Pfarr
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 5, p e0004629 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background In the Sudan, Schistosoma mansoni infections are a major cause of morbidity in school-aged children and infection rates are associated with available clean water sources. During infection, immune responses pass through a Th1 followed by Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2a0acf2e594329efc93919b207e9dc
Autor:
Philip Rosenstock, Achim Hoerauf, Kenneth Pfarr, Ingrid Reiter-Owona, Sandra Arriens, Claudia Rehkaemper-Schaefer
Publikováno v:
Parasitology Research
The sensitivity of a K39 ELISA (Leishmania IgG, Virion/Serion) for the detection of antibodies in patients with imported leishmaniasis was compared with an immunofluorescence assay (IFA), which was applied as “golden standard”. The retrospective
Autor:
Frank Brombacher, Bernhard Fleischer, Volker Heussler, Michael Saeftel, Paul Racz, Sandra Arriens, Achim Hoerauf, Andreas Krueger
Publikováno v:
Infection and Immunity. 72:322-331
BALB/c interleukin-4 (IL-4−/−) or IL-4 receptor-α (IL-4rα−/−) knockout (KO) mice were used to assess the roles of the IL-4 and IL-13 pathways during infections with the blood or liver stages of plasmodium in murine malaria. Intraperitoneal