Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sandi J. Estill-Terpack"'
Autor:
Barbara E. Stopschinski, Sourena Nadji, Jordan G. Finnell, Sandi J. Estill-Terpack, Omar M. Kashmer, Hung S. Luu, Talitha L. Thomas, Eric Darvish, Anuja Modi, Brandon B. Holmes, Hilda Mirbaha, Marc I. Diamond, Linfeng Fan
Publikováno v:
J Biol Chem
Tau aggregation underlies neurodegeneration in Alzheimer's disease and related tauopathies. We and others have proposed that transcellular propagation of pathology is mediated by Tau prions, which are ordered protein assemblies that faithfully replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4aacf11971b9112d93f76e4b02728c
https://europepmc.org/articles/PMC7062170/
https://europepmc.org/articles/PMC7062170/
Autor:
Sandi J. Estill-Terpack, Abigail A. Plec, Ralph J. DeBerardinis, Xiaozheng Zhao, Paul A. Dutchak, Bookyung Ko, Yonghao Yu, Chendong Yang, Benjamin P. Tu, Jun Chen
Publikováno v:
Cell reports
SUMMARY The conserved GATOR1 complex consisting of NPRL2-NPRL3-DEPDC5 inhibits mammalian target of rapamycin complex 1 (mTORC1) in response to amino acid insufficiency. Here, we show that loss of NPRL2 and GATOR1 function in skeletal muscle causes co