Let-7i Reduces Aggressive Phenotype and Induces BRCAness in Ovarian Cancer Cells.

Autor: Chirshev E; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA.; Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA., Suzuki T; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA., Wang H; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA., Nguyen A; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA., Hojo N; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA., Sanderman L; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA.; Biology Department, California State University San Bernardino, San Bernardino, CA 92407, USA., Mirshahidi S; Biospecimen Laboratory, Loma Linda University Cancer Center, Department of Basic Sciences, Division of Microbiology & Molecular Genetics, Loma Linda University, Loma Linda, CA 92354, USA., Ioffe YJ; Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA., Unternaehrer JJ; Department of Basic Sciences, Division of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA.; Department of Gynecology and Obstetrics, Loma Linda University, Loma Linda, CA 92354, USA.; Center for Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA 92354, USA.

Publikováno v: Cancers [Cancers (Basel)] 2021 Sep 15; Vol. 13 (18). Date of Electronic Publication: 2021 Sep 15.

Epithelial/mesenchymal heterogeneity of high-grade serous ovarian carcinoma samples correlates with miRNA let-7 levels and predicts tumor growth and metastasis.

Autor: Chirshev E; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA.; Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA, USA., Hojo N; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA., Bertucci A; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA., Sanderman L; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA.; Biology Department, California State University San Bernardino, San Bernardino, CA, USA., Nguyen A; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA., Wang H; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA., Suzuki T; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA., Brito E; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA.; Biology Department, California State University San Bernardino, San Bernardino, CA, USA., Martinez SR; Center for Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA, USA., Castañón C; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA.; Center for Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA, USA., Mirshahidi S; Biospecimen Laboratory, Division of Microbiology & Molecular Genetics, Department of Basic Sciences, Loma Linda University Cancer Center, Loma Linda University, Loma Linda, CA, USA., Vazquez ME; Department of Radiation Medicine, Loma Linda University, Loma Linda, CA, USA., Wat P; Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA, USA., Oberg KC; Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA, USA., Ioffe YJ; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Loma Linda University Medical Center, Loma Linda, CA, USA., Unternaehrer JJ; Division of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA.; Center for Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA, USA.; Department of Gynecology and Obstetrics, Loma Linda University, Loma Linda, CA, USA.

Publikováno v: Molecular oncology [Mol Oncol] 2020 Nov; Vol. 14 (11), pp. 2796-2813. Date of Electronic Publication: 2020 Aug 21.

A Stem-like Patient-Derived Ovarian Cancer Model of Platinum Resistance Reveals Dissociation of Stemness and Resistance.

Autor: Suzuki, Tise¹ (AUTHOR) tsuzuki@students.llu.edu, Conant, Ashlyn¹ (AUTHOR) abartlett@students.llu.edu, Jung, Yeonkyu^1,2 (AUTHOR) yeonkyujung@llu.edu, Bax, Ryan¹ (AUTHOR) rbax@students.llu.edu, Antonissen, Ashley^1,2 (AUTHOR) ashleyantonissen@llu.edu, Chen, Wanqiu^1,3 (AUTHOR) wchen@llu.edu, Yu, Gary⁴ (AUTHOR) gy2153@columbia.edu, Ioffe, Yevgeniya J.⁵ (AUTHOR) yioffe@llu.edu, Wang, Charles^1,3 (AUTHOR) chwang@llu.edu, Unternaehrer, Juli J.^1,5 (AUTHOR) junternaehrer@llu.edu

Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 7, p3843. 21p.

Mechanisms of Regulation of the Expression of miRNAs and lncRNAs by Metformin in Ovarian Cancer.

Autor: Alfaro, Ignacio¹ (AUTHOR), Vega, Margarita^1,2 (AUTHOR), Romero, Carmen^1,2 (AUTHOR) cromero@hcuch.cl, Garrido, Maritza P.^1,2 (AUTHOR) cromero@hcuch.cl

Publikováno v: Pharmaceuticals (14248247). Nov2023, Vol. 16 Issue 11, p1515. 19p.

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