Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Sandeep Sheth"'
Autor:
Hemlata Kaurav, Meenakshi Tripathi, Simran Deep Kaur, Amit Bansal, Deepak N. Kapoor, Sandeep Sheth
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 697 (2024)
In recent years, there has been a notable surge in the utilization of stabilized bile acid liposomes, chemical conjugates, complexes, mixed micelles, and other drug delivery systems derived from bile acids, often referred to as bilosomes. The molecul
Externí odkaz:
https://doaj.org/article/dc9f7e085e694df0bed995cf0f0f9eb8
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Carbon dots (CDs), which have particle size of less than 10 nm, are carbon-based nanomaterials that are used in a wide range of applications in the area of novel drug delivery in cancer, ocular diseases, infectious diseases, and brain disorders. CDs
Externí odkaz:
https://doaj.org/article/4a5f3e26a08241e984b3423c881078f2
Autor:
Raheem F. H. Al Aameri, Entkhab M. A. Alanisi, Adu Oluwatosin, Dheyaa Al Sallami, Sandeep Sheth, Ian Alberts, Shree Patel, Leonard P. Rybak, Vickram Ramkumar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cisplatin is chemotherapy used for solid tumor treatment like lung, bladder, head and neck, ovarian and testicular cancers. However, cisplatin-induced ototoxicity limits the utility of this agent in cancer patients, especially when dose escalations a
Externí odkaz:
https://doaj.org/article/e5743741007e48a3a2bb4cfac44969d4
Autor:
Asmita Dhukhwa, Raheem F. H. Al Aameri, Sandeep Sheth, Debashree Mukherjea, Leonard Rybak, Vickram Ramkumar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Regulators of G protein signaling (RGS) accelerate the GTPase activity of G proteins to enable rapid termination of the signals triggered by G protein-coupled receptors (GPCRs). Activation of several GPCRs, including cannabinoid receptor 2 (
Externí odkaz:
https://doaj.org/article/f7bd4bab02fb490bac2efed2eca9e9b6
Targeting Inflammatory Processes Mediated by TRPVI and TNF-α for Treating Noise-Induced Hearing Loss
Autor:
Asmita Dhukhwa, Puspanjali Bhatta, Sandeep Sheth, Krishi Korrapati, Coral Tieu, Chaitanya Mamillapalli, Vickram Ramkumar, Debashree Mukherjea
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Noise trauma is the most common cause of hearing loss in adults. There are no known FDA approved drugs for prevention or rescue of noise-induced hearing loss (NIHL). In this study, we provide evidence that implicates stress signaling molecules (TRPV1
Externí odkaz:
https://doaj.org/article/7e71ab38c76a4dbdb7ab28bf0757b6ef
Autor:
Sumana Ghosh, Sandeep Sheth, Kelly Sheehan, Debashree Mukherjea, Asmita Dhukhwa, Vikrant Borse, Leonard P. Rybak, Vickram Ramkumar
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells a
Externí odkaz:
https://doaj.org/article/eaafcb60df7f48dcb4f8ce600aeb7ae1
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Evidence of significant hearing loss during the early days of use of cisplatin as a chemotherapeutic agent in cancer patients has stimulated research into the causes and treatment of this side effect. It has generally been accepted that hearing loss
Externí odkaz:
https://doaj.org/article/445b22c5bba74847871fc73444420e12
Autor:
Raheem F H Al Aameri, Sandeep Sheth, Entkhab M A Alanisi, Vikrant Borse, Debashree Mukherjea, Leonard P Rybak, Vickram Ramkumar
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177198 (2017)
Prostate cancer (PCa) is the second leading cause of cancer deaths in men. A better understanding of the molecular basis of prostate cancer proliferation and metastasis should enable development of more effective treatments. In this study we focused
Externí odkaz:
https://doaj.org/article/b830c7f1b75e48f7a04786a94b670d03
Publikováno v:
Cells, Vol 3, Iss 2, Pp 517-545 (2014)
Transient receptor potential vanilloid 1 (TRPV1) is an ion channel present on sensory neurons which is activated by heat, protons, capsaicin and a variety of endogenous lipids termed endovanilloids. As such, TRPV1 serves as a multimodal sensor of nox
Externí odkaz:
https://doaj.org/article/bebff2a94acd4aaba3650161e0e046a0
Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway.
Autor:
Sandeep Sheth, Sarvesh Jajoo, Tejbeer Kaur, Debashree Mukherjea, Kelly Sheehan, Leonard P Rybak, Vickram Ramkumar
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51655 (2012)
The consumption of foods containing resveratrol produces significant health benefits. Resveratrol inhibits cancer by reducing cell proliferation and metastasis and by inducing apoptosis. These actions could be explained by its ability to inhibit (ERK
Externí odkaz:
https://doaj.org/article/e983ef1192294323b9b9287310f67af8