Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sandeep K. Tripathy"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural killer (NK) cells play an important role in the innate immune response. The summation of activation and inhibitory signals delivered through cell surface membrane receptors determines NK cell function. However, the continuous engagement of an
Externí odkaz:
https://doaj.org/article/f3eddc0cc21649589b986b7a79181d3c
Publikováno v:
ImmunoHorizons. 6(1)
NK cells are important mediators of viral control with the capacity to form adaptive immune features following infection. However, studies of infection-induced adaptive NK cells require adoptive cell transfer to lower the precursor frequency of “Ag
Publikováno v:
The Journal of Immunology. 208:126.07-126.07
NK cells are important mediators of viral control with the capacity to form adaptive immune features following infection. However, studies of infection-induced adaptive NK cells require adoptive cell transfer to lower the precursor frequency of ‘an
Publikováno v:
Immunity, Inflammation and Disease. 5:177-189
Introduction Natural killer (NK) cells play a critical role in the innate immune response to viruses and tumors, and comprise a large proportion of the hepatic lymphocyte population. They must remain tolerant to non-pathogenic antigens while protecti
Autor:
Christina S. Winborn, Thomas S. Griffith, Mikaela M. Tremblay, Christopher M. Snyder, Sandeep K. Tripathy, Qiang Shan, Micaela G. Fosdick, Hai-Hui Xue, Peng Shao, Jon C. D. Houtman, Isaac J. Jensen, Vladimir P. Badovinac
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 10, p e1007405 (2018)
PLoS Pathogens, Vol 14, Iss 10, p e1007405 (2018)
The sepsis-induced cytokine storm leads to severe lymphopenia and reduced effector capacity of remaining/surviving cells. This results in a prolonged state of immunoparalysis, that contributes to enhanced morbidity/mortality of sepsis survivors upon
Autor:
Emily M. Mace, Nermina Saucier, Emily K. Jeng, Hing C. Wong, Sandeep K. Agarwal, Sandeep K. Tripathy, Jeffrey S. Miller, Emily K. Moore, Anthony R. French, Armin Rashidi, Joshua B. Alinger, Annelise Y. Mah, Molly P. Keppel, Megan A. Cooper, Todd A. Fehniger
Publikováno v:
JCI Insight. 2
NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is unknown. We examined the role of glycolysis in NK cell function during murine cytomegalovirus (
Publikováno v:
The Journal of Immunology. 194:1945-1953
Because NK cells secrete cytotoxic granules and cytokines that can destroy surrounding cells and help shape the subsequent immune response, they must be kept under tight control. Several mechanisms, at different levels, are in place to control NK cel
Publikováno v:
European Journal of Immunology. 43:1345-1355
Continuous engagement of the Ly49H activating receptor with its ligand (m157) in a transgenic mouse expressing m157 (m157-Tg) results in hyporesponsiveness of Ly49H(+) NK cells. The same interaction, during murine cytomegalovirus (MCMV) infection, le
Publikováno v:
Immunity, Inflammation and Disease
Introduction Natural killer (NK) cells play a critical role in the innate immune response to viruses and tumors, and comprise a large proportion of the hepatic lymphocyte population. They must remain tolerant to non‐pathogenic antigens while protec
Publikováno v:
Gastroenterology. 152:S1045