Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sandra, Turcotte"'
Autor:
Mathieu Johnson, Sarah Nowlan, Gülsüm Sahin, David A. Barnett, Andrew P. Joy, Mohamed Touaibia, Miroslava Cuperlovic-Culf, Daina Zofija Avizonis, Sandra Turcotte
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Kidney cancer is one of the top ten cancer diagnosed worldwide and its incidence has increased the last 20 years. Clear Cell Renal Cell Carcinoma (ccRCC) are characterized by mutations that inactivate the von Hippel-Lindau (VHL) tumor suppressor gene
Externí odkaz:
https://doaj.org/article/5f3d652ddd3a49e68bd3850cf9d62e57
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
For a long time, lysosomes were considered as mere waste bags for cellular constituents. Thankfully, studies carried out in the past 15 years were brimming with elegant and crucial breakthroughs in lysosome research, uncovering their complex roles as
Externí odkaz:
https://doaj.org/article/988e36504bac4d23b49574ab08014008
Autor:
Patric Page, Sandra Turcotte, Mykella Martin, Patrick Richard, Tamiko Nishimura, Yasser Riazalhosseini
Publikováno v:
Cancer Research. 83:3787-3787
Background: Clear Cell Renal Cell Carcinoma (ccRCC) constitutes more than 75% of kidney cancer diagnostics. Inactivation of the tumor suppressor gene termed von Hippel-Lindau (VHL) is considered the major truncal event and occurs in more than 85% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb83d93b338fcb5b2f29bdc12259233
https://doi.org/10.1158/1538-7445.am2023-3787
https://doi.org/10.1158/1538-7445.am2023-3787
Autor:
Jolène Cormier, Sandra Turcotte
Publikováno v:
Cancer Research. 83:3617-3617
Introduction. Clear cell renal cell carcinoma (ccRCC) is the most frequent type of kidney cancer. These highly vascularized tumors are characterized by mutations that inactivate the von Hippel-Lindau (VHL) tumor suppressor gene. About 30 % of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16dddba8a3a3a0c52919e572318b024c
https://doi.org/10.1158/1538-7445.am2023-3617
https://doi.org/10.1158/1538-7445.am2023-3617
Autor:
Nadia Bouhamdani, Sandra Turcotte
Publikováno v:
Cancer Research. 83:3956-3956
Background. Clear cell renal cell carcinoma (ccRCC) is the most frequent type of cancer in the kidney. These tumors are highly vascular and correlate with poor prognosis. Biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0296f7424afb34290d4a4527b25d8a4
https://doi.org/10.1158/1538-7445.am2023-3956
https://doi.org/10.1158/1538-7445.am2023-3956
Autor:
Mathieu Johnson, Sandra Turcotte
Publikováno v:
Cancer Research. 83:2599-2599
The SETD2 gene encodes a histone methyltransferase responsible for the trimethylation of histone 3 on lysine 36 (H3K36me3). While this canonic function plays a role in the regulation of cellular processes such as transcription, alternative splicing,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c060666d32b1d941d13558fdb11c434c
https://doi.org/10.1158/1538-7445.am2023-2599
https://doi.org/10.1158/1538-7445.am2023-2599
Autor:
Mathieu Johnson, Sarah Nowlan, Gülsüm Sahin, David A. Barnett, Andrew P. Joy, Mohamed Touaibia, Miroslava Cuperlovic-Culf, Daina Zofija Avizonis, Sandra Turcotte
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Kidney cancer is one of the top ten cancer diagnosed worldwide and its incidence has increased the last 20 years. Clear Cell Renal Cell Carcinoma (ccRCC) are characterized by mutations that inactivate the von Hippel-Lindau (VHL) tumor suppressor gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a324cf0afd3e6ab6ae2e2d897199c46
https://pubmed.ncbi.nlm.nih.gov/35223522
https://pubmed.ncbi.nlm.nih.gov/35223522
Autor:
Ayyoub Selka, Sandra Turcotte, Pierre J. Lyons, Alison Chiasson, Marc E. Surette, Mohamed Touaibia, Marc Cormier, Sonia Dastous, Jérémie A. Doiron
Publikováno v:
European Journal of Medicinal Chemistry. 179:347-357
The inhibition of 5-lipoxygenase (5-LO), the key enzyme for the biosynthesis of leukotrienes (LTs), has generated increasing enthusiasm as anti-inflammatory and antitumor strategies in recent years. Based on our previous studies, we synthesized a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e69fa57464ad9a3bc6960bd765a71a
https://doi.org/10.1016/j.ejmech.2019.06.060
https://doi.org/10.1016/j.ejmech.2019.06.060
Publikováno v:
Carcinogenesis
The inactivation of the tumor suppressor gene, von Hippel-Lindau (VHL), has been identified as the earliest event in renal cell carcinoma (RCC) development. The loss of heterogeneity by chromosome 3p deletion followed by inactivating mutations on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b806ea791f6aee99264c272386c3f8c
https://doi.org/10.1093/carcin/bgz161
https://doi.org/10.1093/carcin/bgz161
Publikováno v:
American Journal of Physiology-Cell Physiology. 316:C605-C620
Autophagy is a highly conserved, homeostatic process by which cytosolic components reach lysosomes for degradation. The roles played by different autophagic processes in cancer are complex and remain cancer type and stage dependent. Renal cell carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42180cbf226acd83c3867b320c7c2dfb
https://doi.org/10.1152/ajpcell.00483.2018
https://doi.org/10.1152/ajpcell.00483.2018