Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sander Kelderman"'
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Supplementary Figure 3. KLH-specific immune responses before and after DC vaccination. (A) KLH-specific T cell proliferation was analyzed before the first vaccination and after each DC vaccination during the first vaccination cycle in peripheral bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce748475936725a8bb47b16d85c4c40
https://doi.org/10.1158/1078-0432.22457933.v1
https://doi.org/10.1158/1078-0432.22457933.v1
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Purpose: Thus far, dendritic cell (DC)-based immunotherapy of cancer was primarily based on in vitro–generated monocyte-derived DCs, which require extensive in vitro manipulation. Here, we report on a clinical study exploiting primary CD1c+ myeloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492a00959142946a6e6448b4074be089
https://doi.org/10.1158/1078-0432.c.6523763.v1
https://doi.org/10.1158/1078-0432.c.6523763.v1
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Supplementary Figure 1. Schematic overview of the 44 h mDC vaccine preparation cycle and vaccination strategy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d06d6192c935b44e17609dce62fe016
https://doi.org/10.1158/1078-0432.22457939
https://doi.org/10.1158/1078-0432.22457939
Autor:
Daniel J. Powell, Nathalie Scholler, Jason Yu, Sander Kelderman, Brian P. Gavin, Rachel C. Lynn, Mathilde Poussin, Evripidis Lanitis, Katarzyna Urbanska
PDF file - 113K, Flow Cytometry analysis of an antigen surface expression on mouse AE17 cell lines transduced to express human FR�� or mesothelin and human ovarian cancer cell line, A1847. FR��-specific mAb Mov18, EpCAM-specific and mesotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45eb3117cc24b5a88bdcaea3d652b95f
https://doi.org/10.1158/0008-5472.22394861.v1
https://doi.org/10.1158/0008-5472.22394861.v1
Autor:
Daniel J. Powell, Nathalie Scholler, Jason Yu, Sander Kelderman, Brian P. Gavin, Rachel C. Lynn, Mathilde Poussin, Evripidis Lanitis, Katarzyna Urbanska
PDF file - 21K, BBIR-z T cells loaded with biotinylated molecules and then washed do not produce IFN�� in response to specific antigen stimulation. Following 45min incubation at 37oC with 1ug/ml of mesothelin specific biotinylated antybodies; P4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd33294af1fc51abd7d28c11c1770d1
https://doi.org/10.1158/0008-5472.22394864
https://doi.org/10.1158/0008-5472.22394864
Autor:
Daniel J. Powell, Nathalie Scholler, Jason Yu, Sander Kelderman, Brian P. Gavin, Rachel C. Lynn, Mathilde Poussin, Evripidis Lanitis, Katarzyna Urbanska
PDF file - 67K, Upper. CD28 co-stimulation protects against antigen-induced cell death. Annexin V and 7-AAD staining of T cells (untransduced, BBIR-z and BBIR-28z) following 72 h (grey bars) and 96 h (black bars) co-culture with A1847 at an E:T ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171b843b2f8f36266a1693bdd4f26985
https://doi.org/10.1158/0008-5472.22394867.v1
https://doi.org/10.1158/0008-5472.22394867.v1
Autor:
Sander Kelderman, Tjibbe Veenema
Publikováno v:
Tandartspraktijk. 41:13-17
In Nederland vinden jaarlijks tussen de 165.000 en 185.000 bevallingen plaats.1 De gemiddelde tandartspraktijk ziet dan ook met enige regelmaat zwangere patienten. De meeste zwangeren zijn zich bewust van hun zwangerschap en zullen deze melden bij aa
Autor:
Gavin M. Bendle, Roelof J.C. Kluin, Wouter Scheper, Petur Snaebjornsson, Carsten Linnemann, Gemma G. Kenter, Marije A. J. de Rooij, John B. A. G. Haanen, Riccardo Mezzadra, Christian Hirt, Ton N. Schumacher, Emile E. Voest, Sander Kelderman, Krijn K. Dijkstra, Brad H. Nelson, Maarten Slagter, Lorenzo F. Fanchi, Katy Milne, Henry Zijlmans
Publikováno v:
Nature medicine, 25(1), 89-94. Nature Publishing Group
Infiltration of human cancers by T cells is generally interpreted as a sign of immune recognition, and there is a growing effort to reactivate dysfunctional T cells at such tumor sites1. However, these efforts only have value if the intratumoral T ce
Autor:
Sander Kelderman, Stieneke van den Brink, Ton N. Schumacher, Nienke van Rooij, Sovann Kaing, Lorenzo F. Fanchi, Emile E. Voest, Chiara M Cattaneo, Krijn K. Dijkstra
Publikováno v:
Nat Protoc
T cells are a key player in cancer immunotherapy, but strategies to expand tumor-reactive cells and study their interaction with tumor cells at the level of an individual patient are limited. This protocol describes the generation and functional asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010f51d68bb26e76f05cc6a1efdedd62
https://europepmc.org/articles/PMC7610702/
https://europepmc.org/articles/PMC7610702/
Antigen-specific TIL therapy for melanoma: A flexible platform for personalized cancer immunotherapy
Autor:
Lorenzo F. Fanchi, Sander Kelderman, Nienke van Rooij, Samira Michels, John B. A. G. Haanen, Mireille Toebes, Pia Kvistborg, Bianca Heemskerk, Marit M. van Buuren, N. M. Schumacher, Lothar Germeroth, Daisy Philips
Publikováno v:
European Journal of Immunology. 46:1351-1360
Tumor infiltrating lymphocyte (TIL) therapy has shown objective clinical response rates of 50% in stage IV melanoma patients in a number of clinical trials. Nevertheless, the majority of patients progress either directly upon therapy or after an init