Sensitivity of an AI method for [18F]FDG PET/CT outcome prediction of diffuse large B-cell lymphoma patients to image reconstruction protocols

Autor: Maria C. Ferrández, Sandeep S. V. Golla, Jakoba J. Eertink, Bart M. de Vries, Sanne E. Wiegers, Gerben J. C. Zwezerijnen, Simone Pieplenbosch, Louise Schilder, Martijn W. Heymans, Josée M. Zijlstra, Ronald Boellaard

Publikováno v: EJNMMI Research, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract Background Convolutional neural networks (CNNs), applied to baseline [18F]-FDG PET/CT maximum intensity projections (MIPs), show potential for treatment outcome prediction in diffuse large B-cell lymphoma (DLBCL). The aim of this study is to

Externí odkaz: https://doaj.org/article/cbda86c527ec46e18d80e8f0c03767b8

Altered brain metabolism in frontotemporal dementia and psychiatric disorders: involvement of the anterior cingulate cortex

Autor: Marie-Paule E. van Engelen, Sander C. J. Verfaillie, Annemieke Dols, Mardien L. Oudega, Ronald Boellaard, Sandeep S. V. Golla, Marijke den Hollander, Rik Ossenkoppele, Philip Scheltens, Bart N. M. van Berckel, Yolande A. L. Pijnenburg, Everard G. B. Vijverberg

Publikováno v: EJNMMI Research, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract Background Behavioural symptoms and frontotemporal hypometabolism overlap between behavioural variant of frontotemporal dementia (bvFTD) and primary psychiatric disorders (PPD), hampering diagnostic distinction. Voxel-wise comparisons of bra

Externí odkaz: https://doaj.org/article/2e33ccec1e054043a8dbf5dff021fd33

Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET

Autor: Hayel Tuncel, Ronald Boellaard, Emma M. Coomans, Marijke den Hollander-Meeuwsen, Erik F. J. de Vries, Andor W. J. M. Glaudemans, Paula Kopschina Feltes, David Vállez García, Sander C. J. Verfaillie, Emma E. Wolters, Steven P. Sweeney, J. Michael Ryan, Magnus Ivarsson, Berkley A. Lynch, Patrick Schober, Philip Scheltens, Robert C. Schuit, Albert D. Windhorst, Peter P. De Deyn, Bart N. M. van Berckel, Sandeep S. V. Golla

Publikováno v: EJNMMI Research, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract [11C]UCB-J is a PET radioligand that binds to the presynaptic vesicle glycoprotein 2A. Therefore, [11C]UCB-J PET may serve as an in vivo marker of synaptic integrity. The main objective of this study was to evaluate the quantitative accuracy

Externí odkaz: https://doaj.org/article/1d98093e987342dd9416579091feee0d

Tau pathology as determinant of changes in atrophy and cerebral blood flow

Autor: Denise Visser, Sander C. J. Verfaillie, Iris Bosch, Iman Brouwer, Hayel Tuncel, Emma M. Coomans, Roos M. Rikken, Sophie E. Mastenbroek, Sandeep S. V. Golla, Frederik Barkhof, Elsmarieke van de Giessen, Bart N. M. van Berckel, Wiesje M. van der Flier, Rik Ossenkoppele

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging, 50(8), 2409-2419. Springer Verlag
Visser, D, Verfaillie, S C J, Bosch, I, Brouwer, I, Tuncel, H, Coomans, E M, Rikken, R M, Mastenbroek, S E, Golla, S S V, Barkhof, F, van de Giessen, E, van Berckel, B N M, van der Flier, W M & Ossenkoppele, R 2023, ' Tau pathology as determinant of changes in atrophy and cerebral blood flow : a multi-modal longitudinal imaging study ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 50, no. 8, pp. 2409-2419 . https://doi.org/10.1007/s00259-023-06196-2

Purpose Tau pathology is associated with concurrent atrophy and decreased cerebral blood flow (CBF) in Alzheimer’s disease (AD), but less is known about their temporal relationships. Our aim was therefore to investigate the association of concurren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59aaf4513d266a4438b0d9a124af4e9
https://doi.org/10.1007/s00259-023-06196-2

3D Convolutional Neural Network-Based Denoising of Low-Count Whole-Body 18F-Fluorodeoxyglucose and 89Zr-Rituximab PET Scans

Autor: Bart M. de Vries, Sandeep S. V. Golla, Gerben J. C. Zwezerijnen, Otto S. Hoekstra, Yvonne W. S. Jauw, Marc C. Huisman, Guus A. M. S. van Dongen, Willemien C. Menke-van der Houven van Oordt, Josée J. M. Zijlstra-Baalbergen, Liesbet Mesotten, Ronald Boellaard, Maqsood Yaqub

Publikováno v: Diagnostics, Vol 12, Iss 3, p 596 (2022)

Acquisition time and injected activity of 18F-fluorodeoxyglucose (18F-FDG) PET should ideally be reduced. However, this decreases the signal-to-noise ratio (SNR), which impairs the diagnostic value of these PET scans. In addition, 89Zr-antibody PET i

Externí odkaz: https://doaj.org/article/a126295b2b554a6f80b62a95d68b22e0