Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sander K Govers"'
Autor:
Manuel Campos, Sander K Govers, Irnov Irnov, Genevieve S Dobihal, François Cornet, Christine Jacobs‐Wagner
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 6, Pp 1-21 (2018)
Abstract Cell size, cell growth, and cell cycle events are necessarily intertwined to achieve robust bacterial replication. Yet, a comprehensive and integrated view of these fundamental processes is lacking. Here, we describe an image‐based quantit
Externí odkaz:
https://doaj.org/article/94bfc580482c44cb9cc54078279fe652
Autor:
Bram Cerulus, Abbas Jariani, Gemma Perez-Samper, Lieselotte Vermeersch, Julian MJ Pietsch, Matthew M Crane, Aaron M New, Brigida Gallone, Miguel Roncoroni, Maria C Dzialo, Sander K Govers, Jhana O Hendrickx, Eva Galle, Maarten Coomans, Pieter Berden, Sara Verbandt, Peter S Swain, Kevin J Verstrepen
Publikováno v:
eLife, Vol 7 (2018)
Cells constantly adapt to environmental fluctuations. These physiological changes require time and therefore cause a lag phase during which the cells do not function optimally. Interestingly, past exposure to an environmental condition can shorten th
Externí odkaz:
https://doaj.org/article/7c1e0af6819f423abf8a88b48065c0d4
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2003853 (2018)
Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a stress- or age-associated decline in cellular proteostasis. A careful reassessment of this paradigm in the E. coli model bacterium revealed t
Externí odkaz:
https://doaj.org/article/ed553c5cdfe140749c1b9da819fca870
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005770 (2015)
Monitoring the complex transmission dynamics of a bacterial virus (temperate phage P22) throughout a population of its host (Salmonella Typhimurium) at single cell resolution revealed the unexpected existence of a transiently immune subpopulation of
Externí odkaz:
https://doaj.org/article/2a9ccd7bfabb4da0b452f65043a9556b
Autor:
Aaron M New, Bram Cerulus, Sander K Govers, Gemma Perez-Samper, Bo Zhu, Sarah Boogmans, Joao B Xavier, Kevin J Verstrepen
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001764 (2014)
Organisms respond to environmental changes by adapting the expression of key genes. However, such transcriptional reprogramming requires time and energy, and may also leave the organism ill-adapted when the original environment returns. Here, we stud
Externí odkaz:
https://doaj.org/article/a1d9798d97464802ae637b7fa65fec36
Autor:
Michaël Deghelt, Seung-Hyun Cho, Sander K. Govers, Arne Janssens, Alix Dachsbeck, Han K. Remaut, Jean-François Collet
Bacteria are subject to a substantial concentration differential of osmolytes between the interior and exterior of the cell, which results in cytoplasmic turgor pressure. Failure to mechanically balance turgor pressure causes cells to burst. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c89a85559e9e8a07695f19c668adb95
https://doi.org/10.1101/2023.04.29.538579
https://doi.org/10.1101/2023.04.29.538579
Autor:
Mara Del Vecchio, Lucia Amado, Alexandra P. Cogan, Els Meert, Joelle Rosseels, Vanessa Franssens, Sander K. Govers, Joris Winderickx, Ayelén González Montoro
Publikováno v:
Molecular Biology of the Cell.
The protein alpha-synuclein (α-syn) is one of the major factors linked to Parkinson's disease, yet how its misfolding and deposition contribute to the pathology remains largely elusive. Recently, contact sites among organelles were implicated in the
SummaryTo examine how bacteria achieve robust cell proliferation across diverse conditions, we developed a method that quantifies 77 cell morphological, cell cycle and growth phenotypes of a fluorescently-labeledEscherichia colistrain and >800 gene d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25b1b84020424b465ab62746d437b12
https://doi.org/10.2139/ssrn.4330683
https://doi.org/10.2139/ssrn.4330683
Publikováno v:
STAR protocols. 3(3)
Given the low fraction of antibiotic-tolerant persisters and the transient nature of the persister phenotype, identifying molecular mechanisms underlying persister state exit, also called "awakening," is challenging. Here, we describe how persister a
Publikováno v:
Current Biology. 30:R1151-R1158
In scientific research, we often rely on well-established model systems to tackle important questions. In this context, extensive characterization of specific bacterial species such as Escherichia coli and Bacillus subtilis has provided a vast amount