Brain microglia in psychiatric disorders

Autor: Mondelli, Valeria, Vernon, Anthony C, Turkheimer, Federico, Dazzan, Paola, Pariante, Carmine M, Frost, JL, Schafer, DP, Banati, RB, Newcombe, J, Gunn, RN, al., et, Tang, Y, Le, W, Estes, ML, McAllister, AK, Ransohoff, RM, Davalos, D, Grutzendler, J, Yang, G, Peferoen, LA, Vogel, DY, Ummenthum, K, Norden, DM, Trojanowski, PJ, Villanueva, E, Navarro, E, Godbout, JP, Kreisel, T, Frank, MG, Licht, T, Wachholz, S, Eßlinger, M, Plümper, J, Manitz, MP, Juckel, G, Friebe, A, Trépanier, MO, Hopperton, KE, Mizrahi, R, Mechawar, N, Bazinet, RP, Torres-Platas, SG, Cruceanu, C, Chen, GG, Turecki, G, Steiner, J, Bielau, H, Brisch, R, Schnieder, TP, Trencevska, I, Rosoklija, G, Fillman, SG, Cloonan, N, Catts, VS, Rupprecht, R, Papadopoulos, V, Rammes, G, Qiu, ZK, Li, MS, He, JL, Hannestad, J, Gallezot, JD, Schafbauer, T, Israel, I, Ohsiek, A, Al-Momani, E, Mirzaei, N, Tang, SP, Ashworth, S, Gulyás, B, Makkai, B, Kása, P, Turkheimer, FE, Rizzo, G, Bloomfield, PS, Owen, DR, Yeo, AJ, DellaGioia, N, Setiawan, E, Wilson, AA, Su, L, Faluyi, YO, Hong, YT, Haarman, BC, Lek, RF Riemersma-Van der, Groot, JC de, Berckel, BN van, Bossong, MG, Boellaard, R, Doorduin, J, Vries, EF de, Willemsen, AT, Dierckx, RA, Klein, HC, Takano, A, Arakawa, R, Ito, H, Kenk, M, Selvanathan, T, Rao, N, Selvaraj, S, Veronese, M, Coughlin, JM, Wang, Y, Ambinder, EB, Doef, TF van der, Witte, LD de, Sutterland, AL, Hafizi, S, Tseng, HH, Holmes, SE, Hinz, R, Drake, RJ, Yaqub, M, Schuitemaker, A, Edison, P, Pavese, N, Lockhart, A, Davis, B, Matthews, JC, Quarantelli, M, Laule, C, Vavasour, IM, Kolind, SH, Pasternak, O, Sochen, N, Gur, Y, Intrator, N, Assaf, Y, Andreasen, NC, Ehrhardt, JC, Swayze, VW, Supprian, T, Hofmann, E, Warmuth-Metz, M, Franzek, E, Becker, T, Pfefferbaum, A, Sullivan, EV, Hedehus, M, Moseley, M, Lim, KO, Mandl, RC, Schnack, HG, Luigjes, J, Cahn, W, Bagary, MS, Symms, MR, Barker, GJ, Mutsatsa, SH, Joyce, EM, Ron, MA, Foong, J, Maier, M, Brocklehurst, S, Miller, DH, Kubicki, M, Park, H, Westin, CF, Bouix, S, Dahlben, B, Oestreich, LK, Shenton, ME, Amato, D, Beasley, CL, Hahn, MK, Vernon, AC, Natesan, S, Modo, M, Kapur, S, Mondelli, V, Reininghaus, U, Kempton, MJ, Valmaggia, L, Baumeister, D, Lightman, SL, Pariante, CM, Danese, A, Moffitt, TE, Ambler, A, Poulton, R, Caspi, A, Akhtar, R, Ciufolini, S, Meyer, U, So, PW, Lythgoe, DJ, Cotel, MC, Lenartowicz, EM, Anacker, C, Calcia, MA, Bonsall, DR, Barichello, T, Howes, OD, Burke, NN, Fan, CY, Trang, T, McMahon, SB, Russa, F La, Bennett, DL, Püntener, U, Booth, SG, Perry, VH, Teeling, JL, Hahn, YK, Podhaizer, EM, Farris, SP, Miles, MF, Hauser, KF, Knapp, PE, Notter, T, Gschwind, T, Varga, B, Markó, K, Hádinger, N, Cattaneo, A, Ferrari, C, Uher, R, Belvederi, Murri M, Sandiego, CM, Pittman, B, Weber, MD, Sheridan, JF, Raison, CL, Rutherford, RE, Woolwine, BJ, Möller, T, Boddeke, HW, O'Connor, JC, Lawson, MA, André, C, Hinwood, M, Morandini, J, Day, TA, Walker, FR, Bard, F, Bhattacharya, A, Pae, CU, Marks, DM, Han, C, Patkar, AA, Oya, K, Kishi, T, Iwata, N

