Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sandipan Brahma"'
Autor:
Saurabh K. Bhardwaj, Solomon G. Hailu, Lola Olufemi, Sandipan Brahma, Soumyadipta Kundu, Swetansu K. Hota, Jim Persinger, Blaine Bartholomew
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Here the authors show that the preference of yeast chromatin remodeler ISW1a for dinucleosomes hinges on conformational changes that occur in the transition from binding mononucleosomes to dinucleosomes. These changes are critical for ISW1a organizin
Externí odkaz:
https://doaj.org/article/3925090b229e433189477ec58c630f47
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
INO80 chromatin remodeler plays important roles in transcription, DNA repair, recombination, and heterochromatin maintenance. Here the authors characterise the functional interplay between the actin-related proteins (Arps) in INO80, showing that Arp8
Externí odkaz:
https://doaj.org/article/e00fc131e6374772ad0cb36e70283b47
Autor:
Sandipan Brahma, Maheshi I. Udugama, Jongseong Kim, Arjan Hada, Saurabh K. Bhardwaj, Solomon G. Hailu, Tae-Hee Lee, Blaine Bartholomew
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Chromatin remodellers usually mobilize or disassemble nucleosomes by translocating along the nucleosomal DNA at the H3-H4 interface. Here, the authors provide evidence chromatin remodeller INO80 translocates along DNA at the H2A-H2B interface and dis
Externí odkaz:
https://doaj.org/article/efde14d4e3754f9bbcffa95733e77a87
Autor:
Payel Sen, Jie Luo, Arjan Hada, Solomon G. Hailu, Mekonnen Lemma Dechassa, Jim Persinger, Sandipan Brahma, Somnath Paul, Jeff Ranish, Blaine Bartholomew
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2135-2147 (2017)
Summary: The SWI/SNF chromatin remodeling complex is highly conserved from yeast to human, and aberrant SWI/SNF complexes contribute to human disease. The Snf5/SMARCB1/INI1 subunit of SWI/SNF is a tumor suppressor frequently lost in pediatric rhabdoi
Externí odkaz:
https://doaj.org/article/45e74331e16f4211a99bb29b8da26257
Autor:
Gavin Ha, Peter S. Nelson, Steven Henikoff, Eva Corey, R. Bruce Montgomery, Michael C. Haffner, Kami Ahmad, Matthew L. Freedman, Jacob E. Berchuck, Sylvan C. Baca, Atish D. Choudhury, Colm Morrissey, Michael T. Schweizer, Colin C. Pritchard, Heather M. McClure, Holly M. Nguyen, Talina A. Nunez, Jared M. Lucas, Ruth F. Dumpit, Arnab Bose, Ilsa M. Coleman, Lisa S. Ang, Derek H. Janssens, Michael P. Meers, Sandipan Brahma, Minjeong Ko, Jay F. Sarthy, Adam J. Kreitzman, Mohamed Adil, Brian Hanratty, Anna-Lisa Doebley, Robert D. Patton, Navonil De Sarkar
Feature-region combination AUCs and benchmarking Sheet 1: Log2 fold-change, p-value, and q-value between ARPC and NEPC lines for central mean coverage in all queried (338) TFs (two tailed Mann-Whitney U test, Benjamini-Hochberg adjusted). Sheet 2: 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131f41ff743e41934b8e4242f49253ae
https://doi.org/10.1158/2159-8290.22674256
https://doi.org/10.1158/2159-8290.22674256
Autor:
Gavin Ha, Peter S. Nelson, Steven Henikoff, Eva Corey, R. Bruce Montgomery, Michael C. Haffner, Kami Ahmad, Matthew L. Freedman, Jacob E. Berchuck, Sylvan C. Baca, Atish D. Choudhury, Colm Morrissey, Michael T. Schweizer, Colin C. Pritchard, Heather M. McClure, Holly M. Nguyen, Talina A. Nunez, Jared M. Lucas, Ruth F. Dumpit, Arnab Bose, Ilsa M. Coleman, Lisa S. Ang, Derek H. Janssens, Michael P. Meers, Sandipan Brahma, Minjeong Ko, Jay F. Sarthy, Adam J. Kreitzman, Mohamed Adil, Brian Hanratty, Anna-Lisa Doebley, Robert D. Patton, Navonil De Sarkar
Supplementary Figures S1-S18 and Supplementary Table legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a676746f9874d80588b96e87e41d0812
https://doi.org/10.1158/2159-8290.22674268.v1
https://doi.org/10.1158/2159-8290.22674268.v1
Autor:
Steven Henikoff, SANDIPAN BRAHMA
Chromatin accessibility is a hallmark of active transcription and requires ATP-dependent nucleosome remodeling by Brahma-Associated Factor (BAF). However, the mechanistic link between transcription, nucleosome remodeling, and chromatin accessibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678a9e4055d3287054e8116db6021580
https://doi.org/10.1101/2023.01.22.525083
https://doi.org/10.1101/2023.01.22.525083
Autor:
Navonil De Sarkar, Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman, Jay F. Sarthy, Minjeong Ko, Sandipan Brahma, Michael P. Meers, Derek H. Janssens, Lisa S. Ang, Ilsa M. Coleman, Arnab Bose, Ruth F. Dumpit, Jared M. Lucas, Talina A. Nunez, Holly M. Nguyen, Heather M. McClure, Colin C. Pritchard, Michael T. Schweizer, Colm Morrissey, Atish D. Choudhury, Sylvan C. Baca, Jacob E. Berchuck, Matthew L. Freedman, Kami Ahmad, Michael C. Haffner, R. Bruce Montgomery, Eva Corey, Steven Henikoff, Peter S. Nelson, Gavin Ha
Publikováno v:
Cancer discovery.
Advanced prostate cancers comprise distinct phenotypes, but tumor classification remains clinically challenging. Here, we harnessed circulating tumor DNA (ctDNA) to study tumor phenotypes by ascertaining nucleosome positioning patterns associated wit
Autor:
Sandipan, Brahma, Steven, Henikoff
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2477
Mapping the epigenome is key to describe the relationship between chromatin landscapes and the control of DNA-based cellular processes such as transcription. Cleavage under targets and release using nuclease (CUTRUN) is an in situ chromatin profiling
Autor:
Blaine Bartholomew, Swetansu K. Hota, Jim Persinger, Lola Olufemi, Saurabh K. Bhardwaj, Solomon G. Hailu, Soumyadipta Kundu, Sandipan Brahma
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Over the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize chromatin at the level of single nucleosomes rather than higher-order organization of more than one nucleosome. We show the yeast ISW1a remodeler has such highe