Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sandra, Doß"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3022-3038 (2024)
A hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive
Externí odkaz:
https://doaj.org/article/7509311fa3dc4a079d6b3fd790c1447b
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 4639-4657 (2022)
(1) Antibiotics are an important weapon in the fight against serious bacterial infections and are considered a common cause of drug-induced liver injury (DILI). The hepatotoxicity of many drugs, including antibiotics, is poorly analyzed in human in v
Externí odkaz:
https://doaj.org/article/11f933b7f16947f780e3993872a4f344
Autor:
Gerd Klinkmann, Thomas Wild, Benjamin Heskamp, Fanny Doss, Sandra Doss, Lubomir Arseniev, Krasimira Aleksandrova, Martin Sauer, Daniel A. Reuter, Steffen Mitzner, Jens Altrichter
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Immune cell dysfunction plays a central role in sepsis-associated immune paralysis. The transfusion of healthy donor immune cells, i.e., granulocyte concentrates (GC) potentially induces tissue damage via local effects of neutroph
Externí odkaz:
https://doaj.org/article/a681af4282f545db9060d4e594599319
Publikováno v:
PeerJ, Vol 8, p e8568 (2020)
Albumin is the most abundant plasma protein and functions as a transport molecule that continuously interacts with various cell types. Because of these properties, albumin has been exploited by the pharmaceutical industry to improve drug delivery int
Externí odkaz:
https://doaj.org/article/17802ea236394287a2ee51d36668a360
Autor:
Gerd Klinkmann, Thomas Wild, Benjamin Heskamp, Fanny Doss, Sandra Doss, Magdalena Milej, Lea‐Marie Thiele, Lilia Goudeva, Rainer Blasczyk, Daniel A. Reuter, Jens Altrichter, Steffen Mitzner
Publikováno v:
Artificial Organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ecfa899b3fc6b1c512aecfbcde1391f
https://doi.org/10.1111/aor.14507
https://doi.org/10.1111/aor.14507
Autor:
Martin Sauer, Cristof Haubner, Georg Richter, Johannes Ehler, Thomas Mencke, Steffen Mitzner, Stefan Margraf, Jens Altrichter, Sandra Doß, Gabriele Nöldge-Schomburg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Liver dysfunction (LD) and liver failure are associated with poor outcome in critically ill patients. In patients with severe sepsis or septic shock, LD occurred in nearly 19% of patients. An early diagnosis of LD at time of initial damage of the liv
Externí odkaz:
https://doaj.org/article/8d7c6d38c0ea4b0c8c5fceb87de8c2a7
Autor:
Magdalena Milej, Gerd Klinkmann, Lilia Goudeva, Steffen Mitzner, Stephanie Koch, Rainer Blasczyk, Jens Altrichter, Sandra Doss, Fanny Doss
Publikováno v:
Transfusion. 62:194-204
BACKGROUND Use of donor granulocyte concentrate (GC) has been limited due to its short storage time of 6-24 h, which is partially due to residual red blood cells (RBCs) and platelets and the resulting lactate production leading to an acidotic milieu.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a177322702dafa0ddfa9b6349defac53
https://doi.org/10.1111/trf.16732
https://doi.org/10.1111/trf.16732
Autor:
Martin, Sauer, Georg, Richter, Jens, Altrichter, Thomas, Wild, Fanny, Doß, Thomas, Mencke, Johannes, Ehler, Sandra, Doß, Stephanie, Koch, Anton, Schubert, Gabriele, Nöldge-Schomburg, Steffen R, Mitzner
Publikováno v:
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 22(4)
A granulocyte bioreactor for the extracorporeal treatment was developed to enhance the immune cell function in patients with severe sepsis. The influence of oxygenation on the used cells was tested in a prospective clinical study. Ten patients with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bd7986305b2df33545bcd34a7b2c823
https://pubmed.ncbi.nlm.nih.gov/29418067
https://pubmed.ncbi.nlm.nih.gov/29418067
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2017 (2017)
BioMed Research International, Vol 2017 (2017)
Purpose. Drug-induced liver injury (DILI) is the most common cause of liver injury and a serious clinical problem; antimycotics are involved in approximately 3% of all DILI cases. The hepatotoxicity of many drugs, including the antimycotics, is poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58932781f859db1505d98800b3fd6111
Autor:
Georg Richter, Steffen Mitzner, Martin Sauer, Stephanie Koch, Annette Pertschy, Thomas Mencke, Maren Thomsen, Cristof Haubner, Jörg Henschel, Johannes Ehler, Thomas Wild, Gabriele Nöldge-Schomburg, Fanny Doß, Sandra Doß, Jens Altrichter
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2016 (2016)
BioMed Research International, Vol 2016 (2016)
Purpose.Granulocyte transfusions have been used to treat immune cell dysfunction in sepsis. A granulocyte bioreactor for the extracorporeal treatment of sepsis was tested in a prospective clinical study focusing on the dosage of norepinephrine in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13720503dae4ceaacd18a25b90225a27
https://pubmed.ncbi.nlm.nih.gov/27433475
https://pubmed.ncbi.nlm.nih.gov/27433475