Publikováno v: Lancet psychiatry, 0(0), 587-597. Elsevier Limited
Mondelli, V, Vernon, A C, Turkheimer, F E, Dazzan, P & Pariante, C M 2017, ' Brain microglia in psychiatric disorders ', The Lancet Psychiatry, vol. 4, no. 7, pp. 563-572 . https://doi.org/10.1016/S2215-0366(17)30101-3
Mondelli, V, Vernon, A C, Turkheimer, F, Dazzan, P, Pariante, C M, Frost, JL, Schafer, DP, Banati, RB, Newcombe, J, Gunn, RN, al., E, Tang, Y, Le, W, Estes, ML, McAllister, AK, Ransohoff, RM, Davalos, D, Grutzendler, J, Yang, G, al., E, Peferoen, LA, Vogel, DY, Ummenthum, K, al., E, Norden, DM, Trojanowski, PJ, Villanueva, E, Navarro, E, Godbout, JP, Kreisel, T, Frank, MG, Licht, T, al., E, Wachholz, S, Eßlinger, M, Plümper, J, Manitz, MP, Juckel, G, Friebe, A, Trépanier, MO, Hopperton, KE, Mizrahi, R, Mechawar, N, Bazinet, RP, Torres-Platas, SG, Cruceanu, C, Chen, GG, Turecki, G, Mechawar, N, Steiner, J, Bielau, H, Brisch, R, al., E, Schnieder, TP, Trencevska, I, Rosoklija, G, al., E, Fillman, SG, Cloonan, N, Catts, VS, al., E, Rupprecht, R, Papadopoulos, V, Rammes, G, al., E, Qiu, ZK, Li, MS, He, JL, al., E, Hannestad, J, Gallezot, JD, Schafbauer, T, al., E, Israel, I, Ohsiek, A, Al-Momani, E, al., E, Mirzaei, N, Tang, SP, Ashworth, S, al., E, Gulyás, B, Makkai, B, Kása, P, al., E, Turkheimer, FE, Rizzo, G, Bloomfield, PS, al., E, Owen, DR, Yeo, AJ, Gunn, RN, al., E, Hannestad, J, DellaGioia, N, Gallezot, JD, al., E, Setiawan, E, Wilson, AA, Mizrahi, R, al., E, Su, L, Faluyi, YO, Hong, YT, al., E, Haarman, BC, Lek, RF R-V D, Groot, JC D, al., E, Berckel, BN V, Bossong, MG, Boellaard, R, al., E, Doorduin, J, Vries, EF D, Willemsen, AT, Groot, JC D, Dierckx, RA, Klein, HC, Takano, A, Arakawa, R, Ito, H, al., E, Kenk, M, Selvanathan, T, Rao, N, al., E, Bloomfield, PS, Selvaraj, S, Veronese, M, al., E, Coughlin, JM, Wang, Y, Ambinder, EB, al., E, Doef, TF V D, Witte, LD D, Sutterland, AL, al., E, Hafizi, S, Tseng, HH, Rao, N, al., E, Holmes, SE, Hinz, R, Drake, RJ, al., E, Yaqub, M, Berckel, BN