Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Sandhya A. Marathe"'
Autor:
Nandita Sharma, Ankita Das, Abhilash Vijay Nair, Palash Sethi, Vidya Devi Negi, Dipshikha Chakravortty, Sandhya Amol Marathe
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Salmonella, a foodborne pathogen, possesses a type I-E clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated (Cas) system. We investigated the system’s role in regulating Salmonella virulence by de
Externí odkaz:
https://doaj.org/article/c36aedcadaac40fabffe0b39a6be069a
Autor:
Simran Krishnakant Kushwaha, Yi Wu, Hugo Leonardo Avila, Abhirath Anand, Thomas Sicheritz-Pontén, Andrew Millard, Sandhya Amol Marathe, Franklin L Nobrega
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002746 (2024)
Understanding the dynamic evolution of Salmonella is vital for effective bacterial infection management. This study explores the role of the flexible genome, organised in regions of genomic plasticity (RGP), in shaping the pathogenicity of Salmonella
Externí odkaz:
https://doaj.org/article/3a3210342e304ed685354a1ebdc3d0b1
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT The CRISPR-Cas mediated regulation of biofilm by Salmonella enterica serovar Typhimurium was investigated by deleting CRISPR-Cas components ΔcrisprI, ΔcrisprII, ΔΔcrisprI crisprII, and Δcas op. We determined that the system positively r
Externí odkaz:
https://doaj.org/article/34d1412b49ec43139f32adc66c78b756
Publikováno v:
Current Microbiology. 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee86279555808d13ea92137f1301fd9d
https://doi.org/10.1007/s00284-023-03298-w
https://doi.org/10.1007/s00284-023-03298-w
Publikováno v:
Future microbiology. 17
Insights into the arms race between bacteria and invading mobile genetic elements have revealed the intricacies of the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system and the counter-defenses of bacteriophages. Incredibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17663997afec750150978061a0634daf
https://pubmed.ncbi.nlm.nih.gov/36006039
https://pubmed.ncbi.nlm.nih.gov/36006039
Publikováno v:
International Immunology. 33:281-298
Several facets of the host immune response to Salmonella infection have been studied independently at great depths to understand the progress and pathogenesis of Salmonella infection. The circumstances under which a Salmonella-infected individual suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8826fc3c10c8956769c56ac7837446eb
https://doi.org/10.1093/intimm/dxab003
https://doi.org/10.1093/intimm/dxab003
Autor:
Mahipal Reddy Donthi, Siva Ram Munnangi, Kowthavarapu Venkata Krishna, Sandhya Amol Marathe, Ranendra Narayan Saha, Gautam Singhvi, Sunil Kumar Dubey
Publikováno v:
AAPS PharmSciTech. 23(7)
Sorafenib tosylate (SFNT) is the first-line drug for hepatocellular carcinoma. It exhibits poor solubility leading to low oral bioavailability subsequently requiring intake of large quantities of drug to exhibit desired efficacy. The present investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3475dc6ab73d4b5d8bd25ad32b3127
https://pubmed.ncbi.nlm.nih.gov/36109473
https://pubmed.ncbi.nlm.nih.gov/36109473
Autor:
Violina Kakoty, Sarathlal K C, Sunil Kumar Dubey, Chih-Hao Yang, Sandhya Amol Marathe, Rajeev Taliyan
Publikováno v:
Metabolic brain disease. 37(4)
Insulin resistance (IR) and accumulation of amyloid beta (Aβ) oligomers are potential causative factor for Alzheimer's Disease (AD). Simultaneously, enhanced clearance level of these oligomers through autophagy activation bring novel insights into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c44311f225aed0042c606d9271d3c3
https://pubmed.ncbi.nlm.nih.gov/35064868
https://pubmed.ncbi.nlm.nih.gov/35064868
Autor:
Sandhya A. Marathe, Bahaa Abdella, Chandrajit Lahiri, Narra Lakshmi Sai Bhavesh, Simran Krishnakant Kushwaha
Publikováno v:
Scientific Reports
Salmonellae display intricate evolutionary patterns comprising over 2500 serovars having diverse pathogenic profiles. The acquisition and/or exchange of various virulence factors influences the evolutionary framework. To gain insights into evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63386340e8f3a4267451798a253744c
https://doi.org/10.1038/s41598-020-77890-6
https://doi.org/10.1038/s41598-020-77890-6