Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Sandra Andorf"'
Autor:
Shweta Mahajan, Aria Alexander, Zachary Koenig, Nicholas Saba, Nina Prasanphanich, David A. Hildeman, Claire A. Chougnet, Emily DeFranco, Sandra Andorf, Tamara Tilburgs
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
Maternal decidual CD8+ T cells must integrate the antithetical demands of providing immunity to infection while maintaining immune tolerance for fetal and placental antigens. Human decidual CD8+ T cells were shown to be highly differentiated memory T
Externí odkaz:
https://doaj.org/article/781060653b01409aa72fd46062791775
Autor:
Amanda R. Tursi, Nicholas K. Saba, Diane Dunham, Monali Manohar, Rachel L. Peters, Richard Saffery, Jennifer J. Koplin, Kari C. Nadeau, Melanie R. Neeland, Sandra Andorf
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Measurement(s) expression profiling Technology Type(s) cytometry time of flight assay Sample Characteristic - Organism Homo sapiens Sample Characteristic - Location Australia
Externí odkaz:
https://doaj.org/article/597c792267ea43529751aaebfe2bdae3
Autor:
Abhinav Kaushik, Diane Dunham, Xiaorui Han, Evan Do, Sandra Andorf, Sheena Gupta, Andrea Fernandes, Laurie Elizabeth Kost, Sayantani B. Sindher, Wong Yu, Mindy Tsai, Robert Tibshirani, Scott D. Boyd, Manisha Desai, Holden T. Maecker, Stephen J. Galli, R. Sharon Chinthrajah, Rosemarie H. DeKruyff, Monali Manohar, Kari C. Nadeau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Oral immunotherapy (OIT) clinical trials have helped a subset of participants achieve sustained unresponsiveness (SU) to the cognate allergen. Here the authors analyse immune cells from participants from one peanut OIT trial and show that CD8+ T cell
Externí odkaz:
https://doaj.org/article/f3d3643e782c428e859a1f49273bc85c
Autor:
Zheng Yan, Holden T. Maecker, Petter Brodin, Unni C. Nygaard, Shu Chen Lyu, Mark M. Davis, Kari C. Nadeau, Sandra Andorf
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Broadly, much of variance in immune system phenotype has been linked to the influence of non-heritable factors rather than genetics. In particular, two non-heritable factors: aging and human cytolomegavirus (CMV) infection, have b
Externí odkaz:
https://doaj.org/article/1ee23ef593d442e79fbb86656f0f3b13
Autor:
Friederike Sonnet, Ellen Namork, Eva Stylianou, Ingvild Gaare-Olstad, Kanutte Huse, Sandra Andorf, Siri Mjaaland, Hubert Dirven, Unni Nygaard
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background The underlying cellular mechanisms causing adverse reactions to food are complex and still not fully understood. Therefore, in this study we aimed to identify functional and/or phenotypical immune cell signatures characteristic fo
Externí odkaz:
https://doaj.org/article/f170826615c34af19060c968ea4fb44a
Autor:
Melanie R. Neeland, Sandra Andorf, Monali Manohar, Diane Dunham, Shu-Chen Lyu, Thanh D. Dang, Rachel L. Peters, Kirsten P. Perrett, Mimi L. K. Tang, Richard Saffery, Jennifer J. Koplin, Kari C. Nadeau
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Food allergy is triggered by IgE, but some individuals are not allergic to peanuts despite making peanut-specific IgE, and are considered peanut-tolerant. Here, the authors identify differences in blood immune cell composition of peanut-allergic and
Externí odkaz:
https://doaj.org/article/966c4c38a8dd4e93886f0419ac4fec6a
Autor:
Sandra Andorf, Natasha Purington, Divya Kumar, Andrew Long, Katherine L. O'Laughlin, Scott Sicherer, Hugh Sampson, Antonella Cianferoni, Terri Brown Whitehorn, Daniel Petroni, Melanie Makhija, Rachel G. Robison, Michelle Lierl, Stephanie Logsdon, Manisha Desai, Stephen J. Galli, Efren Rael, Amal Assa'ad, Sharon Chinthrajah, Jacqueline Pongracic, Jonathan M. Spergel, Jonathan Tam, Stephen Tilles, Julie Wang, Kari Nadeau
Publikováno v:
EClinicalMedicine, Vol 7, Iss , Pp 27-38 (2019)
Background: As there is limited data on the sustainability of desensitization of multifood-oral immunotherapy (multifood-OIT), we conducted a multisite multifood-OIT study to compare the efficacy of successful desensitization with sustained dosing vs
Externí odkaz:
https://doaj.org/article/ffa27113723a48f18cdd5cd88e3a67b4
Autor:
Sayantani Sindher, Andrew J. Long, Natasha Purington, Madeleine Chollet, Sara Slatkin, Sandra Andorf, Dana Tupa, Divya Kumar, Margaret A. Woch, Katherine L. O’Laughlin, Amal Assaad, Jacqueline Pongracic, Jonathan M. Spergel, Jonathan Tam, Stephen Tilles, Julie Wang, Stephen J. Galli, Kari C. Nadeau, R. Sharon Chinthrajah
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/b372920fde1d49bfae50830d2a809da0
Autor:
Sandra Andorf, Monali Manohar, Tina Dominguez, Whitney Block, Dana Tupa, Rohun A. Kshirsagar, Vanitha Sampath, R. Sharon Chinthrajah, Kari C. Nadeau
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 13, Iss 1, Pp 1-8 (2017)
Abstract Background A number of clinical studies focused on treating a single food allergy through oral immunotherapy (OIT) with adjunctive omalizumab treatment have been published. We previously demonstrated safety and tolerability of a rapid OIT pr
Externí odkaz:
https://doaj.org/article/e95645cc65c64df9ad85144ae8dd5e2a
Autor:
Sandra Andorf, Monali Manohar, Tina Dominguez, Whitney Block, Dana Tupa, Rohun A. Kshirsagar, Vanitha Sampath, R. Sharon Chinthrajah, Kari C. Nadeau
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 13, Iss 1, Pp 1-10 (2017)
Abstract Background Clinical trials using oral immunotherapy (OIT) for the treatment of food allergies have shown promising results. We previously demonstrated the feasibility of desensitization for up to 5 food allergens simultaneously through OIT.
Externí odkaz:
https://doaj.org/article/0c8e2538d89f4e24b36d701153b5d287