P1500: WHAT’S DRIVING RDW? IN-VITRO AND IN-SILICO EVIDENCE FOR OXIDATIVE STRESS

Autor: Huibert-Jan Joosse, Brigitte van Oirschot, Sander A.A. Kooijmans, Imo E Hoefer, Richard A.H. Van Wijk, Albert Huisman, Wouter W Van Solinge, Saskia Haitjema

Publikováno v: HemaSphere, Vol 7, p e76637bf (2023)

Externí odkaz: https://doaj.org/article/8e149621927f40bba6bbab7a3e7e0479

The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis

Autor: Susan M. van Dommelen, Raya Sorkin, Richard van Wijk, Marc Bierings, Birgitta Versluijs, Jürgen Schiller, Raymond M. Schiffelers, Brigitte A. van Oirschot, Sander T. Döpp, Daan Vorselen, Gijs J.L. Wuite, Melissa C. Piontek, Wouter H. Roos, Sander A.A. Kooijmans

Publikováno v: Nature Communications, 9(1):4960. Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications, 9(1). Nature Publishing Group
Vorselen, D, van Dommelen, S M, Sorkin, R, Piontek, M C, Schiller, J, Döpp, S T, Kooijmans, S A A, van Oirschot, B A, Versluijs, B A, Bierings, M B, van Wijk, R, Schiffelers, R M, Wuite, G J L & Roos, W H 2018, ' The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis ', Nature Communications, vol. 9, 4960, pp. 1-9 . https://doi.org/10.1038/s41467-018-07445-x
Nature Communications, 9:4960, 1-9. Nature Publishing Group

Extracellular vesicles (EVs) are widely studied regarding their role in cell-to-cell communication and disease, as well as for applications as biomarkers or drug delivery vehicles. EVs contain membrane and intraluminal proteins, affecting their struc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe7a80da8f3c96a37e3ede779e4c0b3
http://www.scopus.com/inward/record.url?scp=85057079300&partnerID=8YFLogxK

Drug Delivery with Extracellular Vesicles: From Imagination to Innovation

Autor: Joost P.G. Sluijter, Linglei Jiang, Raymond M. Schiffelers, Daniel E. Murphy, Sander A.A. Kooijmans, Olivier G. de Jong, Martijn J W Evers, Pieter Vader

Publikováno v: Accounts of Chemical Research

[Image: see text] Extracellular vesicles are nanoparticles produced by cells. They are composed of cellular membrane with associated membrane proteins that surrounds an aqueous core containing soluble molecules such as proteins and nucleic acids, lik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f79b9c44bab21c43fd6245034db7b5c
https://europepmc.org/articles/PMC6639984/

In Situ Gelling Liquid Crystalline System as Local siRNA Delivery System

Autor: Fabiana T. M. C. Vicentini, Márcia Carvalho de Abreu Fantini, Roy van der Meel, Maria Vitória Lopes Badra Bentley, Sander A.A. Kooijmans, Raymond M. Schiffelers, Marcel H.A.M. Fens, Lívia Neves Borgheti-Cardoso

Publikováno v: Molecular pharmaceutics, 14(5), 1681. American Chemical Society
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

An effective short interfering RNA (siRNA) delivery system protects the siRNA from degradation, facilitates its cellular uptake, and promotes its release into the cytoplasm. Local administration of siRNA presents advantages over systemic administrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be380f601084a0764b5a034967d5d1e
https://dspace.library.uu.nl/handle/1874/355863

A Solid-Phase Platform for Combinatorial and Scarless Multipart Gene Assembly

Autor: Markus de Raad, Sander A.A. Kooijmans, Erik A. Teunissen, Enrico Mastrobattista

Publikováno v: ACS Synthetic Biology. 2:316-326

With the emergence of standardized genetic modules as part of the synthetic biology toolbox, the need for universal and automatable assembly protocols increases. Although several methods and standards have been developed, these all suffer from drawba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f558e2327f6e3242e48b3bf0cd07a4
https://doi.org/10.1021/sb300122q