Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Sandeep Dutta"'
Autor:
Janette M. Watkins, Sarah J. Greeven, Kathleen N. Heeter, Julia E. Brunnemer, Jacob Otile, Paola A. Fernández Solá, Sandeep Dutta, James M. Hobson, Justin M. Evanovich, Cassandra J. Coble, Nicole E. Werner, Vanessa M. Martinez Kercher, Kyle A. Kercher
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Purpose The significance of regular physical activity (PA) in reducing cardiovascular disease (CVD) risk is widely acknowledged. However, children in rural areas encounter specific barriers to PA compared to their urban counterparts. This st
Externí odkaz:
https://doaj.org/article/f4c833d7092c47188486d316b7924140
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 1, Pp 154-167 (2024)
Abstract A multistate platform model was developed to describe time‐to‐event (TTE) endpoints in an oncology trial through the following states: initial, tumor response (TR), progressive disease (PD), overall survival (OS) event (death), censor to
Externí odkaz:
https://doaj.org/article/0808f6a0c4ad4836a48f6bc85c6a4925
Autor:
Po‐Wei Chen, Mats O. Karlsson, Sebastian Ueckert, Ari Pritchard‐Bell, Cheng‐Pang Hsu, Sandeep Dutta, Malidi Ahamadi
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 1988-2000 (2023)
Abstract Erenumab is a fully human anti‐canonical calcitonin gene‐related peptide receptor monoclonal antibody approved for migraine prevention. The Migraine‐Specific Quality‐of‐Life Questionnaire (MSQ) is a 14‐item patient‐reported out
Externí odkaz:
https://doaj.org/article/9612d46c23f444d0b99f937a4df1a826
Autor:
Sandeep Dutta, Paola A Fernández Solá, Janette M Watkins, Aidrik Grube, Sarah J Greeven, Cassandra J Coble, Justin M Evanovich, Vanessa M Martinez Kercher, Meredith A Whitley, Kyle A Kercher
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Introduction Cardiovascular disease (CVD) accounts for 18 million deaths per year, disproportionately burdens under-represented racial and ethnic groups, and has economic costs greater than any other health condition. Participation in youth sport may
Externí odkaz:
https://doaj.org/article/05495b9f84774468aa46e7df7d92d428
Autor:
Sarah J. Greeven, Andrew M. Medellin, Janette M. Watkins, Cassandra J. Coble, Julia E. Brunnemer, Paola A. Fernández Solá, Sandeep Dutta, James M. Hobson, Justin M. Evanovich, Vanessa M. Martinez Kercher, Kyle A. Kercher
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionPhysical activity yields significant benefits, yet fewer than 1 in 4 youth meet federal guidelines. Children in rural areas from low socioeconomic (SES) backgrounds face unique physical activity contextual challenges. In line with Stage 0
Externí odkaz:
https://doaj.org/article/6c26e88340ee4ea2abaa7365fe3e0477
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 2, Pp 250-260 (2023)
Abstract Talimogene Laherparepvec (T‐VEC) is a first‐in‐class oncolytic virotherapy approved for the treatment of unresectable melanoma recurrent after initial surgery. Biodistribution data from a phase II study was used to develop a viral kine
Externí odkaz:
https://doaj.org/article/d1b7ce925d2e4b18b4554c4442799b30
Autor:
Johannes Kast, Saeideh Nozohouri, Di Zhou, Marc R. Yago, Po‐Wei Chen, Malidi Ahamadi, Sandeep Dutta, Vijay V. Upreti
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 9, Pp 2057-2074 (2022)
Abstract Advances in immuno‐oncology have provided a variety of novel therapeutics that harness the innate immune system to identify and destroy neoplastic cells. It is noteworthy that acceptable safety profiles accompany the development of these t
Externí odkaz:
https://doaj.org/article/8506c62661e546e89357bc447bb8e20a
Autor:
Ashit Trivedi, Winnie Sohn, Priyanka Kulkarni, Pegah Jafarinasabian, Hanze Zhang, Marintan Spring, Stephen Flach, Siddique Abbasi, Jan Wahlstrom, Edward Lee, Sandeep Dutta
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2510-2520 (2021)
Abstract Omecamtiv mecarbil (OM) is a novel cardiac myosin activator in development for the treatment of heart failure. In vitro, OM is an inhibitor of BCRP. Rosuvastatin, a BCRP substrate, is one of the most commonly prescribed medications in patien
Externí odkaz:
https://doaj.org/article/86aa2e97af2349d6999630760b8de569
Autor:
Marc R. Yago, Khamir Mehta, Maitreyee Bose, Sharvari Bhagwat, Vivek S. Chopra, Sandeep Dutta, Vijay V. Upreti
Publikováno v:
Clinical Pharmacokinetics. 62:779-788
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3b77a266089f56d4cd1f1e22c6ba5e
https://doi.org/10.1007/s40262-023-01242-6
https://doi.org/10.1007/s40262-023-01242-6
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 49:455-469
measures such as progression-free survival (PFS) and overall survival (OS) are commonly reported in literature for oncology trials, while time to progression (TTP) and post progression survival (PPS) are not usually reported. A time-variant transitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c144421efe865d1fda817a49d7c4a5b
https://doi.org/10.1007/s10928-022-09816-w
https://doi.org/10.1007/s10928-022-09816-w