Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Sandhya Subramanian"'
Autor:
Jennifer McClure, Aliya Asghar, Anastasia Krajec, Marcus R. Johnson, Sandhya Subramanian, Krissa Caroff, Conor McBurney, Sarah Perusich, Amanda Garcia, Danielle J. Beck, Grant D. Huang
Publikováno v:
Contemporary Clinical Trials Communications, Vol 33, Iss , Pp 101106- (2023)
In the summer of 2020, multiple efforts were undertaken to establish safe and effective vaccines to combat the spread of the coronavirus disease (COVID-19). In the United States (U.S.), Operation Warp Speed (OWS) was the program designated to coordin
Externí odkaz:
https://doaj.org/article/8f483e1eefbe4392ad69b72bd82dfc4d
Autor:
Isabelle Q. Phan, Christopher A. Rice, Justin Craig, Rooksana E. Noorai, Jacquelyn R. McDonald, Sandhya Subramanian, Logan Tillery, Lynn K. Barrett, Vijay Shankar, James C. Morris, Wesley C. Van Voorhis, Dennis E. Kyle, Peter J. Myler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Balamuthia mandrillaris, a pathogenic free-living amoeba, causes cutaneous skin lesions as well as granulomatous amoebic encephalitis, a ‘brain-eating’ disease. As with the other known pathogenic free-living amoebas (Naegleria fowleri an
Externí odkaz:
https://doaj.org/article/2f6501344d864a2aaccaf8376c641a80
Autor:
Isabelle Q. Phan, Sandhya Subramanian, David Kim, Michael Murphy, Deleah Pettie, Lauren Carter, Ivan Anishchenko, Lynn K. Barrett, Justin Craig, Logan Tillery, Roger Shek, Whitney E. Harrington, David M. Koelle, Anna Wald, David Veesler, Neil King, Jim Boonyaratanakornkit, Nina Isoherranen, Alexander L. Greninger, Keith R. Jerome, Helen Chu, Bart Staker, Lance Stewart, Peter J. Myler, Wesley C. Van Voorhis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Rapid generation of diagnostics is paramount to understand epidemiology and to control the spread of emerging infectious diseases such as COVID-19. Computational methods to predict serodiagnostic epitopes that are specific for the pathogen c
Externí odkaz:
https://doaj.org/article/3d810cad4f2b46a1aaf7b89ba641e8bb
Autor:
Logan Tillery, Kayleigh Barrett, Jenna Goldstein, Jared W Lassner, Bram Osterhout, Nathan L Tran, Lily Xu, Ryan M Young, Justin Craig, Ian Chun, David M Dranow, Jan Abendroth, Silvia L Delker, Douglas R Davies, Stephen J Mayclin, Brandy Calhoun, Madison J Bolejack, Bart Staker, Sandhya Subramanian, Isabelle Phan, Donald D Lorimer, Peter J Myler, Thomas E Edwards, Dennis E Kyle, Christopher A Rice, James C Morris, James W Leahy, Roman Manetsch, Lynn K Barrett, Craig L Smith, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0241738 (2021)
Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform
Externí odkaz:
https://doaj.org/article/23d070499b154d11aa93fd5498f6c574
Autor:
Joseph J. Gillespie, Isabelle Q. H. Phan, Holger Scheib, Sandhya Subramanian, Thomas E. Edwards, Stephanie S. Lehman, Hanna Piitulainen, M. Sayeedur Rahman, Kristen E. Rennoll-Bankert, Bart L. Staker, Suvi Taira, Robin Stacy, Peter J. Myler, Abdu F. Azad, Arto T. Pulliainen
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Prokaryotes use type IV secretion systems (T4SSs) to translocate substrates (e.g., nucleoprotein, DNA, and protein) and/or elaborate surface structures (i.e., pili or adhesins). Bacterial genomes may encode multiple T4SSs, e.g., there are th
Externí odkaz:
https://doaj.org/article/eddba446b9474c58833850283358d59e
Autor:
Sushmita Sinha, Lisa M Miller, Sandhya Subramanian, Gregory G Burrows, Arthur A Vandenbark, Halina Offner
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21868 (2011)
Recombinant T cell receptor ligands (RTLs) that target encephalitogenic T-cells can reverse clinical and histological signs of EAE, and are currently in clinical trials for treatment of multiple sclerosis. To evaluate possible regulatory mechanisms,
Externí odkaz:
https://doaj.org/article/efa463d5dd7c4dafa3b1ca06e7763029
Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum
Autor:
Lauryn Brooks, Sandhya Subramanian, David M. Dranow, Stephen J. Mayclin, Peter J. Myler, Oluwatoyin A. Asojo
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 78:306-312
Elizabethkingia bacteria are globally emerging pathogens that cause opportunistic and nosocomial infections, with up to 40% mortality among the immunocompromised. Elizabethkingia species are in the pipeline of organisms for high-throughput structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfdefa8c6db0d1bd44031b6a95dfbec
https://doi.org/10.1107/s2053230x22007555
https://doi.org/10.1107/s2053230x22007555
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 78:52-58
Burkholderia phymatum is an important symbiotic nitrogen-fixing betaproteobacterium. B. phymatum is beneficial, unlike other Burkholderia species, which cause disease or are potential bioagents. Structural genomics studies at the SSGCID include chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e220dc6bf854a75cdd7f26960a25ef
https://doi.org/10.1107/s2053230x22000218
https://doi.org/10.1107/s2053230x22000218
Autor:
Imani Porter, Trinity Neal, Zion Walker, Dylan Hayes, Kayla Fowler, Nyah Billups, Anais Rhoades, Christian Smith, Kaelyn Smith, Bart L. Staker, David M. Dranow, Stephen J. Mayclin, Sandhya Subramanian, Thomas E. Edwards, Peter J. Myler, Oluwatoyin A. Asojo
Publikováno v:
Acta Crystallographica. Section F, Structural Biology Communications
Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis reveal prototypical NADPH-dependent short-chain reductases with structural similarity to protozoan pteridine reductases that are potential drug tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c404dd9cb77044f2aca7976e388dc0c2
https://doi.org/10.1107/s2053230x21013078
https://doi.org/10.1107/s2053230x21013078
Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans
Autor:
Jaysón Davidson, Kyndall Nicholas, Jeremy Young, Deborah G. Conrady, Stephen Mayclin, Sandhya Subramanian, Bart L. Staker, Peter J. Myler, Oluwatoyin A. Asojo
Publikováno v:
Acta Crystallographica. Section F, Structural Biology Communications
The high-resolution structure of a putative short-chain reductase from the commercially important bacterium Paraburkholderia xenovorans is reported. P. xenovorans degrades organic wastes such as polychlorinated biphenyls.
Paraburkholderia xenovo
Paraburkholderia xenovo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396b0ae87a9368c3883f0150f7873155
http://europepmc.org/articles/PMC8725002
http://europepmc.org/articles/PMC8725002