Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Sander S Korevaar"'
Autor:
Ana Merino, Martin J Hoogduijn, Maria Molina-Molina, Elena G Arias-Salgado, Sander S Korevaar, Carla C Baan, Ana Montes-Worboys
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248415 (2021)
BackgroundIdiopathic pulmonary fibrosis (IPF) is a devastating lung disease with limited treatment options in which the telomere shortening is a strong predictive factor of poor prognosis. Mesenchymal stromal cells (MSC) administration is probed in s
Externí odkaz:
https://doaj.org/article/9381368e7f854d9b9633a48a913e8ca2
Autor:
Anusha S. Shankar, Hector Tejeda-Mora, Zhaoyu Du, Quincy Nlandu, Virginia Palomares-Cabeza, Thierry P. P. van den Bosch, Sander S. Korevaar, Fabiany Da Costa Gonçalves, Eric M. J. Bindels, R. Kramann, Marlies E. J. Reinders, Marian C. Clahsen-van Groningen, Ewout J. Hoorn, Joost Gribnau, Carla C. Baan, Martin J. Hoogduijn
Publikováno v:
Transplant International, Vol 37 (2024)
Kidney organoids are an innovative tool in transplantation research. The aim of the present study was to investigate whether kidney organoids are susceptible for allo-immune attack and whether they can be used as a model to study allo-immunity in kid
Externí odkaz:
https://doaj.org/article/3cc42c074ba04f7f8e9f53cc968ab725
Autor:
Anusha S Shankar, Zhaoyu Du, Hector Tejeda Mora, Ruben Boers, Wanlu Cao, Thierry P P van den Bosch, Sander S Korevaar, Joachim Boers, Wilfred F J van IJcken, Eric M J Bindels, Bert Eussen, Annelies de Klein, Qiuwei Pan, Lindsey Oudijk, Marian C Clahsen-van Groningen, Ewout J Hoorn, Carla C Baan, Joost Gribnau, Martin J Hoogduijn
Publikováno v:
Stem Cells, 40(6), 577-591. Wiley-Blackwell
Induced pluripotent stem cell (iPSC)-derived kidney organoids are a potential tool for the regeneration of kidney tissue. They represent an early stage of nephrogenesis and have been shown to successfsully vascularize and mature further in vivo. Howe
Autor:
Marian C. Clahsen-van Groningen, Carla C. Baan, Thierry P P van den Bosch, Hui Lin, Joost Gribnau, Anusha S. Shankar, Sander S. Korevaar, Hector Tejeda Mora, Sjoerd A A van den Berg, Martin J. Hoogduijn, Ewout J. Hoorn, Ronald van der Wal, Zhaoyu Du
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association-European Renal Association, 37(1), 190-193. Oxford University Press
Human kidney organoids possess early glomerular and tubular function. However, little is known about their hormone producing ability. In this report, we show that kidney organoids take up and metabolize inactive 25(OH) vitamin D (25(OH)D3). Uptake of
Autor:
Marlies E J Reinders, Zhaoyu Du, Marian C. Clahsen-van Groningen, Carla C. Baan, Thierry P P van den Bosch, Anusha S. Shankar, Joost Gribnau, Martin J. Hoogduijn, Ewout J. Hoorn, Sander S. Korevaar
Publikováno v:
Stem Cells and Development, 30(22), 1103-1114. Mary Ann Liebert Inc.
Human-induced pluripotent stem cell (iPSC)-derived kidney organoids have the potential to advance studies to kidney development and disease. However, reproducible generation of kidney organoids is a challenge. A large variability in the percentage of
Autor:
Yongkang Wu, Martin J. Hoogduijn, Carla C. Baan, Sander S. Korevaar, Ronella de Kuiper, Lin Yan, Lanlan Wang, Nicole M. van Besouw
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Mesenchymal stem cells derived from adipose tissue (ASC) have immune regulatory function, which makes them interesting candidates for cellular therapy. ASC cultures are however heterogeneous in phenotype. It is unclear whether all ASC contribute equa
Externí odkaz:
https://doaj.org/article/480732abfc974a11a847a2710a2afd5e
Autor:
Eric Bindels, Anusha S. Shankar, Carmen López-Iglesias, Hector Tejeda Mora, Ingrid M. Van den Berg-Garrelds, Marian C. Clahsen-van Groningen, A.H. Jan Danser, Martin J. Hoogduijn, Ewout J. Hoorn, Carla C. Baan, Thierry P P van den Bosch, Zhaoyu Du, Sander S. Korevaar, Joost Gribnau
Publikováno v:
Kidney International, 99(1), 134-147. Elsevier Science
Kidney International, 99(1), 134-147. Elsevier Inc.
Kidney International, 99(1), 134-147. Elsevier Inc.
Renin production by the kidney is of vital importance for salt, volume, and blood pressure homeostasis. The lack of human models hampers investigation into the regulation of renin and its relevance for kidney physiology. To develop such a model, we u
Autor:
Martin J. Hoogduijn, Sander S. Korevaar, Olivia J. Lee, Andreas R. R. Weiss, Marc H. Dahlke, Elke Eggenhofer, Yorick Soeder, Elisabeth Geissler, Hans J. Schlitt, Edward K. Geissler
Publikováno v:
Stem Cells, 38(6), 797-807. Wiley-Blackwell
Mesenchymal stem cells (MSCs) are used in various clinical and preclinical models for immunomodulation. However, it remains unclear how the immunomodulatory effect of MSC is communicated. MSC-induced immunomodulation is known to be mediated through b
Autor:
Ana Merino, Maitane Ortiz-Virumbrales, Sander S. Korevaar, Carmen López-Iglesias, Martin J. Hoogduijn, Eleuterio Lombardo, Carla C. Baan, Marta Sablik
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology, 12:650522. Frontiers Media S.A.
Frontiers in Immunology
Frontiers in Immunology, 12:650522. Frontiers Media S.A.
Proinflammatory stimuli lead to endothelial injury, which results in pathologies such as cardiovascular diseases, autoimmune diseases, and contributes to alloimmune responses after organ transplantation. Both mesenchymal stromal cells (MSC) and the e
Autor:
Martin J. Hoogduijn, Maitane Ortiz Virumbrales, Carla C. Baan, Ana Merino, Eleuterio Lombardo, Fabiany da Costa Gonçalves, Sander S. Korevaar, Marlies E J Reinders
Publikováno v:
Frontiers in Immunology, 12:651109. Frontiers Media S.A.
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Mesenchymal stromal cells (MSC) are a promising therapy for inflammatory diseases. However, MSC are large and become trapped in the lungs after intravenous infusion, where they have a short survival time. To steer MSC immunoregulatory therapy beyond