V, Schuitemaker, A, al., E, Turkheimer, FE, Edison, P, Pavese, N, al., E, Lockhart, A, Davis, B, Matthews, JC, al., E, Quarantelli, M, Laule, C, Vavasour, IM, Kolind, SH, al., E, Pasternak, O, Sochen, N, Gur, Y, Intrator, N, Assaf, Y, Andreasen, NC, Ehrhardt, JC, Swayze, VW, al., E, Supprian, T, Hofmann, E, Warmuth-Metz, M, Franzek, E, Becker, T, Pfefferbaum, A, Sullivan, EV, Hedehus, M, Moseley, M, Lim, KO, Mandl, RC, Schnack, HG, Luigjes, J, al., E, Mandl, RC, Pasternak, O, Cahn, W, al., E, Bagary, MS, Symms, MR, Barker, GJ, Mutsatsa, SH, Joyce, EM, Ron, MA, Foong, J, Maier, M, Barker, GJ, Brocklehurst, S, Miller, DH, Ron, MA, Foong, J, Symms, MR, Barker, GJ, al., E, Kubicki, M, Park, H, Westin, CF, al., E, Bagary, MS, Foong, J, Maier, M, al., E, Pasternak, O, Westin, CF, Bouix, S, Pasternak, O, Westin, CF, Dahlben, B, Bouix, S, Kubicki, M, Oestreich, LK, Pasternak, O, Shenton, ME, al., E, Amato, D, Beasley, CL, Hahn, MK, Vernon, AC, Vernon, AC, Natesan, S, Modo, M, Kapur, S, Mondelli, V, Reininghaus, U, Kempton, MJ, Valmaggia, L, al., E, Baumeister, D, Lightman, SL, Pariante, CM, Danese, A, Moffitt, TE, Pariante, CM, Ambler, A, Poulton, R, Caspi, A, Baumeister, D, Akhtar, R, Ciufolini, S, Pariante, CM, Mondelli, V, Meyer, U, Vernon, AC, So, PW, Lythgoe, DJ, al., E, Cotel, MC, Lenartowicz, EM, Natesan, S, al., E, Mondelli, V, Anacker, C, Vernon, AC, al., E, Calcia, MA, Bonsall, DR, Bloomfield, PS, Selvaraj, S, Barichello, T, Howes, OD, Burke, NN, Fan, CY, Trang, T, McMahon, SB, Russa, F L, Bennett, DL, Püntener, U, Booth, SG, Perry, VH, Teeling, JL, Hahn, YK, Podhaizer, EM, Farris, SP, Miles, MF, Hauser, KF, Knapp, PE, Notter, T, Coughlin, JM, Gschwind, T, al., E, Varga, B, Markó, K, Hádinger, N, al., E, Cattaneo, A, Ferrari, C, Uher, R, al., E, Mondelli, V, Ciufolini, S, Belvederi, M M, al., E, Sandiego, CM, Gallezot, JD, Pittman, B, al., E, Weber, MD, Godbout, JP, Sheridan, JF, Raison, CL, Rutherford, RE, Woolwine, BJ, al., E, Möller, T, Boddeke, HW, O'Connor, JC, Lawson, MA, André, C, al., E, Hinwood, M, Morandini, J, Day, TA, Walker, FR, Möller, T, Bard, F, Bhattacharya, A, al., E, Pae, CU, Marks, DM, Han, C, Patkar, AA, Oya, K, Kishi, T, Iwata, N, Baumeister, D, Ciufolini, S & Mondelli, V 2016, ' Brain microglia in psychiatric disorders ', Lancet psychiatry, vol. 0, no. 0, pp. 587-597 . https://doi.org/10.1016/S2215-0366(17)30101-3

