Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sandip Ashok Sonar"'
Publikováno v:
Journal of Leukocyte Biology. 112:1497-1507
Several subsets of CD8+ T cells are known to have a suppressive function in different tissues and diseases in mice and humans. Due to the lack of a consensus on the phenotype of regulatory CD8+ T cells and very low frequency in the body, its clinical
Transcription factors T-bet and RORψt play a crucial role in neuronal autoimmunity, and mice deficient in these two factors do not develop experimental autoimmune encephalomyelitis (EAE). The independent role of T-bet and RORψt in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a9372ab2df90a9470d2c9f077cca14c
https://doi.org/10.1101/2023.04.17.537133
https://doi.org/10.1101/2023.04.17.537133
Autor:
Sandip Ashok Sonar, Girdhari Lal
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Inducible nitric oxide synthase (iNOS) plays a critical role in the regulation of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Previous studies have shown that iNOS plays pathogenic as well as regulatory roles in MS an
Externí odkaz:
https://doaj.org/article/5384d56248d94542bc28e14a6b9e11ac
Autor:
Sandip Ashok Sonar, Girdhari Lal
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
CD4+ T cells play a central role in orchestrating protective immunity and autoimmunity. The activation and differentiation of myelin-reactive CD4+ T cells into effector (Th1 and Th17) and regulatory (Tregs) subsets at the peripheral tissues, and thei
Externí odkaz:
https://doaj.org/article/4404097a3f8340db825cb01b0cbd4d70
Autor:
Marcel R.M. van den Brink, Christopher P. Coplen, Jennifer L. Uhrlaub, Bonnie LaFleur, Sandip Ashok Sonar, Janko Nikolich-Zugich, Mladen Jergović, Gregory D. Sempowski, Jarrod A Dudakov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(17)
Secondary lymphoid organs (SLO; including the spleen and lymph nodes) are critical both for the maintenance of naïve T (TN) lymphocytes and for the initiation and coordination of immune responses. How they age, including the exact timing, extent, ph
Autor:
Manisha Pathak, Namrita Halder, Sandip Ashok Sonar, Priyanka Padghan, Shilpi, Girdhari Lal, Neeraja Kulkarni
Publikováno v:
European Journal of Immunology. 50:404-417
The chemokine receptor CCR9 and its only known ligand CCL25 play an important role in gut inflammation and autoimmune colitis. The function of CCR9-CCL25 in the migration of immune cells is well characterized. However, its role in the immune cell dif
Autor:
Sandip Ashok Sonar, Jarrod A Dudakov, Christine M. Bradshaw, Mladen Jergović, Christoper P. Coplen, Kristy O. Murray, Marion C. Lanteri, Janko Nikolich-Žugich, Marcel R.M. van den Brink, Jennifer L. Uhrlaub, Michael P. Busch
Older humans and animals often exhibit reduced immune responses to infection and vaccination, and this often directly correlates to the numbers and frequency of naïve T (Tn) cells. We found such a correlation between reduced numbers of blood CD8+ Tn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655b68cd696425e7fc24d8bd08a45139
https://doi.org/10.1101/2021.08.09.453882
https://doi.org/10.1101/2021.08.09.453882
Publikováno v:
Immunology & Cell Biology. 95:843-853
Transendothelial migration (TEM) of Th1 and Th17 cells across the blood-brain barrier (BBB) has a critical role in the development of experimental autoimmune encephalomyelitis (EAE). How cytokines produced by inflammatory Th1 and Th17 cells damage th
Autor:
Sandip Ashok Sonar, Girdhari Lal
Publikováno v:
Contemporary Clinical Neuroscience ISBN: 9783030195144
The neuroimmune diseases are caused by autoimmune demyelination, opportunistic and neurotrophic infections, paraneoplastic conditions, neurodegeneration, and neuropsychiatric disorders. These diseases are multifactorial, complex, and heterogeneous wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5789da51242de5a6532c7740c39182
https://doi.org/10.1007/978-3-030-19515-1_1
https://doi.org/10.1007/978-3-030-19515-1_1
Publikováno v:
Indian Journal of Inflammation Research. 1
The gut immune system is very complex and a single layer of the epithelial barrier along the gastrointestinal tract prevents the evasion of various extracellular commensal and pathogenic microorganisms in the gut mucosa. The inflammatory bowel diseas