Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sandra, Miksche"'
Autor:
Sandra Miksche, Nandor Ziebart, Yelena Mostinski, Judith de Schryver, Sylvia Oestreich, Christoph Rademacher, Yuliya Kolomeets, Martin Neuenschwander, Walter Birchmeier, Carola Seyffarth, Silke Radetzki, María P. López-Alberca, Guus J.J.E. Heynen, Jens Peter von Kries, Marc Nazaré, Elena Shanina, Yvette Roske, Jerome Paul, David Schaller, Andrea Volkamer, Udo Heinemann
Publikováno v:
Journal of Medicinal Chemistry. 63:14780-14804
The tyrosine phosphatase SHP2 controls the activity of pivotal signaling pathways, including MAPK, JAK-STAT, and PI3K-Akt. Aberrant SHP2 activity leads to uncontrolled cell proliferation, tumorigenesis, and metastasis. SHP2 signaling was recently lin
Autor:
María P. López-Alberca, Rana Alsalim, Marc Nazaré, Sandra Miksche, Werngard Czechtizky, Peter Lindemann, Nis Halland
Publikováno v:
Organic Letters. 22:7393-7396
The development of a novel selective synthesis of 3-amino-2H-indazoles from readily available 2-halobenzonitriles is presented. The reaction proceeds through a domino reaction sequence, consisting of a regioselective palladium-catalyzed coupling of m
Autor:
Rana, Alsalim, Peter, Lindemann, María Pascual, López-Alberca, Sandra, Miksche, Werngard, Czechtizky, Nis, Halland, Marc, Nazaré
Publikováno v:
Organic letters. 22(18)
The development of a novel selective synthesis of 3-amino-2