Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sandip K. Rath"'
Autor:
Melanie S. Hulshoff, Isabel N. Schellinger, Xingbo Xu, Jolien Fledderus, Sandip K. Rath, Fang Cheng Wong, Sabine Maamari, Josephina Haunschild, Guido Krenning, Uwe Raaz, Elisabeth M. Zeisberg
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background The prevalence of diabetes mellitus has risen considerably and currently affects more than 422 million people worldwide. Cardiovascular diseases including myocardial infarction and heart failure represent the major cause of death
Externí odkaz:
https://doaj.org/article/05337be52fd4401f9524f4a2313004de
Autor:
Priya Kapoor-Vazirani, Sandip K. Rath, Xu Liu, Zhen Shu, Nicole E. Bowen, Yitong Chen, Ramona Haji-Seyed-Javadi, Waaqo Daddacha, Elizabeth V. Minten, Diana Danelia, Daniela Farchi, Duc M. Duong, Nicholas T. Seyfried, Xingming Deng, Eric A. Ortlund, Baek Kim, David S. Yu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
SAMHD1 has a dNTPase-independent resection function in genome maintenance. Here the authors show that SAMHD1 is deacetylated at conserved K354 by SIRT1 to facilitate direct binding with ssDNA to promote DNA end resection and homologous recombination.
Externí odkaz:
https://doaj.org/article/28cc02127faa4de9bf5e662150744115
Publikováno v:
Seminars in Nephrology. 38:629-636
Cardiovascular disease and heart failure are the primary cause of morbidity and mortality in patients with chronic kidney disease. Because impairment of kidney function correlates with heart failure and cardiac fibrosis, a kidney-heart axis is suspec