Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sandeep Swargam"'
Autor:
Syeda Mobeen Anjum, Katari Sudheer Kumar, Amineni Umamaheswari, Dinesh Lakhanpal, Sandeep Swargam, Khateef Riazunnisa, Thummala Chandrasekhar
Publikováno v:
Results in Chemistry, Vol 5, Iss , Pp 100970- (2023)
The transcription factor family includes the cluster protein signal transducer and activator of transcription 3 (STAT3). Colorectal cancer (CRC) is predisposed to develop and spread when STAT 3 is abnormally activated because it speeds up cell divisi
Externí odkaz:
https://doaj.org/article/b1d2953e3c084fd98e6e198651a13391
Autor:
Sandeep Swargam, Indu Kumari, Amit Kumar, Dibyabhaba Pradhan, Anwar Alam, Harpreet Singh, Anuja Jain, Kangjam Rekha Devi, Vishal Trivedi, Jogesh Sarma, Mahmud Hanif, Kanwar Narain, Nasreen Zafar Ehtesham, Seyed Ehtesham Hasnain, Shandar Ahmad
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2022)
Whole-genome sequencing (WGS) provides a comprehensive tool to analyze the bacterial genomes for genotype–phenotype correlations, diversity of single-nucleotide variant (SNV), and their evolution and transmission. Several online pipelines and stand
Externí odkaz:
https://doaj.org/article/74355113318c4592be25dd529806cac1
Publikováno v:
Current Protein & Peptide Science. 24:229-239
Abstract: Leishmaniasis is the second deadliest vector-borne, neglected tropical zoonotic disease and is found in a variety of clinical forms based on genetic background. Its endemic type is present in tropical, sub-tropical and Mediterranean areas a
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-12
This book explores the intricate world of livestock sciences and production through the lens of systems biology. Offering a comprehensive exploration of both fundamental and advanced aspects, it unearths the potential of systems biology in the realm
Autor:
Sandeep Swargam, Raghvendra Kulkarni, Sumangala Patil, Prachi P Parvatikar, Joy Hoskeri, Kusal K Das
Publikováno v:
Current computer-aided drug design. 18(1)
Aim: This study aimed at screening and development of TG2 inhibitors as anti lung cancer agent. Background: Transglutaminase 2 (TG2) is multifunctional and ubiquitously expressed protein from the transglutaminase family. It takes part in various cell
Autor:
Umamaheswari Amineni, Munikumar Manne, Sandeep Swargam, Vengamma Bhuma, Pradeep Natarajan, Vani Priyadarshini, Hema Kanipakam, Dibyabhaba Pradhan
Publikováno v:
Journal of Receptors and Signal Transduction. 36:445-458
Glycogen synthase kinase-3β (GSK-3β) is a serine/threonine kinase which has attracted significant attention during recent years in drug design studies. The deregulation of GSK-3β increased the loss of hippocampal neurons by triggering apoptosis-me
Autor:
Sandeep Swargam, eep, Amineni Umamaheswari, Pasala Chiranjeevi, Natarajan Pradeep, Kanipakam Hema, Nalamolu Ravina Madhulitha, Katari Sudheer Kumar
Publikováno v:
Biochemistry & Analytical Biochemistry.
The nitric oxide (NO) synthesized by neuronal nitric oxide synthase (nNOS) acts as a neurotransmitter and plays a crucial role in a series of neurobiological functions. In diseased condition, activated nNOS induces nitrosylation as well as phosphoryl
Autor:
Sudheer Kumar Katari, Chiranjeevi Pasala, Sandeep Swargam, Pradeep Natarajan, Amineni Umamaheswari, Hema Kanipakam
Publikováno v:
Journal of receptor and signal transduction research. 36(6)
c-Jun-NH2 terminal kinases (JNKs) come under a class of serine/threonine protein kinases and are encoded by three genes, namely JNK1, JNK2 and JNK3. Human JNK1 is a cytosolic kinase belonging to mitogen-activated protein kinase (MAPK) family, which p
Identification of Putative Drug Targets and Vaccine Candidates for Pathogens Causing Atherosclerosis
Autor:
Kanipakam Hema, Manne Munikumar, Vani Priyadarshini I, eep, Suchitra Mm, Natarajan Pradeep, Amineni Umamaheswari, Dibyabhaba Pradhan, Sandeep Swargam
Publikováno v:
Biochemistry & Analytical Biochemistry.
Atherosclerosis is a chronic inflammatory artery disease, responsible for both cardiovascular (heart) and cerebrovascular (brain) stroke with high morbidity and mortality worldwide. Infectious pathogens such as Chlamydophila pneumoniae, Porphyromonas