Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sander Basten"'
Autor:
Sander Basten, Nataliia Beztsinna, Kuan Yan, Niels Meesters, Emma Spanjaard, Leo Price, Talita Stessuk, Ezgi Kaya Aksoy
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/77c207fa48c14253965e1a70145beb35
Autor:
Gera Goverse, Sander Basten, Leo Price, Saskia de Man, Chiara Foini, Tomas Veenendaal, Sergei Chavez-Abiega, Michelle Kop, Rick Heeren, Christos Sarantaris, Daniel Okkes, Ashgard Weterings
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1ee6319ab5414055a667ff6c0b03d623
Autor:
Kevin Litchfield, Max Levy, Darshna Dudakia, Paula Proszek, Claire Shipley, Sander Basten, Elizabeth Rapley, D. Timothy Bishop, Alison Reid, Robert Huddart, Peter Broderick, David Gonzalez de Castro, Simon O'Connor, Rachel H. Giles, Richard S. Houlston, Clare Turnbull
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
There is some evidence of a hereditary risk for developing testicular germ cell tumours. Here, the authors use whole-exome sequencing and identify a risk variant for the disease in DNAAF1, a gene involved in microtubule-based cilia.
Externí odkaz:
https://doaj.org/article/5514be44ed294c9ca7423b116df904dc
Autor:
Sander Basten, Nataliia Beztsinna, Fanny Grillet, Kuan Yan, Niels Meesters, Donny van der Meer, Emma Spanjaard, Willemijn Vader, Leo Price
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Nataliia Beztsinna, Sander Basten, Ezgi Kaya Aksoy, Niels Meesters, Stefanos Timiliotis, Donny van der Meer, Kuan Yan, Emma Spanjaard, Willemijn Vader, Leo S. Price
Publikováno v:
Cancer Research. 83:4570-4570
Introduction: The fast-paced (immuno)-oncology drug development pipeline requires sophisticated and reliable in vitro models to accurately represent all players of complex human tumor microenvironment (TME). Our 3D Ex Vivo Patient Tissue (EVPT) platf
Autor:
Fanny Grillet, Leo S. Price, Daphne Dumouline, Willemijn Vader, Jan vd Thusen, Kuan Yan, Robin Cornelissen, Sander Basten
Publikováno v:
Cancer Research. 79:55-55
Background Malignant pleural mesothelioma (MPM) is almost exclusively linked to asbestos exposure with a latency period that is usually more than 30 years. Once diagnosis is made, the prognosis is poor. Systemic treatment combines an antifolate combi
Autor:
Julia Schueler, Leo S. Price, Kuan Yan, Thomas Dijkmans, Bram Herpers, Sander Basten, Torsten Giesemann
Publikováno v:
Cancer Research. 78:LB-036
Creating patient-derived xenograft (PDX) models from human cancers allows bio-banking, propagation, characterization and drug testing on a large panel of tumor variants. We developed 3D in vitro culture methods for PDX model-derived cell isolates. Ea
Autor:
Kuan Yan, Bram Herpers, Thomas Dijkmans, Julia Schueler, Sander Basten, Torsten Giesemann, Willemijn Vader, Leo S. Price
Publikováno v:
Cancer Research. 78:4644-4644
Ex vivo cultures of patient-derived tumor enable functional testing of treatment options and optimization of pre-clinical drug development. Patient biopsies or tumor from patient-derived xenografts (PDX) mouse models are a valuable source of human tu
Publikováno v:
Molecular Cancer Therapeutics. 17:LB-A09
Ex vivo culture of patient derived tumor material has broad applications including functional testing to support treatment decisions, as well as testing drugs in development. Because average therapeutic response rates are low, there is a need for cli
Autor:
Leo S. Price, Bram Herpers, Sander Basten, Torsten Giesemann, Julia Schueler, Kuan Yan, Thomas Dijkmans
Publikováno v:
Molecular Cancer Therapeutics. 17:LB-A18
Creating patient-derived xenograft (PDX) models from human cancers allows bio-banking, propagation, characterization and drug testing on a large panel of tumor variants. To scale up the number of compound tests, identify relevant compound doses, incr