Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sandii, Constable"'
Autor:
Julien Ferent, Sandii Constable, Eduardo D. Gigante, Patricia T. Yam, Laura E. Mariani, Emilie Legué, Karel F. Liem, Jr., Tamara Caspary, Frédéric Charron
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3356-3366.e3 (2019)
Summary: The small GTPase Arl13b is enriched in primary cilia and regulates Sonic hedgehog (Shh) signaling. During neural development, Shh controls patterning and proliferation through a canonical, transcription-dependent pathway that requires the pr
Externí odkaz:
https://doaj.org/article/9a2d657e0e474c2d9ac61327fe688811
Publikováno v:
Hedgehog Signaling ISBN: 9781071617007
The identity of ventral neural progenitors in the neural tube is largely dependent on Hedgehog (Hh) signaling. Variations in staining patterns are excellent indicators of aberrant Hh signaling. Here we describe the basic protocol to stain for progeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec50750cb960ca7d719b7ef29d6e29f
https://doi.org/10.1007/978-1-0716-1701-4_6
https://doi.org/10.1007/978-1-0716-1701-4_6
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2374
The identity of ventral neural progenitors in the neural tube is largely dependent on Hedgehog (Hh) signaling. Variations in staining patterns are excellent indicators of aberrant Hh signaling. Here we describe the basic protocol to stain for progeni
Autor:
Dagmar Wachten, Christy Catalano, Lei Xing, Garret D. Stuber, Tamara Caspary, E.S. Anton, Jeremy M. Simon, Janice Lee, Stephanie L. Gupton, Stéphane Schurmans, James M. Otis, Katherine H. Blackley, Sandii Constable, Amelia Lee, Sarah K. Suciu, Travis S. Ptacek, Jiami Guo
Publikováno v:
Developmental Cell
Dev Cell
Dev Cell
Summary Appropriate axonal growth and connectivity are essential for functional wiring of the brain. Joubert syndrome-related disorders (JSRD), a group of ciliopathies in which mutations disrupt primary cilia function, are characterized by axonal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddcf964c8b55e026c12dd07c70a62dd
https://hdl.handle.net/21.11116/0000-0006-41FA-721.11116/0000-0006-41FC-5
https://hdl.handle.net/21.11116/0000-0006-41FA-721.11116/0000-0006-41FC-5
Autor:
Saikat Mukhopadhyay, Sandii Constable
Publikováno v:
Dev Cell
The etiology of congenital heart defects (CHDs), amongst the most common human birth defects, is poorly understood because of its complex genetic architecture. Here we show that two genes implicated in CHDs, Megf8 and Mgrn1, interact genetically and
Publikováno v:
Development
Sonic hedgehog (Shh) signal transduction specifies ventral cell fates in the neural tube and is mediated by the Gli transcription factors that play both activator (GliA) and repressor (GliR) roles. Cilia are essential for Shh signal transduction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84e59636e2ef1f2826e12078c0164e1
https://doi.org/10.1101/721399
https://doi.org/10.1101/721399
O-linked β-N-acetylglucosamine (O-GlcNAc) is a single sugar modification found on many different classes of nuclear and cytoplasmic proteins. Addition of this modification, by the enzyme O-linked N-acetylglucosamine transferase (OGT), is dynamic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc85e276ed3d66c24726beccd01a9e4
https://europepmc.org/articles/PMC6410957/
https://europepmc.org/articles/PMC6410957/