Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sandeep Kumar Barodia"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14421 (2023)
Neurodegeneration is an age-dependent progressive phenomenon with no defined cause. Aging is the main risk factor for neurodegenerative diseases. During aging, activated microglia undergo phenotypic alterations that can lead to neuroinflammation, whi
Externí odkaz:
https://doaj.org/article/5765cb04cb1243faadba8bc15d83517e
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Externí odkaz:
https://doaj.org/article/c3d30eb8e46f4346bd49292f6a9f5379
Autor:
Carolina Francelin, Sayak K. Mitter, Qingwen Qian, Sandeep Kumar Barodia, Colin Ip, Xiaoping Qi, Hongmei Gu, Judith Quigley, Matthew S. Goldberg, Maria B. Grant, Michael E. Boulton
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1539 (2021)
BACE1 is a key enzyme facilitating the generation of neurotoxic β-amyloid (Aβ) peptide. However, given that BACE1 has multiple substrates we explored the importance of BACE1 in the maintenance of retinal pigment epithelial (RPE) cell homeostasis un
Externí odkaz:
https://doaj.org/article/8896f84f75754c2aada8ef98e76f128e
Publikováno v:
Biochimica et biophysica acta. General subjects. 1866(12)
Stimulation of Asub2A/subreceptors (Asub2A/subR) coupled to Gsubs/sub/olf protein activates Adenylyl cyclase (AC) leading to the release of cAMP which activates the cAMP-dependent PKA phosphorylation. The possible role of Asub2A/subR in the modulatio
Autor:
Xu Hou, Fabienne C. Fiesel, Jens O. Watzlawik, Michael G. Heckman, Wolfdieter Springer, Owen A. Ross, Matthew S. Goldberg, Zbigniew K. Wszolek, Michael DeTure, Sandeep Kumar Barodia, Dennis W. Dickson, Joanna Siuda, Chloe Ramnarine, Tania F. Gendron, Guojun Bu, Dominika Fricova, Clemens R. Scherzer
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Mitochondrial dysfunction is an early, imminent event in neurodegenerative disorders including Parkinson disease (PD) and Alzheimer disease (AD). The enzymatic pair PINK1 and PRKN/Parkin recognize and transiently label damaged mitochondria with ubiqu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1866:130242
Publikováno v:
Frontiers Research Topics ISBN: 9782889633340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d7d21039fa12164d8ee671a93a38004
https://doi.org/10.3389/978-2-88963-334-0
https://doi.org/10.3389/978-2-88963-334-0
Autor:
Sandeep Kumar Barodia, Elijah K Quinones, Rita M. Cowell, Laura J. McMeekin, Rose B. Creed, Matthew S. Goldberg
Publikováno v:
NPJ Parkinson's Disease
npj Parkinson's Disease, Vol 5, Iss 1, Pp 1-9 (2019)
npj Parkinson's Disease, Vol 5, Iss 1, Pp 1-9 (2019)
Loss-of-function mutations in PINK1 are causally linked to recessively inherited Parkinson’s disease (PD), with marked loss of dopaminergic neurons in the substantia nigra that are required for normal movement. PINK1 is a nuclear-encoded mitochondr
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience, Vol 13 (2019)
Autor:
Maria B. Grant, Sayak K. Mitter, Xiaoping Qi, Sandeep Kumar Barodia, Judith Quigley, Michael E. Boulton, Carolina Francelin, Hongmei Gu, Colin S. Ip, Qingwen Qian, Matthew S. Goldberg
Publikováno v:
Antioxidants
Volume 10
Issue 10
Antioxidants, Vol 10, Iss 1539, p 1539 (2021)
Volume 10
Issue 10
Antioxidants, Vol 10, Iss 1539, p 1539 (2021)
BACE1 is a key enzyme facilitating the generation of neurotoxic β-amyloid (Aβ) peptide. However, given that BACE1 has multiple substrates we explored the importance of BACE1 in the maintenance of retinal pigment epithelial (RPE) cell homeostasis un