Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Sandeep K. Singhal"'
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
PurposeExposure to radiation is a health concern within and beyond the Earth's atmosphere for aircrew and astronauts in their respective austere environments. The biological effects of radiation exposure from a multiomics standpoint are relatively un
Externí odkaz:
https://doaj.org/article/fb081e6c8d5a4987ba2425202f17845c
Autor:
Nathan A. Ruprecht, Sonalika Singhal, Kalli Schaefer, Om Panda, Donald Sens, Sandeep K. Singhal
Publikováno v:
Biology, Vol 13, Iss 2, p 98 (2024)
Multi-omics studies have emerged as powerful tools for tailoring individualized responses to various conditions, capitalizing on genome sequencing technologies’ increasing affordability and efficiency. This paper delves into the potential of multi-
Externí odkaz:
https://doaj.org/article/624aaea2b19f4dfa8f75cfc794c940dd
Autor:
Nathan A. Ruprecht, Sonalika Singhal, Kalli Schaefer, Jappreet S. Gill, Benu Bansal, Donald Sens, Sandeep K. Singhal
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
PurposeOne possible way to quantify each individual's response or damage from ionizing radiation is to estimate their accelerated biological age following exposure. Since there is currently no definitive way to know if biological age estimations are
Externí odkaz:
https://doaj.org/article/5ff5ab4bc5434db4ba1c514b7a1fe222
Autor:
Sandeep K. Singhal, Jung S. Byun, Tingfen Yan, Ryan Yancey, Ambar Caban, Sara Gil Hernandez, Sediqua Bufford, Stephen M. Hewitt, Joy Winfield, Jaya Pradhan, Vesco Mustkov, Jasmine A. McDonald, Eliseo J. Pérez-Stable, Anna María Nápoles, Nasreen Vohra, Adriana De Siervi, Clayton Yates, Melissa B. Davis, Mei Yang, Yien Che Tsai, Allan M. Weissman, Kevin Gardner
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
Women of African ancestry suffer higher rates of breast cancer mortality compared with all other groups in the United States. Though the precise reasons for these disparities remain unclear, many recent studies have implicated a role for differences
Externí odkaz:
https://doaj.org/article/d8136019c67d48819c70238b6e5115e2
Autor:
Md Shakir Uddin Ahmed, Brittany D. Lord, Benjamin Adu Addai, Sandeep K. Singhal, Kevin Gardner, Ahmad Bin Salam, Anghesom Ghebremedhin, Jason White, Iqbal Mahmud, Rachel Martini, Deepa Bedi, Huixian Lin, Jacqueline D. Jones, Balasubramanyanam Karanam, Windy Dean-Colomb, William Grizzle, Honghe Wang, Melissa Davis, Clayton C. Yates
Publikováno v:
Cancers, Vol 15, Iss 8, p 2282 (2023)
African American (AA) women with breast cancer are more likely to have higher inflammation and a stronger overall immune response, which correlate with poorer outcomes. In this report, we applied the nanostring immune panel to identify differences in
Externí odkaz:
https://doaj.org/article/6d7337b62a744d0597bd95df7d61d53d
Autor:
Sonalika Singhal, Scott H. Garrett, Seema Somji, Kalli Schaefer, Benu Bansal, Jappreet Singh Gill, Sandeep K. Singhal, Donald A. Sens
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5092 (2023)
The human kidney is known to possess renal progenitor cells (RPCs) that can assist in the repair of acute tubular injury. The RPCs are sparsely located as single cells throughout the kidney. We recently generated an immortalized human renal progenito
Externí odkaz:
https://doaj.org/article/a986ee0bb43f4497bc03865d5ca3630c
Autor:
Sandeep K. Singhal, Jung S. Byun, Samson Park, Tingfen Yan, Ryan Yancey, Ambar Caban, Sara Gil Hernandez, Stephen M. Hewitt, Heike Boisvert, Stephanie Hennek, Mark Bobrow, Md Shakir Uddin Ahmed, Jason White, Clayton Yates, Andrew Aukerman, Rami Vanguri, Rohan Bareja, Romina Lenci, Paula Lucia Farré, Adriana De Siervi, Anna María Nápoles, Nasreen Vohra, Kevin Gardner
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Through automated image analysis, Singhal et al quantify nuclear versus cytoplasmic distribution of the Kaiso transcription factor in breast cancer patient tissue. They find that Kaiso distribution correlates with breast cancer subtype and overall su
Externí odkaz:
https://doaj.org/article/4e1c6ea4c98943a8a43e8875d77bb47a
Autor:
Sandeep K. Singhal, Sarmad Al-Marsoummi, Emilie E. Vomhof-DeKrey, Bo Lauckner, Trysten Beyer, Marc D. Basson
Publikováno v:
Cancers, Vol 15, Iss 2, p 402 (2023)
The Schlafen 12 (SLFN12) protein regulates triple-negative breast cancer (TNBC) growth, differentiation, and proliferation. SLFN12 mRNA expression strongly correlates with TNBC patient survival. We sought to explore SLFN12 overexpression effects on i
Externí odkaz:
https://doaj.org/article/b4e549ce55234315b3fe98a67df03b16
Autor:
Emilie E. Vomhof-DeKrey, Sonalika Singhal, Sandeep K. Singhal, Allie D. Stover, Odele Rajpathy, Elizabeth Preszler, Luis Garcia, Marc D. Basson
Publikováno v:
Cells, Vol 11, Iss 20, p 3283 (2022)
Background: The intestinal lining renews itself in a programmed fashion that can be affected by adaptation to surgical procedures such as gastric bypass. Methods: To assess adaptive mechanisms in the human intestine after Roux-en-Y gastric bypass (RY
Externí odkaz:
https://doaj.org/article/9b37da8e52c1494d872ef9edf004b2c3
Autor:
Sarmad Al-Marsoummi, Jonathan Pacella, Kaylee Dockter, Matthew Soderberg, Sandeep K. Singhal, Emilie E. Vomhof-DeKrey, Marc D. Basson
Publikováno v:
Cancers, Vol 12, Iss 10, p 2738 (2020)
Schlafen 12 (SLFN12) is an intermediate human Schlafen that induces differentiation in enterocytes, prostate, and breast cancer. We hypothesized that SLFN12 influences lung cancer biology. We investigated survival differences in high versus low SLFN1
Externí odkaz:
https://doaj.org/article/bcbd5c7957b04568a081b50a675179f1