Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sandor Szalma"'
Autor:
Hossein J. Sadaei, Aldo Cordova-Palomera, Jonghun Lee, Jaya Padmanabhan, Shang-Fu Chen, Nathan E. Wineinger, Raquel Dias, Daria Prilutsky, Sandor Szalma, Ali Torkamani
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Parkinson’s disease (PD) treatments modify disease symptoms but have not been shown to slow progression, characterized by gradual and varied motor and non-motor changes overtime. Variation in PD progression hampers clinical research, resul
Externí odkaz:
https://doaj.org/article/b53df21fcc3248ddb53ea381362d5008
Autor:
Aldo Córdova-Palomera, Csaba Siffel, Chris DeBoever, Emily Wong, Dorothée Diogo, Sandor Szalma
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285991 (2023)
As findings on the epidemiological and genetic risk factors for coronavirus disease-19 (COVID-19) continue to accrue, their joint power and significance for prospective clinical applications remains virtually unexplored. Severity of symptoms in indiv
Externí odkaz:
https://doaj.org/article/663871508a21485f87cbeab03a515768
Autor:
Liam Mahedy, Emma L. Anderson, Kate Tilling, Zak A. Thornton, Andrew R. Elmore, Sándor Szalma, Arthur Simen, Meredith Culp, Stephen Zicha, Brian T. Harel, George Davey Smith, Erin N. Smith, Lavinia Paternoster
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cognitive decline is a major health concern and identification of genes that may serve as drug targets to slow decline is important to adequately support an aging population. Whilst genetic studies of cross-sectional cognition have been carr
Externí odkaz:
https://doaj.org/article/7c74e97413254aebba9b6708c2e881d5
Autor:
Joseph D, Szustakowski, Suganthi, Balasubramanian, Erika, Kvikstad, Shareef, Khalid, Paola G, Bronson, Ariella, Sasson, Emily, Wong, Daren, Liu, J, Wade Davis, Carolina, Haefliger, A, Katrina Loomis, Rajesh, Mikkilineni, Hyun Ji, Noh, Samir, Wadhawan, Xiaodong, Bai, Alicia, Hawes, Olga, Krasheninina, Ricardo, Ulloa, Alex E, Lopez, Erin N, Smith, Jeffrey F, Waring, Christopher D, Whelan, Ellen A, Tsai, John D, Overton, William J, Salerno, Howard, Jacob, Sandor, Szalma, Heiko, Runz, Gregory, Hinkle, Paul, Nioi, Slavé, Petrovski, Melissa R, Miller, Aris, Baras, Lyndon J, Mitnaul, Jeffrey G, Reid, Zhan, Ye
Publikováno v:
Nature genetics. 53(7)
The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private-public partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that will complete the sequencing of exomes for all ~500,000 UKB participants. Here, we describe t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c26601afe79e40887910a1cec958420
https://pubmed.ncbi.nlm.nih.gov/34267364
https://pubmed.ncbi.nlm.nih.gov/34267364
Autor:
Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu, Jonasel Roque, Victoria P. Cepeda-Espinoza, Kazutoyo Osoegawa, Chris Hughes, Shirley C. Sutton, Nathan Youlton, Ruchi Joshi, David Amar, Yosuke Tanigawa, Douglas Russo, Justin Wong, Jessie T. Lauzon, Jacob Edelson, Daniel Mas Montserrat, Yongchan Kwon, Simone Rubinacci, Olivier Delaneau, Lorenzo Cappello, Jaehee Kim, Massa J. Shoura, Archana N. Raja, Nathaniel Watson, Nathan Hammond, Elizabeth Spiteri, Kalyan C. Mallempati, Gonzalo Montero-Martín, Jeffrey Christle, Jennifer Kim, Anna Kirillova, Kinya Seo, Yong Huang, Chunli Zhao, Sonia Moreno-Grau, Steven G. Hershman, Karen P. Dalton, Jimmy Zhen, Jack Kamm, Karan D. Bhatt, Alina Isakova, Maurizio Morri, Thanmayi Ranganath, Catherine A. Blish, Angela J. Rogers, Kari Nadeau, Samuel Yang, Andra Blomkalns, Ruth O’Hara, Norma F. Neff, Christopher DeBoever, Sándor Szalma, Matthew T. Wheeler, Christian M. Gates, Kyle Farh, Gary P. Schroth, Phil Febbo, Francis deSouza, Omar E. Cornejo, Marcelo Fernandez-Vina, Amy Kistler, Julia A. Palacios, Benjamin A. Pinsky, Carlos D. Bustamante, Manuel A. Rivas, Euan A. Ashley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using adm
Externí odkaz:
https://doaj.org/article/10002eca5587461185e42393a7dc16a5
Autor:
Oleg Stroganov, Alena Fedarovich, Emily Wong, Yulia Skovpen, Elena Pakhomova, Ivan Grishagin, Dzmitry Fedarovich, Tania Khasanova, David Merberg, Sándor Szalma, Julie Bryant
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0275816 (2022)
ObjectiveThe UK Biobank provides a rich collection of longitudinal clinical data coming from different healthcare providers and sources in England, Wales, and Scotland. Although extremely valuable and available to a wide research community, the heter
Externí odkaz:
https://doaj.org/article/81d32a6c6ca347f9846eb43b96147192
Autor:
Harald Schwalbe, Albert Eschenmoser, Gerhard Quinkert, Christian Richter, Sandor Szalma, Jochen Wermuth
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ada1fa2b69f198e56109b9896f56c8af
https://doi.org/10.1002/chin.200037226
https://doi.org/10.1002/chin.200037226
Autor:
Zoltán Oláh, Katalin Jósvay, László Pecze, Tamás Letoha, Norbert Babai, Dénes Budai, Ferenc Otvös, Sándor Szalma, Csaba Vizler
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e545 (2007)
Ca(2+)-loaded calmodulin normally inhibits multiple Ca(2+)-channels upon dangerous elevation of intracellular Ca(2+) and protects cells from Ca(2+)-cytotoxicity, so blocking of calmodulin should theoretically lead to uncontrolled elevation of intrace
Externí odkaz:
https://doaj.org/article/f77ba262583840ebbceb6a0d8cd0e666