Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Sandra, Frank"'
Autor:
Agnieszka K. Czopik, Eóin N. McNamee, Victoria Vaughn, Xiangsheng Huang, In Hyuk Bang, Trent Clark, Yanyu Wang, Wei Ruan, Tom Nguyen, Joanne C. Masterson, Eunyoung Tak, Sandra Frank, Colm B. Collins, Howard Li, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Mark E. Gerich, Glenn T. Furuta, Xiaoyi Yuan, Anil K. Sood, Edwin F. de Zoeten, Holger K. Eltzschig
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Metabolic imbalance leading to inflammatory hypoxia and stabilization of hypoxia-inducible transcription factors (HIFs) is a hallmark of inflammatory bowel diseases. We hypothesize that HIF could be stabilized in CD4+ T cells during intestin
Externí odkaz:
https://doaj.org/article/a669e42b23f44430a2592da34005a047
Autor:
Helen Graf, Caroline Gräfe, Mathias Bruegel, Michael Zoller, Nils Maciuga, Sandra Frank, Lorenz Weidhase, Michael Paal, Christina Scharf
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Rhabdomyolysis is a serious condition that can lead to acute kidney injury with the need of renal replacement therapy (RRT). The cytokine adsorber Cytosorb® (CS) can be used for extracorporeal myoglobin elimination in patients wi
Externí odkaz:
https://doaj.org/article/067e3c59423447df8373dfcd9799b469
Autor:
Antonia Greimel, Katharina Habler, Caroline Gräfe, Nils Maciuga, Clara Isabell Brozat, Michael Vogeser, Michael Zoller, Felix L. Happich, Uwe Liebchen, Sandra Frank, Michael Paal, Christina Scharf
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background The release of toxic bile acids (BAs) in the blood of critically ill patients with cholestatic liver dysfunction might lead to the damage of various organs. Their extracorporeal elimination using the cytokine adsorber Cytosorb® (
Externí odkaz:
https://doaj.org/article/81795b989bbf4ba3a0fc1bb44fb81816
Autor:
Stefan Kluge, Alexander Zarbock, Patrick Meybohm, Christian Putensen, Stefan Hagel, Mathias W Pletz, Michael Bauer, Christian Jung, Markus A Weigand, Thorsten Brenner, Markus Heim, Stefan Münster, Sven Bercker, Sandra Fiedler, Frank Bloos, Maria Deja, Christian Ertmer, Peter Rosenberger, Helene Häberle, Jochen Dutzmann, Charlotte Ling, Andreas Güldner, Johannes Ehler, Sebastian Weis, Nicole Brillinger, Sebastian Decker, Philipp Franken, Alexander Vogt, Tobias Lahmer, Silke Fortenbach, Stefan John, Marc M. Berger, Axel Nierhaus, Friedhelm Bach, Raphael Bruno, Michael Zoller, Sandra Frank, Sarah Müller, Markus Feußner, Heinrich V Groesdonk, Ulrich Frey, Jan-Martin Wischermann, Mareike Otto, Matthias Lindner, Jan Heyckendorf, Caterina Reuchsel, Bernd Reichmann
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Herpes simplex virus (HSV) is frequently detected in the respiratory tract of mechanically ventilated patients and is associated with a worse outcome. The aim of this study is to determine whether antiviral therapy in HSV-positive patien
Externí odkaz:
https://doaj.org/article/c84813873bba43d0993e3e14947b10fa
Autor:
Alessandro Ghiani, Nikolaus Kneidinger, Claus Neurohr, Sandra Frank, Ludwig Christian Hinske, Christian Schneider, Sebastian Michel, Michael Irlbeck
Publikováno v:
Transplant International, Vol 36 (2023)
Prolonged mechanical ventilation (PMV) after lung transplantation poses several risks, including higher tracheostomy rates and increased in-hospital mortality. Mechanical power (MP) of artificial ventilation unifies the ventilatory variables that det
Externí odkaz:
https://doaj.org/article/40d3d8659a2846b39100499b063eb706
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Autor:
Carolin E. M. Koll, Sina M. Hopff, Thierry Meurers, Chin Huang Lee, Mirjam Kohls, Christoph Stellbrink, Charlotte Thibeault, Lennart Reinke, Sarah Steinbrecher, Stefan Schreiber, Lazar Mitrov, Sandra Frank, Olga Miljukov, Johanna Erber, Johannes C. Hellmuth, Jens-Peter Reese, Fridolin Steinbeis, Thomas Bahmer, Marina Hagen, Patrick Meybohm, Stefan Hansch, István Vadász, Lilian Krist, Steffi Jiru-Hillmann, Fabian Prasser, Jörg Janne Vehreschild, NAPKON Study Group
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-15 (2022)
Abstract Anonymization has the potential to foster the sharing of medical data. State-of-the-art methods use mathematical models to modify data to reduce privacy risks. However, the degree of protection must be balanced against the impact on statisti
Externí odkaz:
https://doaj.org/article/28a3080393434801b72639368e05f863
Autor:
Josef Briegel, Patrick Möhnle, Didier Keh, Johanna M. Lindner, Anna C. Vetter, Holger Bogatsch, Dorothea Lange, Sandra Frank, Ludwig C. Hinske, Djillali Annane, Michael Vogeser, SepNet Critical Care Trials Group
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)
Abstract Rationale Steroid profiles in combination with a corticotropin stimulation test provide information about steroidogenesis and its functional reserves in critically ill patients. Objectives We investigated whether steroid profiles before and
Externí odkaz:
https://doaj.org/article/ec704e575f7f401088f955b755c3edee
Autor:
Benedikt Schmid, Peter Kranke, Rudolf Lucas, Patrick Meybohm, Bernhard Zwissler, Sandra Frank
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract Background In May 2018, the first patient was enrolled in the phase-IIb clinical trial “Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Edema in Patients with Moderate to
Externí odkaz:
https://doaj.org/article/1f335ac8c09c46f6ba28d06e74949bd2
Autor:
Benedikt Schmid, Markus Kredel, Roman Ullrich, Katharina Krenn, Rudolf Lucas, Klaus Markstaller, Bernhard Fischer, Peter Kranke, Patrick Meybohm, Bernhard Zwißler, Sandra Frank, and the Solnatide Collaborators Group
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Acute respiratory distress syndrome (ARDS) is a complex clinical diagnosis with various possible etiologies. One common feature, however, is pulmonary permeability edema, which leads to an increased alveolar diffusion pathway and,
Externí odkaz:
https://doaj.org/article/cece7d96eaf943f4a322fc14c020fbd2
Autor:
Chrysanthi Tsamadou, Daphne Engelhardt, Uwe Platzbecker, Elisa Sala, Thomas Valerius, Eva Wagner-Drouet, Gerald Wulf, Nicolaus Kröger, Niels Murawski, Hermann Einsele, Kerstin Schaefer-Eckart, Sebastian Freitag, Jochen Casper, Martin Kaufmann, Mareike Dürholt, Bernd Hertenstein, Stefan Klein, Mark Ringhoffer, Sandra Frank, Christine Neuchel, Hubert Schrezenmeier, Joannis Mytilineos, Daniel Fuerst
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The HLA-DRB3/4/5 loci are closely linked to the HLA-DRB1 gene. Mismatches in these loci occur with a frequency of about 8%–12% in otherwise 10/10 HLA-matched transplant pairs. There is preliminary evidence that these disparities may associate with
Externí odkaz:
https://doaj.org/article/c7c6f5e3b8cd4fed80361f3be4facecf