Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sandeep R.P. Kumar"'
B cell focused transient immune suppression protocol for efficient AAV readministration to the liver
Autor:
Jyoti Rana, Roland W. Herzog, Maite Muñoz-Melero, Kentaro Yamada, Sandeep R.P. Kumar, Anh K. Lam, David M. Markusic, Dongsheng Duan, Cox Terhorst, Barry J. Byrne, Manuela Corti, Moanaro Biswas
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101216- (2024)
Adeno-associated virus (AAV) vectors are used for correcting multiple genetic disorders. Although the goal is to achieve lifelong correction with a single vector administration, the ability to redose would enable the extension of therapy in cases in
Externí odkaz:
https://doaj.org/article/dbfee83096ee41878357669ddf1b4522
Autor:
Sandeep R.P. Kumar, Jun Xie, Shilang Hu, Jihye Ko, Qifeng Huang, Harrison C. Brown, Alok Srivastava, David M. Markusic, Christopher B. Doering, H. Trent Spencer, Arun Srivastava, Guangping Gao, Roland W. Herzog
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 98-107 (2021)
Hepatic gene transfer with adeno-associated viral (AAV) vectors shows much promise for the treatment of the X-linked bleeding disorder hemophilia B in multiple clinical trials. In an effort to further innovate this approach and to introduce alternati
Externí odkaz:
https://doaj.org/article/c8c0531282d4473082e53448b9e6d260
Autor:
Moanaro Biswas, Damien Marsic, Ning Li, Chenhui Zou, Gloria Gonzalez-Aseguinolaza, Irene Zolotukhin, Sandeep R.P. Kumar, Jyoti Rana, John S.S. Butterfield, Oleksandr Kondratov, Ype P. de Jong, Roland W. Herzog, Sergei Zolotukhin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 347-361 (2020)
Limitations to successful gene therapy with adeno-associated virus (AAV) can comprise pre-existing neutralizing antibodies to the vector capsid that can block cellular entry, or inefficient transduction of target cells that can lead to sub-optimal ex
Externí odkaz:
https://doaj.org/article/05f6a412488548bf8d9ee4437f4100f3
Autor:
Xiaomei Wang, Roland W. Herzog, Barry J. Byrne, Sandeep R.P. Kumar, Qi Zhou, Christian J. Buchholz, Moanaro Biswas
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 76-82 (2017)
Gene-modified B cells expressing immunoglobulin G (IgG) fusion proteins have been shown to induce tolerance in several autoimmune and other disease models. However, lack of a vector suitable for gene transfer to human B cells has been an obstacle for
Externí odkaz:
https://doaj.org/article/cbfc10cca4284189aca738ec77b936ec
Autor:
Rajeev Mehla, Sandeep R.P. Kumar, Pragya D. Yadav, Pradip V. Barde, Prasanna N. Yergolkar, Bobbie R. Erickson, Serena A. Carroll, Akhilesh C. Mishra, Stuart T. Nichol, Devendra T. Mourya
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 9, Pp 1431-1437 (2009)
Kyasanur Forest disease virus (KFDV) is enzootic to India and maintained in ticks, mammals, and birds. It causes severe febrile illness in humans and was first recognized in 1957 associated with a high number of deaths among monkeys in Kyasanur Fores
Externí odkaz:
https://doaj.org/article/68a81e30511b42e39b332c769f1de194
Publikováno v:
Human Gene Therapy. 34:365-371
Autor:
John S.S. Butterfield, Kentaro Yamada, Thais B. Bertolini, Farooq Syed, Sandeep R.P. Kumar, Xin Li, Sreevani Arisa, Annie R. Piñeros, Alejandro Tapia, Christopher A. Rogers, Ning Li, Jyoti Rana, Moanaro Biswas, Cox Terhorst, Randal J. Kaufman, Ype P. de Jong, Roland W. Herzog
Publikováno v:
Molecular Therapy. 30:3552-3569
Autor:
Moanaro Biswas, Thais Bertolini, Kaman So, Jyoti Rana, Sandeep R.P. Kumar, Sha Cao, Hongyu Gao, Xiaoling Xuei, Henry Daniell, Roland W. Herzog
Publikováno v:
Blood. 140:11273-11274
Publikováno v:
Blood. 140:4928-4929
Autor:
Thais B. Bertolini, Roland W. Herzog, Sandeep R.P. Kumar, Alexandra Sherman, Jyoti Rana, Radoslaw Kaczmarek, Kentaro Yamada, Sreevani Arisa, David Lillicrap, Cox Terhorst, Henry Daniell, Moanaro Biswas
Publikováno v:
Cellular Immunology. 385:104675