Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Sandeep Nadella"'
Publikováno v:
Journal of Open Innovation: Technology, Market and Complexity, Vol 10, Iss 3, Pp 100351- (2024)
Many educators across U.S. high schools face information quality and system quality challenges when using learning management systems (LMS). These challenges impact both the individual and organizational levels, affecting overall success. The purpose
Externí odkaz:
https://doaj.org/article/6fa50aca5cfe48c2a0e7fc06edb40f46
Autor:
Dane A. Thompson, Tea Tsaava, Arvind Rishi, Sandeep Nadella, Lopa Mishra, David A. Tuveson, Valentin A. Pavlov, Michael Brines, Kevin J. Tracey, Sangeeta S. Chavan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInflammation is an inherently self-amplifying process, resulting in progressive tissue damage when unresolved. A brake on this positive feedback system is provided by the nervous system which has evolved to detect inflammatory signals and
Externí odkaz:
https://doaj.org/article/53f01de90ba54c5f84c8e02d0440fff9
Autor:
Julian Burks, Sandeep Nadella, Abdullah Mahmud, Charoen Mankongpaisarnrung, Juan Wang, Jong-In Hahm, Robin D. Tucker, Narayan Shivapurkar, Stephan T. Stern, Jill P. Smith
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 1, Pp 17-32 (2018)
Pancreatic ductal adenocarcinoma (PDAC) remains the most aggressive malignancy with the lowest 5-year survival rate of all cancers in part owing to the lack of tumor-specific therapy and the rapid metastatic nature of this cancer. The gastrointestina
Externí odkaz:
https://doaj.org/article/2b74bdbfe6f94384abdd7ecb6ed5e1b1
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 75-83 (2017)
Gastric cancer is the third leading cause of cancer-related mortality worldwide. Despite progress in understanding its development, challenges with treatment remain. Gastrin, a peptide hormone, is trophic for normal gastrointestinal epithelium. G
Externí odkaz:
https://doaj.org/article/47c6e10e47ec41f691c25891b65b17b7
Autor:
Giuseppina Caligiuri, Jennifer S. Thalappillil, Mojdeh Shakiba, Sandeep Nadella, Juliene Hinds, Elise Courtois, William F. Flynn, Brinda Alagesan, Georgi N. Yordanov, Benjamin Kaminow, Paul Robson, Pedro A. Perez-Mancera, Jonathan Preall, Alexander Dobin, Youngku Park, David A. Tuveson
Publikováno v:
Cancer Research. 82:C084-C084
The complexity of the tumor microenvironment (TME) is one of the distinguishing features of pancreatic ductal adenocarcinoma (PDA) and is responsible for patients’ poor response to therapies. The heterogeneity of cancer-associated fibroblasts (CAFs
Autor:
Hassal Lee, Alexander Shakeel Bates, Richard Dima, Sandeep Nadella, Nicole Jordan-Martin, Christina Brennan, Tobias Janowitz
Publikováno v:
Cancer Research. 82:A050-A050
The current under-representation of racial and ethnic minorities and socio-economically disadvantaged participants in clinical trials represents an important problem, because it reduces generalizability of trial results and should urgently be address
Autor:
Atoosa Rabiee, Martha D. Gay, Narayan Shivapurkar, Hong Cao, Sandeep Nadella, Coleman I. Smith, James H. Lewis, Sunil Bansal, Amrita Cheema, John Kwagyan, Jill P. Smith
Publikováno v:
Clinical pharmacology and therapeutics. 112(6)
High saturated fat diets have been shown to raise blood levels of cholecystokinin (CCK) and induce nonalcoholic steatohepatitis (NASH). CCK receptors are expressed on stellate cells and are responsible for hepatic fibrosis when activated. The purpose
Publikováno v:
World Journal of Hepatology
Background Direct-acting antiviral (DAA) therapy regimens are highly effective at eliminating hepatitis C virus (HCV) infection but rates of sustained virologic response (SVR) are lower in patients with decompensated cirrhosis or hepatocellular carci
Autor:
Jennifer S. Thalappillil, Giuseppina Caligiuri, Sandeep Nadella, Brinda Alagesan, Georgi N. Yordanov, Mojdeh Shakiba, Benjamin Kaminow, Juliene Hinds, Pedro A. Perez-Mancera, Jonathan Preall, Alexander Dobin, Youngkyu Park, David A. Tuveson
Publikováno v:
Cancer Research. 82:3647-3647
Pancreatic ductal adenocarcinoma (PDAC) is currently the third-leading cause of cancer-related deaths in the United States with no effective or targeted therapies to improve outcomes. Two defining features of PDAC are the dense stroma composing the b
Dual-Action Ru(II) Complexes with Bulky π-Expansive Ligands: Phototoxicity without DNA Intercalation
Publikováno v:
Inorg Chem
We report the synthesis and photochemical and biological characterization of Ru(II) complexes containing π-expansive ligands derived from dimethylbenzo[i]dipyrido[3,2-a:2′,3′-c]phenazine (Me(2)dppn) adorned with flanking aryl substituents. Late-