Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Sander, Grefte"'
Autor:
Miranda van der Ende, Rogier L. C. Plas, Miriam van Dijk, Jvalini T. Dwarkasing, Frans van Gemerden, Attusa Sarokhani, Hans J. M. Swarts, Evert M. van Schothorst, Sander Grefte, Renger F. Witkamp, Klaske van Norren
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Targeted exercise combined with nutritional and pharmacological strategies is commonly considered to be the most optimal strategy to reduce the development and progression of cachexia. For COPD patients, this multi-targeted treatment has sho
Externí odkaz:
https://doaj.org/article/f1eb2fda6cae4e09a407a64c19271994
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Mitochondria are cellular organelles that control metabolic homeostasis and ATP generation, but also play an important role in other processes, like cell death decisions and immune signaling. Mitochondria produce a diverse array of metabolites that a
Externí odkaz:
https://doaj.org/article/2c9b3e012d0b4f549084fa49b6c10821
Autor:
Lonneke M. JanssenDuijghuijsen, Sander Grefte, Vincent C. J. de Boer, Lara Zeper, Dorien A. M. van Dartel, Inge van der Stelt, Melissa Bekkenkamp-Grovenstein, Klaske van Norren, Harry J. Wichers, Jaap Keijer
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Objective:In vivo studies suggest that intestinal barrier integrity is dependent on mitochondrial ATP production. Here, we aim to provide mechanistic support, using an in vitro model mimicking the oxidative in vivo situation.Methods: Human Caco-2 cel
Externí odkaz:
https://doaj.org/article/83d9c55078fa494abce1f2cf49cd83a0
Autor:
Albert Quintana, Judith Homberg, Merel J. W. Adjobo-Hermans, Mariusz R. Wieckowski, Sander Grefte, Melissa van de Wal, Jaap Keijer, Werner J H Koopman, Evert M. van Schothorst, Clara D.M. van Karnebeek, Tom J.J. Schirris
Publikováno v:
Brain, 145, 1, pp. 45-63
Brain, 145, 45-63
Brain, 145(1), 45-63
Brain, 145(1), 45-63. Oxford University Press
Brain 145 (2022) 1
Brain, 145, 45-63
Brain, 145(1), 45-63
Brain, 145(1), 45-63. Oxford University Press
Brain 145 (2022) 1
Mitochondria are small cellular constituents that generate cellular energy (ATP) by oxidative phosphorylation (OXPHOS). Dysfunction of these organelles is linked to a heterogeneous group of multisystemic disorders, including diabetes, cancer, ageing-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29f553cee4ad34628f044c06a43ee8b
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e114090 (2014)
Opening of the mitochondrial permeability transition pore (mPTP) is involved in various cellular processes including apoptosis induction. Two distinct states of mPTP opening have been identified allowing the transfer of molecules with a molecular wei
Externí odkaz:
https://doaj.org/article/52a5cd44d6bf4a259d5882e2233fb432
Autor:
Sander, Grefte, Werner J H, Koopman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2275
Reactive oxygen species (ROS) play an important role in cellular (patho)physiology. Empirical evidence suggests that mitochondria are an important source of ROS, especially under pathological conditions. Here, we describe a method for ROS measurement
Autor:
Evert M. van Schothorst, Renger F. Witkamp, Jvalini Dwarkasing, Hans J. M. Swarts, Rogier L. C. Plas, Frans van Gemerden, Miranda van der Ende, Miriam van Dijk, Attusa Sarokhani, Sander Grefte, Klaske van Norren
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports 11 (2021)
Scientific Reports, 11
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports 11 (2021)
Scientific Reports, 11
Targeted exercise combined with nutritional and pharmacological strategies is commonly considered to be the most optimal strategy to reduce the development and progression of cachexia. For COPD patients, this multi-targeted treatment has shown benefi
Autor:
Werner J H Koopman, Sander Grefte
Publikováno v:
MIMB ; 2275, 291-299. [S.l.] : Springer
STARTPAGE=291;ENDPAGE=299;TITLE=MIMB ; 2275
Methods in Molecular Biology, pp. 291-299
Methods in Molecular Biology ISBN: 9781071612613
Mitochondrial Medicine. New York: Humana Press Inc.
Mitochondrial Medicine
STARTPAGE=291;ENDPAGE=299;TITLE=MIMB ; 2275
Methods in Molecular Biology, pp. 291-299
Methods in Molecular Biology ISBN: 9781071612613
Mitochondrial Medicine. New York: Humana Press Inc.
Mitochondrial Medicine
Item does not contain fulltext Reactive oxygen species (ROS) play an important role in cellular (patho)physiology. Empirical evidence suggests that mitochondria are an important source of ROS, especially under pathological conditions. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dd38880bbf199bb855f2e682197112
http://hdl.handle.net/2066/235653
http://hdl.handle.net/2066/235653
Autor:
Paola L Carvajal Monroy, Sander Grefte, Anne M Kuijpers-Jagtman, Maria P A C Helmich, Dietmar J O Ulrich, Johannes W Von den Hoff, Frank A D T G Wagener
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59193 (2013)
BACKGROUND: Children with a cleft in the soft palate have difficulties with speech, swallowing, and sucking. Despite successful surgical repositioning of the muscles, optimal function is often not achieved. Scar formation and defective regeneration m
Externí odkaz:
https://doaj.org/article/c2822e04b6034c45a56ba032214e4dba
Autor:
Renger F. Witkamp, Klaske van Norren, Jocelijn Meijerink, Jaap Keijer, Miranda van der Ende, Rogier L. C. Plas, Sander Grefte
Publikováno v:
Biochimica et Biophysica Acta-Reviews on Cancer, 1870(2), 137-150
Biochimica et Biophysica Acta-Reviews on Cancer 1870 (2018) 2
Biochimica et Biophysica Acta-Reviews on Cancer 1870 (2018) 2
Cancer-induced cachexia has a negative impact on quality of life and adversely affects therapeutic outcomes and survival rates. It is characterized by, often severe, loss of muscle, with or without loss of fat mass. Insight in the pathophysiology of