Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sandeep Pallerla"'
Autor:
Rushikesh Sable, Nithya Jambunathan, Sitanshu Singh, Sandeep Pallerla, Konstantin G Kousoulas, Seetharama Jois
Publikováno v:
BioTechniques, Vol 65, Iss 3, Pp 149-157 (2018)
Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently
Externí odkaz:
https://doaj.org/article/3ed450dac3884a9993c31e64ffbd547e
Autor:
Seetharama D. Jois, Sitanshu S. Singh, Nithya Jambunathan, Rushikesh Sable, Konstantin G. Kousoulas, Sandeep Pallerla
Publikováno v:
Biotechniques
Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d648ef6ab04767e6217cd60af1ab7b
http://europepmc.org/articles/PMC6770473
http://europepmc.org/articles/PMC6770473
Autor:
Sami Nazzal, Sandeep Pallerla, Sara Shakhwar, Rana Darwish, Ahmed Abu Fayyad, Mohammad M. Kamal
Publikováno v:
Pharmaceutical development and technology. 25(4)
Tocosol™ is a tocopherol-based paclitaxel (PTX) nanoemulsion consisting of α-tocopherol (α-T) isomer of vitamin E as a solubilizer and vitamin E TPGS as the primary emulsifier. Despite its positive attributes in early clinical studies, it failed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338387b8e6b69ada09b6e7e6b4cf6c46
https://pubmed.ncbi.nlm.nih.gov/31858867
https://pubmed.ncbi.nlm.nih.gov/31858867
Autor:
Shanthi Kanthala, Seetharama D. Jois, Sandeep Pallerla, Rushikesh Sable, Yong-Yu Liu, Sitanshu S. Singh
Publikováno v:
Oncotarget
// Shanthi P. Kanthala 1 , Yong-Yu Liu 1 , Sitanshu Singh 1 , Rushikesh Sable 1 , Sandeep Pallerla 1 and Seetharama D. Jois 1 1 Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe LA 71201, USA Correspondence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156d86bfb02b033403c89313fbbb6b4c
https://doi.org/10.18632/oncotarget.19013
https://doi.org/10.18632/oncotarget.19013
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 779, p 779 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Breast cancer is one of the leading causes of death in women. With improvements in early-stage diagnosis and targeted therapies, there has been an improvement in the overall survival rate in breast cancer over the past decade. Despite the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e464d957aa8d12f734221bfc425f3981
https://doi.org/10.3390/ijms22020779
https://doi.org/10.3390/ijms22020779
Autor:
Thomas Durek, Seetharama D. Jois, David J. Craik, Ted J. Gauthier, Sandeep Pallerla, Veena Taneja, Rushikesh Sable
Publikováno v:
ACS Chemical Biology. 11:2366-2374
The interaction between the cell-cell adhesion proteins CD2 and CD58 plays a crucial role in lymphocyte recruitment to inflammatory sites, and inhibitors of this interaction have potential as immunomodulatory drugs in autoimmune diseases. Peptides fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318d18f084c625e3b2f47a4e0de2658b
https://doi.org/10.1021/acschembio.6b00486
https://doi.org/10.1021/acschembio.6b00486
Publikováno v:
Future Oncology. 11:865-878
ABSTRACT Expression of the EGF receptors (EGFRs) is abnormally high in many types of cancer, including 25% of lung cancers. Successful treatments target mutations in the EGFR tyrosine kinase domain with EGFR tyrosine kinase inhibitors (TKIs). However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fa3f99529ce2d7737548fac4e81b93
https://doi.org/10.2217/fon.14.312
https://doi.org/10.2217/fon.14.312
Autor:
Ted J. Gauthier, Sitanshu S. Singh, Himgauri Naik, Rushikesh Sable, Seetharama D. Jois, Sandeep Pallerla
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 24(2)
HER2 receptors are surface proteins belonging to the epidermal growth factor family of receptors. Their numbers are elevated in breast, lung, and ovarian cancers. HER2-positive cancers are aggressive, have higher mortality rate, and have a poor progn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fcd645f2e74b6f3a36920612adc3db
https://pubmed.ncbi.nlm.nih.gov/29436155
https://pubmed.ncbi.nlm.nih.gov/29436155
Publikováno v:
European journal of medicinal chemistry. 125
Doxorubicin (DOX) belongs to the anthracycline class of drugs that are used in the treatment of various cancers. It has limited cystostatic effects in therapeutic doses, but higher doses can cause cardiotoxicity. In the current approach, we conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c644f294612dbd1fee9b9cbf39c4931
https://pubmed.ncbi.nlm.nih.gov/27769032
https://pubmed.ncbi.nlm.nih.gov/27769032