Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sandor, Györke"'
Autor:
Ingrid M. Bonilla, Stephen Baine, Anastasia Pokrass, Juan Ignacio Elio Mariángelo, Anuradha Kalyanasundaram, Vladimir Bogdanov, Louisa Mezache, Galina Sakuta, Casey M. Beard, Andriy Belevych, Svetlana Tikunova, Radmila Terentyeva, Dmitry Terentyev, Jonathan Davis, Rengasayee Veeraraghavan, Cynthia A. Carnes, Sandor Györke
Publikováno v:
Journal of Applied Physiology. 134:1287-1299
Store-operated Ca2+ entry (SOCE) has been implicated in pathological cardiac hypertrophy; however, its role in physiological hypertrophy is unknown. Here we report that SOCE is also essential for physiological cardiac hypertrophy and functional adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860459041ef77caeee38662e60940451
https://doi.org/10.1152/japplphysiol.00363.2022
https://doi.org/10.1152/japplphysiol.00363.2022
Autor:
Michael J. Wallace, Nipun Malhotra, Juan Ignacio Elio Mariángelo, Tyler L. Stevens, Lindsay J. Young, Steve Antwi-Boasiako, Danielle Abdallah, Sarah Sumie Takenaka, Omer Cavus, Nathaniel P. Murphy, Mei Han, Xianyao Xu, Matteo E. Mangoni, Thomas J. Hund, Jason D. Roberts, Sandor Györke, Peter J. Mohler, Mona El Refaey
Publikováno v:
Journal of Biological Chemistry. :104818
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489b1ae3695593e5291e7eab7412403b
https://doi.org/10.1016/j.jbc.2023.104818
https://doi.org/10.1016/j.jbc.2023.104818
Autor:
Gwendolen Lorch, Serge Viatchenko-Karpinski, Hsiang-Ting Ho, Wessel P. Dirksen, Ramiro E. Toribio, John Foley, Sandor Györke, Thomas J. Rosol
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 5, Pp 428-438 (2011)
The calcium-sensing receptor (CaR) is responsible for the regulation of extracellular calcium (Ca2+o) homeostasis. CaR activation has been shown to increase proliferation in several cancer cell lines; however, its presence or function has never been
Externí odkaz:
https://doaj.org/article/13d80f320c474a228fde315f88000ace
Autor:
Shanna, Hamilton, Radmila, Terentyeva, Fruzsina, Perger, Benjamín, Hernández Orengo, Benjamin, Martin, Matthew W, Gorr, Andriy E, Belevych, Richard T, Clements, Sandor, Györke, Dmitry, Terentyev
Publikováno v:
Am J Physiol Heart Circ Physiol
Cardiac dysfunction in heart failure (HF) and diabetic cardiomyopathy (DCM) is associated with aberrant intracellular Ca(2+) handling and impaired mitochondrial function accompanied with reduced mitochondrial calcium concentration (mito-[Ca(2+)]). Ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c02b4696d2c69a719c9623aad88804d
https://pubmed.ncbi.nlm.nih.gov/34415186
https://pubmed.ncbi.nlm.nih.gov/34415186
Publikováno v:
Biological Research, Vol 37, Iss 4, Pp 603-607 (2004)
Calsequestrin (CASQ2) is a high capacity Ca-binding protein expressed inside the sarcoplasmic reticulum (SR). Mutations in the cardiac calsequestrin gene (CASQ2) have been linked to arrhythmias and sudden death induced by exercise and emotional stres
Externí odkaz:
https://doaj.org/article/05496cb2c34b491b8a6e9a84d18c6b70
Autor:
Ingrid M Bonilla, Victor P Long, Pedro Vargas-Pinto, Patrick Wright, Andriy Belevych, Qing Lou, Kent Mowrey, Jae Yoo, Philip F Binkley, Vadim V Fedorov, Sandor Györke, Paulus M L Janssen, Ahmet Kilic, Peter J Mohler, Cynthia A Carnes
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108824 (2014)
The role of I(KCa) in cardiac repolarization remains controversial and varies across species. The relevance of the current as a therapeutic target is therefore undefined. We examined the cellular electrophysiologic effects of I(KCa) blockade in contr
Externí odkaz:
https://doaj.org/article/6a6220e6898943efbd5f6ac67f57f16c
Autor:
Andriy E Belevych, Sarah E Sansom, Radmila Terentyeva, Hsiang-Ting Ho, Yoshinori Nishijima, Mickey M Martin, Hitesh K Jindal, Jennifer A Rochira, Yukiko Kunitomo, Maha Abdellatif, Cynthia A Carnes, Terry S Elton, Sandor Györke, Dmitry Terentyev
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28324 (2011)
In heart failure (HF), arrhythmogenic spontaneous sarcoplasmic reticulum (SR) Ca(2+) release and afterdepolarizations in cardiac myocytes have been linked to abnormally high activity of ryanodine receptors (RyR2s) associated with enhanced phosphoryla
Externí odkaz:
https://doaj.org/article/82b72743a2f04eee91cbcfb491c230a0
Autor:
Christopher N, Johnson, Rekha, Pattanayek, Franck, Potet, Robyn T, Rebbeck, Daniel J, Blackwell, Roman, Nikolaienko, Vasco, Sequeira, Remy, Le Meur, Przemysław B, Radwański, Jonathan P, Davis, Aleksey V, Zima, Razvan L, Cornea, Steven M, Damo, Sandor, Györke, Alfred L, George, Björn C, Knollmann
Publikováno v:
Cell Calcium
Here we report the structure of the widely utilized calmodulin (CaM)-dependent protein kinase II (CaMKII) inhibitor KN93 bound to the Ca(2+)-sensing protein CaM. KN93 is widely believed to inhibit CaMKII by binding to the kinase. The CaM-KN93 interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d311458be0ae13ccb17a5c29535b117
https://pubmed.ncbi.nlm.nih.gov/31401388
https://pubmed.ncbi.nlm.nih.gov/31401388
Autor:
Hsiang-Ting Ho, Belevych, Andriy E., Liu, Bin, Bonilla, Ingrid M., Przemyslaw B Radwanski, Kubasov, Igor V., Valdivia, Hector H., Schober, Karsten, Carnes, Cynthia A., Sandor Györke
Although the effects and the underlying mechanism of sympathetic stimulation on cardiac Ca handling are relatively well established both in health and disease, the modes of action and mechanisms of parasympathetic modulation are poorly defined. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1db04c6b0a5f1aa06eb2fec2206fa01
Autor:
Radmila Terentyeva, Dmitry Terentyev, Inna Györke, Simon C. Williams, Serge Viatchenko-Karpinski, Zuzana Kubalova, Sandor Györke
Publikováno v:
The Journal of Physiology. 561:515-524
Waves of Ca2+-induced Ca2+ release occur in various cell types and are involved in the pathology of certain forms of cardiac arrhythmia. These arrhythmias include catecholaminergic polymorphic ventricular tachycardia (CPVT), certain cases of which ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4701e15507c5b8bc9635df20e541c58
https://doi.org/10.1113/jphysiol.2004.073940
https://doi.org/10.1113/jphysiol.2004.073940