Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sandra, Kaminski"'
Autor:
Frederique Deshayes, Magali Fradet, Sandra Kaminski, Mireille Viguier, Jean-Pol Frippiat, Stephanie Ghislin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract EZH2 plays an essential role at the β-selection checkpoint of T lymphopoiesis by regulating histone H3 lysine 27 trimethylation (H3K27me3) via its canonical mode of action. Increasing data suggest that EZH2 could also regulate other cellula
Externí odkaz:
https://doaj.org/article/3c278066f76d49198367ef3cae2a915e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1720 (2023)
During spaceflights, astronauts face different forms of stress (e.g., socio-environmental and gravity stresses) that impact physiological functions and particularly the immune system. In this context, little is known about the effect of such stress o
Externí odkaz:
https://doaj.org/article/c55a62ea4c4a45aa8def7aedb9d417cd
Autor:
Ameziane Herzine, Ghita Sekkat, Sandra Kaminski, Gaetano Calcagno, Sandrine Boschi-Muller, Hela Safi, Catherine Corbier, Sophie Siest, Thomas Claudepierre, Frances T. Yen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8630 (2022)
Astroglia play an important role, providing de novo synthesized cholesterol to neurons in the form of ApoE-lipidated particles; disruption of this process can increase the risk of Alzheimer’s disease. We recently reported that glia-specific suppres
Externí odkaz:
https://doaj.org/article/7c54d77a3c254e5a977bd4ca97beeaf0
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7133 (2022)
Gravity changes are major stressors encountered during spaceflight that affect the immune system. We previously evidenced that hypergravity exposure during gestation affects the TCRβ repertoire of newborn pups. To identify the mechanisms underlying
Externí odkaz:
https://doaj.org/article/0f2e3f9c2cd0428494990006f4a6f016
Autor:
Aseel El Hajj, Ameziane Herzine, Gaetano Calcagno, Frédéric Désor, Fathia Djelti, Vincent Bombail, Isabelle Denis, Thierry Oster, Catherine Malaplate, Maxime Vigier, Sandra Kaminski, Lynn Pauron, Catherine Corbier, Frances T. Yen, Marie-Claire Lanhers, Thomas Claudepierre
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2049 (2022)
Perturbations of cholesterol metabolism have been linked to neurodegenerative diseases. Glia–neuron crosstalk is essential to achieve a tight regulation of brain cholesterol trafficking. Adequate cholesterol supply from glia via apolipoprotein E-co
Externí odkaz:
https://doaj.org/article/31531eb2ba6348b0816b5de0ef99a15e
Autor:
Natascha Hermann-Kleiter, Victoria Klepsch, Stephanie Wallner, Kerstin Siegmund, Sebastian Klepsch, Selma Tuzlak, Andreas Villunger, Sandra Kaminski, Christa Pfeifhofer-Obermair, Thomas Gruber, Dominik Wolf, Gottfried Baier
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 2072-2085 (2015)
Nuclear receptor subfamily 2, group F, member 6 (NR2F6) is an orphan member of the nuclear receptor superfamily. Here, we show that genetic ablation of Nr2f6 significantly improves survival in the murine transgenic TRAMP prostate cancer model. Furthe
Externí odkaz:
https://doaj.org/article/b95c927e50b446369adbcc97e8ec5495
Autor:
Nathan Guéguinou, Jérémy Jeandel, Sandra Kaminski, Sarah Baatout, Stéphanie Ghislin, Jean-Pol Frippiat
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1579 (2019)
The complement system plays an important role in inflammation, innate and acquired immunity, as well as homeostasis. Despite these functions, the effects of spaceflight conditions on the complement system have not yet been intensively studied. Conseq
Externí odkaz:
https://doaj.org/article/adb5c905db474a0b9204fd2821bb91ed
Autor:
Nikolaus Thuille, Katarzyna Wachowicz, Natascha Hermann-Kleiter, Sandra Kaminski, Friedrich Fresser, Christina Lutz-Nicoladoni, Michael Leitges, Margot Thome, Ramin Massoumi, Gottfried Baier
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53709 (2013)
In T cells PKCθ mediates the activation of critical signals downstream of TCR/CD28 stimulation. We investigated the molecular mechanisms by which PKCθ regulates NFκB transactivation by examining PKCθ/β single and double knockout mice and observe
Externí odkaz:
https://doaj.org/article/b1dfabdaa5b8404d82f6bee9d2a78395
Autor:
Laurence Lanfumey, Sandra Kaminski, Jean-Pol Frippiat, Charles Cohen-Salmon, Anne Vanet, Stéphanie Ghislin, Coralie Fonte
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2019, 33 (1), pp.896-908. ⟨10.1096/fj.201800969R⟩
FASEB Journal, 2019, 33 (1), pp.896-908. ⟨10.1096/fj.201800969R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2019, 33 (1), pp.896-908. ⟨10.1096/fj.201800969R⟩
FASEB Journal, 2019, 33 (1), pp.896-908. ⟨10.1096/fj.201800969R⟩
Spaceflights are known to affect the immune system. In a previous study, we demonstrated that hypergravity exposure during murine development modified 85% of the T-cell receptor (TCR)-β repertoire. In this study, we investigated whether socioenviron
Autor:
Julie Bonnefoy, Coralie Fonte, Stéphanie Ghislin, Gaetano Calcagno, Jean-Pol Frippiat, Jeremy Jeandel, Sandra Kaminski
Publikováno v:
Beyond LEO-Human Health Issues for Deep Space Exploration [Working Title]
Beyond LEO-Human Health Issues for Deep Space Exploration [Working Title], IntechOpen, 2019, ⟨10.5772/intechopen.88880⟩
Beyond LEO-Human Health Issues for Deep Space Exploration [Working Title], IntechOpen, 2019, ⟨10.5772/intechopen.88880⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e30929545a7b39bbc58713cb8668041
http://www.intechopen.com/articles/show/title/spaceflight-associated-immune-system-modifications
http://www.intechopen.com/articles/show/title/spaceflight-associated-immune-system-modifications