SummaryThe role of immune activation in psychiatric disorders has attracted considerable attention over the past two decades, contributing to the rise of a new era for psychiatry. Microglia, the macrophages of the brain, are progressively becoming th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1698f7e9b3eca5ef43eb16cacb00b091
https://research.vumc.nl/en/publications/07f168d1-2b4d-4483-b9b1-1659ff4e83f8

Acute neuroimmune stimulation impairs verbal memory in adults: A PET brain imaging study.

Autor: Woodcock EA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States., Hillmer AT; Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, United States., Sandiego CM; Invicro, New Haven, CT, United States., Maruff P; Cogstate Ltd., and The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia., Carson RE; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, United States., Cosgrove KP; Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, United States. Electronic address: kelly.cosgrove@yale.edu., Pietrzak RH; Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States; U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, United States.

Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2021 Jan; Vol. 91, pp. 784-787. Date of Electronic Publication: 2020 Sep 28.

Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [ ¹¹ C]PBR28 HRRT PET study.

Autor: Tuisku J; Turku PET Centre, University of Turku, Turku, Finland. joupes@utu.fi.; Turku PET Centre, c/o Turku University Hospital, Po Box 52, 20521, Turku, Finland. joupes@utu.fi., Plavén-Sigray P; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County, Stockholm, Sweden., Gaiser EC; PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06520, USA.; Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Airas L; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Al-Abdulrasul H; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Brück A; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Carson RE; PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06520, USA., Chen MK; PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06520, USA., Cosgrove KP; PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06520, USA.; Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Ekblad L; Turku PET Centre, University of Turku, Turku, Finland., Esterlis I; Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Farde L; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County, Stockholm, Sweden.; PET Science Centre, Precision Medicine and Genomics, IMED Biotech Unit, AstraZeneca, Karolinska Institutet, Solna, Sweden., Forsberg A; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County, Stockholm, Sweden., Halldin C; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County, Stockholm, Sweden., Helin S; Turku PET Centre, University of Turku, Turku, Finland., Kosek E; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Lekander M; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Stress Research Institute, Department of Psychology, Stockholm University, Stockholm, Sweden., Lindgren N; Turku PET Centre, University of Turku, Turku, Finland., Marjamäki P; Turku PET Centre, University of Turku, Turku, Finland., Rissanen E; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Sucksdorff M; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Varrone A; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County, Stockholm, Sweden.; Stress Research Institute, Department of Psychology, Stockholm University, Stockholm, Sweden., Collste K, Gallezot JD, Hillmer A, Huang Y, Höglund CO, Johansson J, Jucaite A, Lampa J, Nabulsi N, Pittman B, Sandiego CM, Stenkrona P, Rinne J; Turku PET Centre, University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland., Matuskey D; PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06520, USA.; Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Cervenka S; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County, Stockholm, Sweden.

Publikováno v: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2019 Oct; Vol. 46 (11), pp. 2329-2338. Date of Electronic Publication: 2019 Jul 30.

Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers.

Autor: Constantinescu CC; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA. cconstantinescu@invicro.com., Tresse C; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Zheng M; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Gouasmat A; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Carroll VM; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Mistico L; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Alagille D; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Sandiego CM; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Papin C; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Marek K; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Seibyl JP; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA., Tamagnan GD; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA.; Xing Imaging, 760 Temple St., New Haven, CT, 06510, USA., Barret O; Invicro, LLC, 60 Temple St., Suite 8B, New Haven, CT, 06510, USA.

Publikováno v: Molecular imaging and biology [Mol Imaging Biol] 2019 Jun; Vol. 21 (3), pp. 509-518.

In vivo imaging of translocator protein, a marker of activated microglia, in alcohol dependence.

Autor: Hillmer AT; Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.; Yale PET Center, Yale University School of Medicine, New Haven, CT, USA., Sandiego CM; Yale PET Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Hannestad J; UCB Pharma, Braine-l'Alleud, Belgium., Angarita GA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Connecticut Mental Health Center, New Haven, CT, USA., Kumar A; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA., McGovern EM; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Huang Y; Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.; Yale PET Center, Yale University School of Medicine, New Haven, CT, USA., O'Connor KC; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA., Carson RE; Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.; Yale PET Center, Yale University School of Medicine, New Haven, CT, USA., O'Malley SS; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Cosgrove KP; Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.; Yale PET Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USA.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2017 Dec; Vol. 22 (12), pp. 1759-1766. Date of Electronic Publication: 2017 Feb 28.