Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sandor Benyhe"'
Autor:
Lorenza Marinaccio, Gokhan Zengin, Stefano Pieretti, Paola Minosi, Edina Szucs, Sandor Benyhe, Ettore Novellino, Domiziana Masci, Azzurra Stefanucci, Adriano Mollica
Publikováno v:
Food Chemistry: X, Vol 18, Iss , Pp 100640- (2023)
Rubiscolin-6 (amino acid sequence: YPLDLF) is a selective δ-opioid receptor peptide isolated from spinach Rubisco. Its synthetic analogue, peptide YPMDIV is the most potent described so far for its increased opioid activity, thus in this work it was
Externí odkaz:
https://doaj.org/article/8ae8bcac785b43ffa3acc6337d66acbf
Autor:
Karolina Frączek, Mattia Ferraiolo, Emmanuel Hermans, Magdalena Bujalska-Zadrozny, Kaja Kasarello, Anna Erdei, Kamila Kulik, Agnieszka Kowalczyk, Piotr Wojciechowski, Dorota Sulejczak, Piotr Sosnowski, Sebastian Granica, Sandor Benyhe, Katarzyna Kaczynska, Lukasz Nagraba, Artur Stolarczyk, Agnieszka Cudnoch-Jedrzejewska, Patrycja Kleczkowska
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1440-1452 (2020)
The behavioral responses exerted by spinal administration of the opioid-neurotensin hybrid peptide, PK23, were studied in adult male rats. The antinociceptive effect upon exposure to a thermal stimulus, as well as tolerance development, was assessed
Externí odkaz:
https://doaj.org/article/0b4c36e5be95411abe20ee43c316d799
Autor:
Adriano Mollica, Sveva Pelliccia, Valeria Famiglini, Azzurra Stefanucci, Giorgia Macedonio, Annalisa Chiavaroli, Giustino Orlando, Luigi Brunetti, Claudio Ferrante, Stefano Pieretti, Ettore Novellino, Sandor Benyhe, Ferenc Zador, Anna Erdei, Edina Szucs, Reza Samavati, Szabolcs Dvorácskó, Csaba Tomboly, Rino Ragno, Alexandros Patsilinakos, Romano Silvestri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 444-451 (2017)
Cannabinoid (CB) and opioid systems are both involved in analgesia, food intake, mood and behavior. Due to the co-localization of µ-opioid (MOR) and CB1 receptors in various regions of the central nervous system (CNS) and their ability to form heter
Externí odkaz:
https://doaj.org/article/150af71f751c4e86a5d678b1b514b7ea
Autor:
Giulio Poli, Marilisa Pia Dimmito, Adriano Mollica, Gokhan Zengin, Sandor Benyhe, Ferenc Zador, Azzurra Stefanucci
Publikováno v:
Molecules, Vol 24, Iss 21, p 3872 (2019)
Morphine, oxycodone, fentanyl, and other µ-opioid receptors (MOR) agonists have been used for decades in antinociceptive therapies. However, these drugs are associated with numerous side effects, such as euphoria, addiction, respiratory depression,
Externí odkaz:
https://doaj.org/article/feafdefcfb6f4c4bae3239398da7b8ca
Autor:
Luisa Rocha, Sandra Orozco-Suarez, Mario Alonso-Vanegas, Juana Villeda-Hernandez, Andres Gaona, Eszter Páldy, Sandor Benyhe, Anna Borsodi
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 3, Pp 466-473 (2009)
There is no information concerning signal transduction mechanisms downstream of the opioid/nociceptin receptors in the human epileptic brain. The aim of this work was to evaluate the level of G-proteins activation mediated by DAMGO (a mu receptor sel
Externí odkaz:
https://doaj.org/article/4cb92e14fc114a23984909ab85b0c1c2
Autor:
Azzurra Stefanucci, Alice Della Valle, Giuseppe Scioli, Lorenza Marinaccio, Stefano Pieretti, Paola Minosi, Edina Szucs, Sandor Benyhe, Domiziana Masci, Parthasaradhireddy Tanguturi, Kerry Chou, Deborah Barlow, Karen Houseknecht, John M. Streicher, Adriano Mollica
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1707-1714
Autor:
Anna K. Laskowska, Mateusz Szudzik, Aneta Ścieżyńska, Michał Komorowski, Edina Szűcs, Dávid Gombos, Bartłomiej Bączek, Jowita Lipka-Miciuk, Sandor Benyhe, Patrycja Kleczkowska
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5535
Despite the progress in early diagnostic and available treatments, pancreatic cancer remains one of the deadliest cancers. Therefore, there is an urgent need for novel anticancer agents with a good safety profile, particularly in terms of possible si
Autor:
Azzurra, Stefanucci, Alice, Della Valle, Giuseppe, Scioli, Lorenza, Marinaccio, Stefano, Pieretti, Paola, Minosi, Edina, Szucs, Sandor, Benyhe, Domiziana, Masci, Parthasaradhireddy, Tanguturi, Kerry, Chou, Deborah, Barlow, Karen, Houseknecht, John M, Streicher, Adriano, Mollica
Publikováno v:
ACS medicinal chemistry letters. 13(11)
Peripherally active tetrapeptides as selective κ opioid receptor (KOR) agonists have been prepared in good overall yields and high purity following solid-phase peptide synthesis via Fmoc protection strategy. Structural modifications at the first and
Autor:
Ferenc Ötvös, Edina Szűcs, Ákos Urai, István Köteles, Pál T. Szabó, Zsuzsanna Katalin Varga, Dávid Gombos, Sándor Hosztafi, Sándor Benyhe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Opiate alkaloids and their synthetic derivatives are still widely used in pain management, drug addiction, and abuse. To avoid serious side effects, compounds with properly designed pharmacological profiles at the opioid receptor subtypes ar
Externí odkaz:
https://doaj.org/article/b5b57eb3746046f899b96dbae84ce431
Autor:
David Á. Karádi, Anna Rita Galambos, Péter P. Lakatos, Joost Apenberg, Sarah K. Abbood, Mihály Balogh, Kornél Király, Pál Riba, Nariman Essmat, Edina Szűcs, Sándor Benyhe, Zoltán V. Varga, Éva Szökő, Tamás Tábi, Mahmoud Al-Khrasani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7970 (2023)
Despite the large arsenal of analgesic medications, neuropathic pain (NP) management is not solved yet. Angiotensin II receptor type 1 (AT1) has been identified as a potential target in NP therapy. Here, we investigate the antiallodynic effect of AT1
Externí odkaz:
https://doaj.org/article/f55ea3f921e045958b4c844b98212bbd