Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sandeep Nadella"'
Autor:
Dane A. Thompson, Tea Tsaava, Arvind Rishi, Sandeep Nadella, Lopa Mishra, David A. Tuveson, Valentin A. Pavlov, Michael Brines, Kevin J. Tracey, Sangeeta S. Chavan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInflammation is an inherently self-amplifying process, resulting in progressive tissue damage when unresolved. A brake on this positive feedback system is provided by the nervous system which has evolved to detect inflammatory signals and
Externí odkaz:
https://doaj.org/article/53f01de90ba54c5f84c8e02d0440fff9
Autor:
Julian Burks, Sandeep Nadella, Abdullah Mahmud, Charoen Mankongpaisarnrung, Juan Wang, Jong-In Hahm, Robin D. Tucker, Narayan Shivapurkar, Stephan T. Stern, Jill P. Smith
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 1, Pp 17-32 (2018)
Pancreatic ductal adenocarcinoma (PDAC) remains the most aggressive malignancy with the lowest 5-year survival rate of all cancers in part owing to the lack of tumor-specific therapy and the rapid metastatic nature of this cancer. The gastrointestina
Externí odkaz:
https://doaj.org/article/2b74bdbfe6f94384abdd7ecb6ed5e1b1
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 75-83 (2017)
Gastric cancer is the third leading cause of cancer-related mortality worldwide. Despite progress in understanding its development, challenges with treatment remain. Gastrin, a peptide hormone, is trophic for normal gastrointestinal epithelium. G
Externí odkaz:
https://doaj.org/article/47c6e10e47ec41f691c25891b65b17b7
Autor:
Sandeep Nadella, Jill Smith, Julian Burks, Abdulhameed Al-Sabban, Juan Wang, Robin Tucker, Gloria Inyang
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 60-61 (2017)
OBJECTIVES/SPECIFIC AIMS: Epidemiologic studies have found that the incidence of pancreatic cancer is greatest in countries that consume diets high in fat. The gastrointestinal peptide cholecystokinin (CCK) is released from the duodenum in response t
Externí odkaz:
https://doaj.org/article/3fd7b4300fa8404d90e672c35b1ea471
Publikováno v:
Journal of Open Innovation: Technology, Market and Complexity, Vol 10, Iss 3, Pp 100351- (2024)
Many educators across U.S. high schools face information quality and system quality challenges when using learning management systems (LMS). These challenges impact both the individual and organizational levels, affecting overall success. The purpose
Externí odkaz:
https://doaj.org/article/6fa50aca5cfe48c2a0e7fc06edb40f46
Autor:
Atoosa Rabiee, Martha D. Gay, Narayan Shivapurkar, Hong Cao, Sandeep Nadella, Coleman I. Smith, James H. Lewis, Sunil Bansal, Amrita Cheema, John Kwagyan, Jill P. Smith
Publikováno v:
Clinical pharmacology and therapeutics. 112(6)
High saturated fat diets have been shown to raise blood levels of cholecystokinin (CCK) and induce nonalcoholic steatohepatitis (NASH). CCK receptors are expressed on stellate cells and are responsible for hepatic fibrosis when activated. The purpose
Publikováno v:
World Journal of Hepatology
Background Direct-acting antiviral (DAA) therapy regimens are highly effective at eliminating hepatitis C virus (HCV) infection but rates of sustained virologic response (SVR) are lower in patients with decompensated cirrhosis or hepatocellular carci
Autor:
Christina M Brennan, Sandeep Nadella, Xiang Zhao, Richard J Dima, Nicole Jordan-Martin, Breanna R Demestichas, Sam O Kleeman, Miriam Ferrer, Eva Carlotta von Gablenz, Nicholas Mourikis, Michael E Rubin, Harsha Adnani, Hassal Lee, Taehoon Ha, Soma Prum, Cheryl B Schleicher, Sharon S Fox, Michael G Ryan, Christina Pili, Gary Goldberg, James M Crawford, Sara Goodwin, Xiaoyue Zhang, Jonathan B Preall, Ana S H Costa, Joseph Conigliaro, Joseph R Masci, Jie Yang, David A Tuveson, Kevin J Tracey, Tobias Janowitz
Publikováno v:
Gut. 71(5)
ObjectiveWe assessed whether famotidine improved inflammation and symptomatic recovery in outpatients with mild to moderate COVID-19.DesignRandomised, double-blind, placebo-controlled, fully remote, phase 2 clinical trial (NCT04724720) enrolling symp
Autor:
Sandeep Nadella, John G. Lieb
Publikováno v:
Pancreas
OBJECTIVES: The objective was to assess if the peak bicarbonate level during secretin stimulation testing (SST) differs between patients with minimal change (or small duct) chronic pancreatitis (CP) vs those with obvious CP (or large duct) vs those w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5330d8a9ac8f945c0e9dc6b7c8434ced
https://europepmc.org/articles/PMC8887794/
https://europepmc.org/articles/PMC8887794/
Dual-Action Ru(II) Complexes with Bulky π-Expansive Ligands: Phototoxicity without DNA Intercalation
Publikováno v:
Inorg Chem
We report the synthesis and photochemical and biological characterization of Ru(II) complexes containing π-expansive ligands derived from dimethylbenzo[i]dipyrido[3,2-a:2′,3′-c]phenazine (Me(2)dppn) adorned with flanking aryl substituents. Late-