Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sandeep P. Dave"'
Autor:
Dashnamoorthy Ravi, Afshin Beheshti, Nasséra Abermil, Frederick Lansigan, William Kinlaw, Nirupa R. Matthan, Maisarah Mokhtar, Frank C. Passero, Patrick Puliti, Kevin A. David, Gregory G. Dolnikowski, Xiaoyang Su, Ying Chen, Mahboubi Bijan, Rohan R. Varshney, Baek Kim, Sandeep S. Dave, Michael C. Rudolph, Andrew M. Evens
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Metabolic dysfunctions enabling increased nucleotide biosynthesis are necessary for supporting malignant proliferation. Our investigations indicate that upregulation of fatty acid synthase (FASN) and de novo lipogenesis, commonly observed in many can
Externí odkaz:
https://doaj.org/article/f972557711444ad6a3fe53f5e725b9dd
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Our understanding of the genetics and treatment options for primary effusion lymphoma (PEL) is lacking. Here the authors performed in vitro CRISPR/Cas9 knock-out screens to identify 210 PEL-specific oncogenic genes and report strategies for therapeut
Externí odkaz:
https://doaj.org/article/4753b6af0a0c4636a623f9ba180cea46
Autor:
Jianguo Huang, Mark Chen, Melodi Javid Whitley, Hsuan-Cheng Kuo, Eric S. Xu, Andrea Walens, Yvonne M. Mowery, David Van Mater, William C. Eward, Diana M. Cardona, Lixia Luo, Yan Ma, Omar M. Lopez, Christopher E. Nelson, Jacqueline N. Robinson-Hamm, Anupama Reddy, Sandeep S. Dave, Charles A. Gersbach, Rebecca D. Dodd, David G. Kirsch
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Site-specific recombination and CRISPR-Cas9 have been used to generate genetically engineered mouse models of cancer. Here the authors compare sarcomas generated using both systems and see similar genetic and cellular phenotypes, suggesting CRISPR-Ca
Externí odkaz:
https://doaj.org/article/43b8c0058e5a4216b4fb7dadf1a3b419
Autor:
Dora Posfai, Kayla Sylvester, Anupama Reddy, Jack G Ganley, Johannes Wirth, Quinlan E Cullen, Tushar Dave, Nobutaka Kato, Sandeep S Dave, Emily R Derbyshire
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007057 (2018)
Within the liver a single Plasmodium parasite transforms into thousands of blood-infective forms to cause malaria. Here, we use RNA-sequencing to identify host genes that are upregulated upon Plasmodium berghei infection of hepatocytes with the hypot
Externí odkaz:
https://doaj.org/article/5afc4dbb8588431aaa25768808694a9a
Autor:
Sumedha Roy, Amanda J. Moore, Cassandra Love, Anupama Reddy, Deepthi Rajagopalan, Sandeep S. Dave, Leping Li, Cornelis Murre, Yuan Zhuang
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
A family of transcription factors known as E proteins, and their antagonists, Id proteins, regulate T cell differentiation at critical developmental checkpoints. Id proteins promote the differentiation of conventional αβ T cells and suppress the ex
Externí odkaz:
https://doaj.org/article/bd7c443808564641a3bbc5923eb0e58a
Autor:
Lisa Grossman, Chris Chang, Joanne Dai, Pavel A. Nikitin, Dereje D. Jima, Sandeep S. Dave, Micah A. Luftig
Publikováno v:
mSphere, Vol 2, Iss 6 (2017)
ABSTRACT Epstein-Barr virus (EBV), an oncogenic herpesvirus, infects and transforms primary B cells into immortal lymphoblastoid cell lines (LCLs), providing a model for EBV-mediated tumorigenesis. EBV transformation stimulates robust homotypic aggre
Externí odkaz:
https://doaj.org/article/8781b480d55c41a78647de24435d873a
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44362 (2012)
Systemic lupus erythematosus (SLE) is a generalized autoimmune disease characterized by abnormal B cell activation and the occurrence of increased frequencies of circulating plasma cells (PC). The molecular characteristics and nature of circulating P
Externí odkaz:
https://doaj.org/article/4c34957bcfd541a29d81b0619df5a015
Autor:
Itziar Salaverria, Andreas Zettl, Silvia Beà, Elena M. Hartmann, Sandeep S. Dave, George W. Wright, Evert-Jan Boerma, Philip M. Kluin, German Ott, Wing C. Chan, Dennis D. Weisenburger, Armando Lopez-Guillermo, Randy D. Gascoyne, Jan Delabie, Lisa M. Rimsza, Rita M. Braziel, Elaine S. Jaffe, Louis M. Staudt, Hans Konrad Müller-Hermelink, Elias Campo, Andreas Rosenwald, for the Leukemia and Lymphoma Molecular Profiling Project (LLMPP)
Publikováno v:
Haematologica, Vol 93, Iss 9 (2008)
Background Burkitt’s lymphoma is an aggressive B-cell lymphoma characterized by typical morphological, immunophenotypic and molecular features. Gene expression profiling provided a molecular signature of Burkitt’s lymphoma, but also demonstrated
Externí odkaz:
https://doaj.org/article/a7ad9019fd2f423a83fb8ff086cb34f3
Publikováno v:
Otolaryngology–Head and Neck Surgery. 136:920-927
Objective To report the surgical outcomes and safety of transnasal endoscopic resection (TER) for anterior skull base (ASB) tumors. Study Design and Setting A retrospective chart review to identify patients undergoing TER for ASB tumors at a tertiary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68938d8097bc7c1f7b098fdae5ef62e0
https://doi.org/10.1016/j.otohns.2007.01.012
https://doi.org/10.1016/j.otohns.2007.01.012
Publikováno v:
Acta Oto-Laryngologica. 127:280-284
We present the third case of mucoepidermoid carcinoma of the external auditory canal (EAC) in the English literature, and discuss the management of this lesion. The patient underwent a wide local resection, superficial parotidectomy, and selective ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42f499c38b3a72092eb87ae183381c4
https://doi.org/10.1080/00016480600818120
https://doi.org/10.1080/00016480600818120