Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Sandip M Kanse"'
Autor:
Hannah J Harjen, Marit Hellum, Runa Rørtveit, Malin Oscarson, Kristin P Anfinsen, Elena R Moldal, Susanna Solbak, Sandip M Kanse, Carola E Henriksson
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263238 (2022)
BackgroundEnvenomation by the European adder, Vipera berus berus (Vbb), is a medical emergency. The overall in vivo haemostatic effects of pro- and anticoagulant components in Vbb venom, and the downstream effects of cellular injury and systemic infl
Externí odkaz:
https://doaj.org/article/5f6305502c2245d285495da74e10e1bf
Autor:
Bernd Uhl, Laura AMittmann, Julian Dominik, Roman Hennel, Bojan Smiljanov, Florian Haring, Johanna BSchaubächer, Constanze Braun, Lena Padovan, Robert Pick, Martin Canis, Christian Schulz, Matthias Mack, Ewgenija Gutjahr, Peter Sinn, Jörg Heil, Katja Steiger, Sandip M Kanse, Wilko Weichert, Markus Sperandio, Kirsten Lauber, Fritz Krombach, Christoph A Reichel
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp n/a-n/a (2021)
Abstract High intratumoral levels of urokinase‐type plasminogen activator (uPA)‐plasminogen activator inhibitor‐1 (PAI‐1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of this protei
Externí odkaz:
https://doaj.org/article/4c70973c2a744ff8b94cdcdb9b282bf8
Autor:
Christoph A Reichel, Maximilian E T Hessenauer, Kerstin Pflieger, Markus Rehberg, Sandip M Kanse, Stefan Zahler, Fritz Krombach, Alexander Berghaus, Sebastian Strieth
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116883 (2015)
Rapid fibrovascularization is a prerequisite for successful biomaterial engraftment. In addition to their well-known roles in fibrinolysis, urokinase-type plasminogen activator (uPA) and tissue plasminogen activator (tPA) or their inhibitor plasminog
Externí odkaz:
https://doaj.org/article/e481b81df87b4b4e82b831b0194ae9d9
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13706 (2022)
Factor-VII-activating protease (FSAP) is involved in the regulation of hemostasis and inflammation. Extracellular histones play a role in inflammation and the conversion of latent pro-FSAP into active FSAP. FSAP has been shown to regulate endothelial
Externí odkaz:
https://doaj.org/article/8d2161e049dd40da822a415ecedff954
Autor:
Mariana S. Parahuleva, Michael Worsch, Gerhild Euler, Maryana Choukeir, Amar Mardini, Behnoush Parviz, Sandip M. Kanse, Irene Portig, Evgeny Khayrutdinov, Bernhard Schieffer, Birgit Markus
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 17 (2020)
Background Factor VII activating protease (FSAP) is of interest as a marker for vascular inflammation and plaque destabilization. The aim of this study was to analyze the expression profile of FSAP in endarterectomy specimens that were taken from pat
Externí odkaz:
https://doaj.org/article/3dde9f7aa1a34b1b94e6ac7ca69d435e
Autor:
Omary Chillo, Eike Christian Kleinert, Thomas Lautz, Manuel Lasch, Judith-Irina Pagel, Yvonn Heun, Kerstin Troidl, Silvia Fischer, Amelia Caballero-Martinez, Annika Mauer, Angela R.M. Kurz, Gerald Assmann, Markus Rehberg, Sandip M. Kanse, Bernhard Nieswandt, Barbara Walzog, Christoph A. Reichel, Hanna Mannell, Klaus T. Preissner, Elisabeth Deindl
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2197-2207 (2016)
The body has the capacity to compensate for an occluded artery by creating a natural bypass upon increased fluid shear stress. How this mechanical force is translated into collateral artery growth (arteriogenesis) is unresolved. We show that extravas
Externí odkaz:
https://doaj.org/article/29290659cd284108ba015bffadecf23e
Publikováno v:
The FASEB Journal. 36
The outcome of ischemic stroke can be improved by further refinements of thrombolysis and reperfusion strategies. Factor VII activating protease (FSAP) is a circulating serine protease that could be important in this context. Its levels are raised in
Autor:
Philipp Markart, Peter A. Andreasen, Andreas Guenther, Klaus T. Preissner, Troels Wind, Rory E. Morty, Malgorzata Wygrecka, Sandip M. Kanse
Publikováno v:
The Journal of Biological Chemistry
Factor VII-activating protease (FSAP) is a novel plasma-derived serine protease structurally homologous to tissue-type and urokinase-type plasminogen activators. We demonstrate that plasminogen activator inhibitor-1 (PAI-1), the predominant inhibitor
Factor VII activating protease (FSAP) is a circulating serine protease, and individuals with the Marburg I (MI) single nucleotide polymorphism (SNP), which results in an inactive enzyme, have an increased risk of stroke. The outcome of ischemic strok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7caead7986af8a4fd13c6a936714ca5
https://doi.org/10.1101/2022.01.12.476006
https://doi.org/10.1101/2022.01.12.476006
Autor:
Sebastian Seidl, Nis Valentin Nielsen, Michael Escheid, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
Increased Factor VII activating protease (FSAP) activity has a protective effect in diverse disease conditions as inferred from studies in FSAP−/− mice and humans deficient in FSAP activity due to a single nucleotide polymorphism. The activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bab935607a25f3e39e2a20180ce336
https://doi.org/10.1101/2022.01.09.475526
https://doi.org/10.1101/2022.01.09.475526